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Dsg3 recombinant protein :: Desmoglein-3 (Dsg3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1000327
SDS-PAGE
Unit / Price
0.05 mg (E-Coli)  /  $870 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $965 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,165 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,175 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,285 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,295 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,415 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,465 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,695 +2 FREE 8GB USB
1 mg (E-Coli)  /  $1,945 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,200 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,290 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,315 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $3,400 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Desmoglein-3 (Dsg3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Desmoglein-3 (Dsg3), partial

 Product Synonym Names    130 kDa pemphigus vulgaris antigen homolog
 Product Gene Name   

Dsg3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1000327 COA    COA PDF
 Sequence Positions    53-504. partial.
 Sequence    RLPADVSPIN YSLCLKPDLL DFTFEGKLEA AAQVRQATNQ IVMNCADIDI ITASYAPEGD EEIHATGFNY QNEDEKVTLS FPSTLQTGTG TLKIDFVGEL NDKMKGFYRS KYTTPSGEVR YAAVTQFEAT DARRAFPCWD EPAIKATFDI SLVVPKDRVA LSNMNVIDRK PYPDDENLVE VKFARTPVMS TYLVAFVVGE YDFVETRSKD GVCVRVYTPV GKAEQGKFAL EVAAKTLPFY KDYFNVPYPL PKIDLIAIAD FAAGAMENWG LVTYRETALL IDPKNSCSSS RQWVALVVGH ELAHQWFGNL VTMEWWTHLW LNEGFASWIE YLCVDHCFPE YDIWTQFVSA DYTRAQELDA LDNSHPIEVS VGHPSEVDEI FDAISYSKGA SVIRMLHDYI GDKDFKKGMN MYLTKFQQKN AATEDLWESL ENASGKPIAA VMNTWTKQMG FP
 3D Structure    ModBase 3D Structure for O35902
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Dsg3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Dsg3 recombinant protein

   Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
 Product Categories/Family for Dsg3 recombinant protein    Signal Transduction
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 SDS-PAGE of Dsg3 recombinant protein    Dsg3 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Dsg3. It may not necessarily be applicable to this product.
 NCBI GI #    25452923
 NCBI GeneID    13512
 NCBI Accession #    O35902.1 [Other Products]
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 UniProt Primary Accession #    O35902 [Other Products]
 UniProt Secondary Accession #    Q8CB02; Q8CE48 [Other Products]
 UniProt Related Accession #    O35902 [Other Products]
 Molecular Weight    79.18kD
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 NCBI Official Full Name    Desmoglein-3
 NCBI Official Synonym Full Names    desmoglein 3
 NCBI Official Symbol    Dsg3 [Similar Products]
 NCBI Official Synonym Symbols   
bal
[Similar Products]
 NCBI Protein Information    desmoglein-3
 UniProt Protein Name    Desmoglein-3
 UniProt Synonym Protein Names   
130 kDa pemphigus vulgaris antigen homolog
 Protein Family    Desmoglein
 UniProt Gene Name    Dsg3 [Similar Products]
 UniProt Entry Name    DSG3_MOUSE
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 NCBI Summary for Dsg3    This gene encodes a member of the cadherin family of proteins that forms an integral transmembrane component of desmosomes, the multiprotein complexes involved in cell adhesion, organization of the cytoskeleton, cell sorting and cell signaling. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Mice lacking the encoded protein exhibit loss of keratinocyte cell adhesion resulting in a phenotype that resembles that of patients with pemphigus vulgaris. This gene is located in a cluster of desmosomal cadherin genes on chromosome 18. [provided by RefSeq, Feb 2016]
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 UniProt Comments for Dsg3    DSG3: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Protein type: Membrane protein, integral; Cell adhesion

Cellular Component: cell junction; desmosome; integral to membrane; integral to plasma membrane; membrane; plasma membrane; spot adherens junction

Molecular Function: calcium ion binding; metal ion binding

Biological Process: cell adhesion; homophilic cell adhesion
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Product References and Citations for Dsg3 recombinant protein

   "cDNA cloning and chromosomal assignment of the mouse gene for desmoglein 3 (Dsg3), the pemphigus vulgaris antigen." Ishikawa H., Silos S.A., Tamai K., Copeland N.G., Gilbert D.J., Jenkins N.A., Uitto J. Mamm. Genome 5:803-804(1994)
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 Research Articles on Dsg3    1. Desmoglein 3 deficiency in mice leads to a phenotype characterized by cyclic alopecia in addition to the dramatic skin and mucocutaneous acantholysis observed in pemphigus patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Dsg3 recombinant proteinPathways associated with Dsg3 recombinant protein
 Reference Product  PubMed Publications
 Src recombinant protein  >9 publications with Dsg3 and Src
 Casp3 recombinant protein  >6 publications with Dsg3 and Casp3
 Jup recombinant protein  >5 publications with Dsg3 and Jup
 Pkp1 recombinant protein  >5 publications with Dsg3 and Pkp1
 Pkp3 recombinant protein  >2 publications with Dsg3 and Pkp3
 Col17a1 recombinant protein  >1 publications with Dsg3 and Col17a1
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cell Adhesion Proteins Pathway antibodies  Apoptotic Cleavage Of Cell Adhesion Proteins Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Programmed Cell Death Pathway antibodies  Programmed Cell Death Pathway Diagram
Organs/Tissues associated with Dsg3 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >8 publications with Dsg3 and Eye
 Tongue Antibodies  >4 publications with Dsg3 and Tongue
 Mammary Gland Antibodies  >1 publications with Dsg3 and Mammary Gland
 Vagina Antibodies  >1 publications with Dsg3 and Vagina
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