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Dock11 recombinant protein :: Dedicator of cytokinesis protein 11 (Dock11) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1231835 Dock11 recombinant protein
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Dedicator of cytokinesis protein 11 (Dock11), Recombinant Protein

 Also Known As   

Recombinant Mouse Dedicator of cytokinesis protein 11 (Dock11) , partial

 Product Gene Name   

Dock11 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for A2AF47
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Dock11 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Dock11. It may not necessarily be applicable to this product.
 NCBI GI #    125660464
 NCBI GeneID    75974
 NCBI Accession #    NP_001009947.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001009947.3 [Other Products]
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 UniProt Primary Accession #    A2AF47 [Other Products]
 UniProt Secondary Accession #    Q5KTP7 [Other Products]
 UniProt Related Accession #    A2AF47 [Other Products]
 Molecular Weight    237,771 Da
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 NCBI Official Full Name    dedicator of cytokinesis protein 11
 NCBI Official Synonym Full Names    dedicator of cytokinesis 11
 NCBI Official Symbol    Dock11 [Similar Products]
 NCBI Official Synonym Symbols   
sph238; Zizimin2; 8030476J24; 5033414A21Rik
[Similar Products]
 NCBI Protein Information    dedicator of cytokinesis protein 11
 UniProt Protein Name    Dedicator of cytokinesis protein 11
 UniProt Synonym Protein Names   
Activated Cdc42-associated guanine nucleotide exchange factor; ACG; Zizimin-2
 Protein Family    Dedicator of cytokinesis protein
 UniProt Gene Name    Dock11 [Similar Products]
 UniProt Synonym Gene Names    ACG [Similar Products]
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 UniProt Comments for Dock11    Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP (PubMed:15710388, PubMed:16968698, PubMed:25851601). Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology (PubMed:25729399). Facilitates filopodia formation through the activation of CDC42 (PubMed:22494997).
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 Research Articles on Dock11    1. These data suggested that Zizimin2 is associated with the reduction of immune response in acquired immunity along with aging.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Dock11 recombinant proteinDiseases associated with Dock11 recombinant protein
 Products by Pathway  Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with Dock11 and Neoplasms
 Retinoblastoma Antibodies  >1 publications with Dock11 and Retinoblastoma
 Necrosis Antibodies  >1 publications with Dock11 and Necrosis
 Brain Diseases Antibodies  >1 publications with Dock11 and Brain Diseases
Organs/Tissues associated with Dock11 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >1 publications with Dock11 and Testis
 Skin Antibodies  >1 publications with Dock11 and Skin
 Bone Marrow Antibodies  >1 publications with Dock11 and Bone Marrow
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