NP_000938.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,144 Da
NCBI Official Full Name
DNA primase large subunit isoform a
NCBI Official Synonym Full Names
DNA primase subunit 2
NCBI Official Synonym Symbols
NCBI Protein Information
DNA primase large subunit
UniProt Protein Name
DNA primase large subunit
UniProt Synonym Protein Names
DNA primase 58 kDa subunit; p58
UniProt Synonym Gene Names
NCBI Summary for PRIM2
This gene encodes the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. Alternative splicing of this gene results in multiple transcript variants. This gene has a related pseudogene, which is also present on chromosome 6. [provided by RefSeq, Apr 2014]
UniProt Comments for PRIM2
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
Research Articles on PRIM2
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Products associated with PRIM2 recombinant protein
Pathways associated with PRIM2 recombinant protein
Diseases associated with PRIM2 recombinant protein
Organs/Tissues associated with PRIM2 recombinant protein
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