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dinB recombinant protein :: DNA polymerase IV (dinB) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1423494 dinB recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $760 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,010 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,015 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,120 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,260 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,280 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,335 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,595 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,845 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,905 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,030 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,450 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DNA polymerase IV (dinB), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Escherichia coli DNA polymerase IV (dinB)

 Product Gene Name   

dinB recombinant protein

[Similar Products]
 Product Synonym Gene Name    dinB [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1423494 COA    COA PDF
 Sequence Positions    1-351aa, full length protein
 Sequence    MRKIIHVDMD CFFAAVEMRD NPALRDIPIA IGGSRERRGV ISTANYPARK FGVRSAMPTG MALKLCPHLT LLPGRFDAYK EASNHIREIF SRYTSRIEPL SLDEAYLDVT DSVHCHGSAT LIAQEIRQTI FNELQLTASA GVAPVKFLAK IASDMNKPNG QFVITPAEVP AFLQTLPLAK IPGVGKVSAA KLEAMGLRTC GDVQKCDLVM LLKRFGKFGR ILWERSQGID ERDVNSERLR KSVGVERTMA EDIHHWSECE AIIERLYPEL ERRLAKVKPD LLIARQGVKL KFDDFQQTTQ EHVWPRLNKA DLIATARKTW DERRGGRGVR LVGLHVTLLD PQMERQLVLG L
 3D Structure    ModBase 3D Structure for Q47155
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Escherichia coli (strain K12)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of dinB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for dinB. It may not necessarily be applicable to this product.
 NCBI GI #    16128217
 NCBI GeneID    944922
 NCBI Accession #    NP_414766.1 [Other Products]
 NCBI GenBank Nucleotide #    NC_000913.3 [Other Products]
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 UniProt Primary Accession #    Q47155 [Other Products]
 UniProt Secondary Accession #    Q47683; Q8RJ78; Q8RJ81; Q8RJ86; Q8RJ87; Q8RNI5; Q8RNI6; Q8RNI7; Q8RNI8; Q8RNI9; Q8RNJ0 [Other Products]
 Molecular Weight    39,516 Da
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 NCBI Official Full Name    DNA polymerase IV
 NCBI Official Symbol    dinB [Similar Products]
 NCBI Official Synonym Symbols   
dinP; ECK0232; JW0221
[Similar Products]
 NCBI Protein Information    DNA polymerase IV
 UniProt Protein Name    DNA polymerase IV
 UniProt Synonym Protein Names   
Translesion synthesis polymerase IV
 Protein Family    DNA polymerase
 UniProt Gene Name    dinB [Similar Products]
 UniProt Synonym Gene Names    dinP; TSL polymerase IV [Similar Products]
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 NCBI Summary for dinB    Part of dinB-yafNOP operon. [More information is available at EcoGene: EG13141]. dinB encodes DNA polymerase IV (DNA pol IV), which belongs to the Y family of DNA polymerases . [More information is available at EcoCyc: G6115].
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 UniProt Comments for dinB    Poorly processive, error-prone DNA polymerase involved in translesion repair and untargeted mutagenesis (PubMed:10488344, PubMed:10801133). Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by Pol IV. Exhibits no 3'-5' exonuclease (proofreading) activity (PubMed:10488344). Overexpression of Pol IV results in increased frameshift mutagenesis. It is required for stationary-phase adaptive mutation, which provides the bacterium with flexibility in dealing with environmental stress, enhancing long-term survival and evolutionary fitness. Not seen to be involved in translesion snythesis even when stimulated by the beta slding-clamp and clamp-loading complex, which do however increase non-targeted DNA polymerse efficiency 3,000-fold, may be due to targeting to stalled replication forks on nondamaged DNA (PubMed:10801133, PubMed:16168375). Involved in translesional synthesis, in conjunction with the beta clamp from PolIII (PubMed:14592985, PubMed:14729336).
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 Research Articles on dinB    1. We hypothesize that damaged bases allow the switch to use of Pol IV during MBR by pausing the replicative polymerase to allow polymerase exchange in the replisome. The findings suggest that spontaneous mutation by MBR is regulated by regulation of the intracellular level of ROS
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with dinB recombinant protein
 Reference Product  PubMed Publications
 umuD recombinant protein  >27 publications with dinB and umuD
 mutS recombinant protein  >8 publications with dinB and mutS
 nusA recombinant protein  >5 publications with dinB and nusA
 polA recombinant protein  >4 publications with dinB and polA
 yafO recombinant protein  >3 publications with dinB and yafO
 yafN recombinant protein  >3 publications with dinB and yafN
 dnaN recombinant protein  >3 publications with dinB and dnaN
 recN recombinant protein  >2 publications with dinB and recN
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