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DHH recombinant protein :: Desert hedgehog protein (DHH) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1054194 DHH recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $785 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,030 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,050 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,160 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,205 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,275 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,305 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,365 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,645 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,875 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,930 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,075 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,495 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Desert hedgehog protein (DHH), Recombinant Protein

 Also Known As   

Recombinant Human Desert hedgehog protein (DHH)

 Product Gene Name   

DHH recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    23-396aa, Full Length of Mature Protein
 Sequence    CGPGRGPVGR RRYARKQLVP LLYKQFVPGV PERTLGASGP AEGRVARGSE RFRDLVPNYN PDIIFKDEEN SGADRLMTER CKERVNALAI AVMNMWPGVR LRVTEGWDED GHHAQDSLHY EGRALDITTS DRDRNKYGLL ARLAVEAGFD WVYYESRNHV HVSVKADNSL AVRAGGCFPG NATVRLWSGE RKGLRELHRG DWVLAADASG RVVPTPVLLF LDRDLQRRAS FVAVETEWPP RKLLLTPWHL VFAARGPAPA PGDFAPVFAR RLRAGDSVLA PGGDALRPAR VARVAREEAV GVFAPLTAHG TLLVNDVLAS CYAVLESHQW AHRAFAPLRL LHALGALLPG GAVQPTGMHW YSRLLYRLAE ELLG
 OMIM    233420
 3D Structure    ModBase 3D Structure for O43323
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of DHH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for DHH recombinant protein

   This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
NCBI/Uniprot data below describe general gene information for DHH. It may not necessarily be applicable to this product.
 NCBI GI #    19482158
 NCBI GeneID    50846
 NCBI Accession #    NP_066382.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021044.3 [Other Products]
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 UniProt Primary Accession #    O43323 [Other Products]
 UniProt Secondary Accession #    Q15794 [Other Products]
 UniProt Related Accession #    O43323 [Other Products]
 Molecular Weight    43,577 Da
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 NCBI Official Full Name    desert hedgehog protein preproprotein
 NCBI Official Synonym Full Names    desert hedgehog
 NCBI Official Symbol    DHH [Similar Products]
 NCBI Official Synonym Symbols   
GDXYM; HHG-3; SRXY7
[Similar Products]
 NCBI Protein Information    desert hedgehog protein
 UniProt Protein Name    Desert hedgehog protein
 UniProt Synonym Protein Names   
HHG-3
 Protein Family    Desert hedgehog protein
 UniProt Gene Name    DHH [Similar Products]
 UniProt Synonym Gene Names    DHH [Similar Products]
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 NCBI Summary for DHH    This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010]
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 UniProt Comments for DHH    Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
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 Research Articles on DHH    1. Single nucleotide polymorphism in the DHH gene is associated with bipolar disorder.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DHH recombinant proteinPathways associated with DHH recombinant protein
 Reference Product  PubMed Publications
 PTCH1 recombinant protein  >17 publications with DHH and PTCH1
 GLI3 recombinant protein  >11 publications with DHH and GLI3
 PTCH2 recombinant protein  >8 publications with DHH and PTCH2
 HHIP recombinant protein  >7 publications with DHH and HHIP
 SOX10 recombinant protein  >5 publications with DHH and SOX10
 BOC recombinant protein  >2 publications with DHH and BOC
 BMP4 recombinant protein  >2 publications with DHH and BMP4
 GAS1 recombinant protein  >1 publications with DHH and GAS1
 CDON recombinant protein  >1 publications with DHH and CDON
 Products by Pathway  Pathway Diagram
 Activation Of SMO Pathway antibodies  Activation Of SMO Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Hedgehog 'on' State Pathway antibodies  Hedgehog 'on' State Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Ligand Biogenesis Pathway antibodies  Hedgehog Ligand Biogenesis Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
Diseases associated with DHH recombinant proteinOrgans/Tissues associated with DHH recombinant protein
 Disease Name  Pubmed Publications
 Disorders of Sex Development Antibodies  >21 publications with DHH and Disorders of Sex Development
 Breast Neoplasms Antibodies  >9 publications with DHH and Breast Neoplasms
 Genital Diseases, Male Antibodies  >7 publications with DHH and Genital Diseases, Male
 Neoplasm Metastasis Antibodies  >6 publications with DHH and Neoplasm Metastasis
 Cell Transformation, Neoplastic Antibodies  >5 publications with DHH and Cell Transformation, Neoplastic
 Prostatic Diseases Antibodies  >5 publications with DHH and Prostatic Diseases
 46,XY Gonadal Dysgenesis, Complete or Partial, DHH-Related Antibodies  >5 publications with DHH and 46,XY Gonadal Dysgenesis, Complete or Partial, DHH-Related
 Lung Diseases Antibodies  >4 publications with DHH and Lung Diseases
 Nervous System Malformations Antibodies  >4 publications with DHH and Nervous System Malformations
 Infertility, Male Antibodies  >3 publications with DHH and Infertility, Male
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >47 publications with DHH and Testis
 Brain Antibodies  >20 publications with DHH and Brain
 Pancreas Antibodies  >7 publications with DHH and Pancreas
 Ganglia Antibodies  >3 publications with DHH and Ganglia
 Uterus Antibodies  >3 publications with DHH and Uterus
 Uncharacterized Tissue Antibodies  >2 publications with DHH and Uncharacterized Tissue
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