NP_001271259.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57.3 kDa
NCBI Official Full Name
DNA-directed DNA/RNA polymerase mu isoform 2
NCBI Official Synonym Full Names
polymerase (DNA directed), mu
NCBI Protein Information
DNA-directed DNA/RNA polymerase mu; Pol iota; DNA polymerase mu; terminal transferase; polymerase (DNA-directed), mu
UniProt Protein Name
DNA-directed DNA/RNA polymerase mu
UniProt Synonym Protein Names
Terminal transferase
UniProt Synonym Gene Names
UniProt Entry Name
DPOLM_HUMAN
UniProt Comments for POLM
POLM: Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. Belongs to the DNA polymerase type-X family.
Protein type: EC 2.7.7.7; Transferase; DNA repair, damage
Chromosomal Location of Human Ortholog: 7p13
Cellular Component: nucleoplasm
Molecular Function: protein binding; DNA binding; metal ion binding; DNA-directed DNA polymerase activity
Biological Process: B cell differentiation; somatic hypermutation of immunoglobulin genes; DNA repair; DNA recombination
Research Articles on POLM
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Pathways associated with POLM recombinant protein
Diseases associated with POLM recombinant protein
Organs/Tissues associated with POLM recombinant protein
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