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DCN recombinant protein :: Decorin (DCN) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS956778 DCN recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $735 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $990 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $995 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,085 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,155 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,240 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,260 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,305 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,540 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,815 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,880 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,985 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,415 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Decorin (DCN), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Decorin (DCN)

 Product Gene Name   

DCN recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    31-359aa, Full Length of Mature Protein
 Sequence    DEASGIGPEV PDDRDFEPSL GPVCPFRCQC HLRVVQCSDL GLDKVPKDLP PDTTLLDLQN NKITEIKDGD FKNLKNLHAL ILVNNKISKV SPGAFTPLVK LERLYLSKNQ LKELPEKMPK TLQELRAHEN EITKVRKVTF NGLNQMIVIE LGTNPLKSSG IENGAFQGMK KLSYIRIADT NITSIPQGLP PSLTELHLDG NKISRVDAAS LKGLNNLAKL GLSFNSISAV DNGSLANTPH LRELHLDNNK LTRVPGGLAE HKYIQVVYLH NNNISVVGSS DFCPPGHNTK KASYSGVSLF SNPVQYWEIQ PSTFRCVYVR SAIQLGNYK
 OMIM    125255
 3D Structure    ModBase 3D Structure for P07585
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of DCN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for DCN recombinant protein

   This protein is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
NCBI/Uniprot data below describe general gene information for DCN. It may not necessarily be applicable to this product.
 NCBI GI #    4503271
 NCBI GeneID    1634
 NCBI Accession #    NP_001911.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001920.4 [Other Products]
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 UniProt Primary Accession #    P07585 [Other Products]
 UniProt Secondary Accession #    Q9P0Z0; Q9P0Z1; Q9Y5N8; Q9Y5N9 [Other Products]
 UniProt Related Accession #    P07585 [Other Products]
 Molecular Weight    8,266 Da
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 NCBI Official Full Name    decorin isoform a preproprotein
 NCBI Official Synonym Full Names    decorin
 NCBI Official Symbol    DCN [Similar Products]
 NCBI Official Synonym Symbols   
CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
[Similar Products]
 NCBI Protein Information    decorin
 UniProt Protein Name    Decorin
 UniProt Synonym Protein Names   
Bone proteoglycan II; PG-S2; PG40
 Protein Family    Decorin
 UniProt Gene Name    DCN [Similar Products]
 UniProt Synonym Gene Names    SLRR1B [Similar Products]
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 NCBI Summary for DCN    This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
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 UniProt Comments for DCN    May affect the rate of fibrils formation.
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 Research Articles on DCN    1. Genetic screening showed a deletion of chromosome 12q21.33-q22 containing the identified four small leucine-rich proteoglycans (SLRP's) associated with this particular dystrophy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DCN recombinant proteinPathways associated with DCN recombinant protein
 Reference Product  PubMed Publications
 TGFB1 recombinant protein  >93 publications with DCN and TGFB1
 VCAN recombinant protein  >72 publications with DCN and VCAN
 EGFR recombinant protein  >25 publications with DCN and EGFR
 MET recombinant protein  >17 publications with DCN and MET
 TGFB2 recombinant protein  >15 publications with DCN and TGFB2
 FBN1 recombinant protein  >8 publications with DCN and FBN1
 MMP2 recombinant protein  >8 publications with DCN and MMP2
 IGF1 recombinant protein  >5 publications with DCN and IGF1
 Products by Pathway  Pathway Diagram
 A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway antibodies  A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway Diagram
 CS/DS Degradation Pathway antibodies  CS/DS Degradation Pathway Diagram
 Chondroitin Sulfate Biosynthesis Pathway antibodies  Chondroitin Sulfate Biosynthesis Pathway Diagram
 Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies  Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
 Defective B3GALT6 Causes EDSP2 And SEMDJL1 Pathway antibodies  Defective B3GALT6 Causes EDSP2 And SEMDJL1 Pathway Diagram
 Defective B3GAT3 Causes JDSSDHD Pathway antibodies  Defective B3GAT3 Causes JDSSDHD Pathway Diagram
 Defective B4GALT7 Causes EDS, Progeroid Type Pathway antibodies  Defective B4GALT7 Causes EDS, Progeroid Type Pathway Diagram
 Defective CHST14 Causes EDS, Musculocontractural Type Pathway antibodies  Defective CHST14 Causes EDS, Musculocontractural Type Pathway Diagram
 Defective CHST3 Causes SEDCJD Pathway antibodies  Defective CHST3 Causes SEDCJD Pathway Diagram
 Defective CHSY1 Causes TPBS Pathway antibodies  Defective CHSY1 Causes TPBS Pathway Diagram
Diseases associated with DCN recombinant proteinOrgans/Tissues associated with DCN recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >173 publications with DCN and Cardiovascular Diseases
 Fibrosis Antibodies  >130 publications with DCN and Fibrosis
 Disease Models, Animal Antibodies  >106 publications with DCN and Disease Models, Animal
 Carcinoma Antibodies  >82 publications with DCN and Carcinoma
 Inflammation Antibodies  >60 publications with DCN and Inflammation
 Kidney Diseases Antibodies  >47 publications with DCN and Kidney Diseases
 Adenocarcinoma Antibodies  >29 publications with DCN and Adenocarcinoma
 Necrosis Antibodies  >25 publications with DCN and Necrosis
 Neoplasms, Experimental Antibodies  >25 publications with DCN and Neoplasms, Experimental
 Liver Diseases Antibodies  >24 publications with DCN and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >719 publications with DCN and Brain
 Nerve Antibodies  >307 publications with DCN and Nerve
 Connective Tissue Antibodies  >172 publications with DCN and Connective Tissue
 Skin Antibodies  >169 publications with DCN and Skin
 Bone Antibodies  >159 publications with DCN and Bone
 Muscle Antibodies  >159 publications with DCN and Muscle
 Vascular Antibodies  >141 publications with DCN and Vascular
 Ear Antibodies  >96 publications with DCN and Ear
 Kidney Antibodies  >84 publications with DCN and Kidney
 Embryonic Tissue Antibodies  >72 publications with DCN and Embryonic Tissue
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