NP_116558.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,441 Da
NCBI Official Full Name
DNA-directed RNA polymerase II subunit RPB3
NCBI Official Synonym Full Names
RNA polymerase II subunit C
NCBI Protein Information
DNA-directed RNA polymerase II subunit RPB3
UniProt Protein Name
DNA-directed RNA polymerase II subunit RPB3
UniProt Synonym Protein Names
DNA-directed RNA polymerase II 33 kDa polypeptide; RPB33; DNA-directed RNA polymerase II subunit C; RPB31
UniProt Synonym Gene Names
RNA polymerase II subunit 3; RNA polymerase II subunit B3; RPB33 [Similar Products]
NCBI Summary for POLR2C
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008]
UniProt Comments for POLR2C
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft ().
Research Articles on POLR2C
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Products associated with POLR2C recombinant protein
Pathways associated with POLR2C recombinant protein
Diseases associated with POLR2C recombinant protein
Organs/Tissues associated with POLR2C recombinant protein
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