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DDO recombinant protein :: D-Aspartate Oxidase (DDO) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2009963 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $200 +1 FREE 8GB USB
0.05 mg  /  $430 +1 FREE 8GB USB
0.1 mg  /  $665 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

D-Aspartate Oxidase (DDO), Recombinant Protein

 Also Known As   

Recombinant D-Aspartate Oxidase (DDO)

 Product Gene Name   

DDO recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF- E CPAYLPWLEK RIKGSGGWTL TRRIEDLWEL HPSFDIVVNC SGLGSRQLAG DSKIFPVRGQ VLQVQAPWVE HFIRDGSGLT YIYPGTSHVT LGGTRQKGDW NLSPDAENSR EILSRCCALE PSLHGACNIR EKVG
 Chromosome Location    Chromosome: 6; NC_000006.11 (110709545..110736839, complement). Location: 6q21
 OMIM    124450
 3D Structure    ModBase 3D Structure for Q99489
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Homo sapiens (Human)
 Expression System    Prokaryotic expression
 Residues    Glu170~Gly304 (Accession # Q99489) with N-terminal His-Tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of DDO recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for DDO recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for DDO recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of DDO recombinant protein    DDO recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for DDO. It may not necessarily be applicable to this product.
 NCBI GI #    40217815
 NCBI GeneID    8528
 NCBI Accession #    NP_003640.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003649.2 [Other Products]
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 UniProt Primary Accession #    Q99489 [Other Products]
 UniProt Secondary Accession #    Q5JXM4; Q5JXM5; Q5JXM6; Q8N552; A8KAG4 [Other Products]
 UniProt Related Accession #    Q99489 [Other Products]
 Molecular Weight    16.5kDa
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 NCBI Official Full Name    D-aspartate oxidase isoform a
 NCBI Official Synonym Full Names    D-aspartate oxidase
 NCBI Official Symbol    DDO [Similar Products]
 NCBI Official Synonym Symbols   
DASOX; DDO-1; DDO-2
[Similar Products]
 NCBI Protein Information    D-aspartate oxidase; aspartic oxidase; D-aspartate oxidase, DDO
 UniProt Protein Name    D-aspartate oxidase
 UniProt Gene Name    DDO [Similar Products]
 UniProt Synonym Gene Names    DASOX; DDO [Similar Products]
 UniProt Entry Name    OXDD_HUMAN
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 NCBI Summary for DDO    The protein encoded by this gene is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate. Flavin adenine dinucleotide or 6-hydroxyflavin adenine dinucleotide can serve as the cofactor in this reaction. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DDO    DDO: Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.4.3.1; Amino Acid Metabolism - alanine, aspartate and glutamate

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: peroxisome

Molecular Function: D-aspartate oxidase activity; protein binding; cofactor binding; receptor binding

Biological Process: grooming behavior; D-amino acid catabolic process; insemination; hormone metabolic process; aspartate metabolic process; aspartate catabolic process
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 Research Articles on DDO    1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with DDO recombinant proteinDiseases associated with DDO recombinant protein
 Products by Pathway  Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >9 publications with DDO and Neoplasms
 Disease Models, Animal Antibodies  >8 publications with DDO and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >7 publications with DDO and Neoplasms, Experimental
 Mental Disorders Antibodies  >3 publications with DDO and Mental Disorders
 Immune System Diseases Antibodies  >2 publications with DDO and Immune System Diseases
 Respiratory Tract Diseases Antibodies  >2 publications with DDO and Respiratory Tract Diseases
 Edema Antibodies  >2 publications with DDO and Edema
 Liver Neoplasms Antibodies  >1 publications with DDO and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with DDO and Liver Diseases
 Kidney Diseases Antibodies  >1 publications with DDO and Kidney Diseases
Organs/Tissues associated with DDO recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with DDO and Brain
 Kidney Antibodies  >12 publications with DDO and Kidney
 Liver Antibodies  >8 publications with DDO and Liver
 Eye Antibodies  >8 publications with DDO and Eye
 Muscle Antibodies  >6 publications with DDO and Muscle
 Placenta Antibodies  >1 publications with DDO and Placenta
 Uterus Antibodies  >1 publications with DDO and Uterus
 Skin Antibodies  >1 publications with DDO and Skin
 Lung Antibodies  >1 publications with DDO and Lung
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