Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow SAT1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • ASPHD2 Antibody
 • IL-17A ELISA Kit
 • VAPA Recombinant Protein
 • Ataxia Telangiectasia Mutated (ATM) ELISA Kit
 • Cytokeratin (KRT8) Antibody
 • ras homolog gene family, member T1 (RHOT1) ELISA Kit
 • Insulin ELISA Kit
 • Carboxymethyl Lysine (CML) ELISA Kit
 • Secreted Phospholipase A2-IIE (PLA2G2E) Recombinant Protein
 • nei endonuclease VIII-like 1 (NEIL1) Antibody
 • E. coli (O & K antigens) Antibody
 • Stat3 Antibody
 • arachidonate 5-lipoxygenase (ALOX5) ELISA Kit
 • Cerebellin-3 (CBLN3) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

SAT1 recombinant protein :: Diamine N-acetyltransferase 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS203365
SDS-Page
Unit / Price
0.1 mg  /  $375 +1 FREE 8GB USB
0.5 mg  /  $925 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Diamine N-acetyltransferase 1 (SAT1), Recombinant Protein

★Popular Item★
 Also Known As   

Diamine N-acetyltransferase 1, 1-171aa, Human, His tag, E Coli

 Product Synonym Names    spermidine/spermine N1-acetyltransferase 1; DC21; KFSD; KFSDX; SAT; SSAT; SSAT-1; SAT1; Diamine acetyltransferase 1; EC 2.3.1.57; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; Spermidine/spermine N (1)-acetyltransferase 1; SSAT 1.
 Product Gene Name   

SAT1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    MGSSHHHHHH SSGLVPRGSH MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS EEGWRLFKID KEYLLKMATE E
 OMIM    M77693 mRNA
 3D Structure    ModBase 3D Structure for P21673
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing, 10% glycerol
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
Section Bar
 Antigen Species    Human
 Tag Information    His-tag
Section Bar
 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of SAT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for SAT1 recombinant protein

   Diamine N-acetyltransferase 1 (or Spermidine/spermine-N1-acetyltransferase, SSAT1), as known as SAT-1, is a polyamine catabolic enzyme which catalyzes the acetylation of polyamines. This protein plays an important role in polyamine homoeostasis, since acetylated products are either excreted from the cell or oxidized by acetylpolyamine oxidase. A variety of other effects of increased SAT-1 activity include death of pancreatic cells, blockage of regenerative tissue growth, behavioral changes, keratosis follicularis spinulosa decalvans (KFSD), and hair loss. Recombinant human SAT-1, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
 Product Categories/Family for SAT1 recombinant protein    Enzymes & Proteases
 Applications Tested/Suitable for SAT1 recombinant protein   

SDS-PAGE

Section Bar
 SDS-Page of SAT1 recombinant protein    SAT1 recombinant protein SDS-Page image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for SAT1. It may not necessarily be applicable to this product.
 NCBI GI #    4506789
 NCBI GeneID    6303
 NCBI Accession #    NP_002961 [Other Products]
 NCBI GenBank Nucleotide #    NM_002970.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P21673 [Other Products]
 UniProt Secondary Accession #    Q6ICU9 [Other Products]
 UniProt Related Accession #    P21673 [Other Products]
 Molecular Weight    22.1 kDa (191aa), confirmed by MALDI-TOF. [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    diamine acetyltransferase 1
 NCBI Official Synonym Full Names    spermidine/spermine N1-acetyltransferase 1
 NCBI Official Symbol    SAT1 [Similar Products]
 NCBI Official Synonym Symbols   
SAT; DC21; KFSD; SSAT; KFSDX; SSAT-1
[Similar Products]
 NCBI Protein Information    diamine acetyltransferase 1
 UniProt Protein Name    Diamine acetyltransferase 1
 UniProt Synonym Protein Names   
Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; Spermidine/spermine N(1)-acetyltransferase 1; SSAT; SSAT-1
 Protein Family    Diamine acetyltransferase
 UniProt Gene Name    SAT1 [Similar Products]
 UniProt Synonym Gene Names    SAT; SSAT; SSAT-1 [Similar Products]
Section Bar
 NCBI Summary for SAT1    The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]
Section Bar
 UniProt Comments for SAT1    Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N1-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N1- and N8-acetylspermidine), spermine, N1-acetylspermidine and N8-acetylspermidine.
Table BarTOPTable Bar
 

Product References and Citations for SAT1 recombinant protein

   Pegg AE., et al. (2008). Am J Physiol Endocrinol Metab. 294: E995-E1010,; Janne J., et al. (2006). J Cell Mol Med. 10 (4):933-45.;
Section Bar
 Research Articles on SAT1    1. Extracellular polyamines induced proliferation and cancer cell migration by inducing ODC and SSAT expression, and the Akt1-mediated pathway.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with SAT1 recombinant proteinPathways associated with SAT1 recombinant protein
 Reference Product  PubMed Publications
 ODC1 recombinant protein  >4 publications with SAT1 and ODC1
 SMOX recombinant protein  >2 publications with SAT1 and SMOX
 TNC recombinant protein  >1 publications with SAT1 and TNC
 MAOA recombinant protein  >1 publications with SAT1 and MAOA
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Ferroptosis Pathway antibodies  Ferroptosis Pathway Diagram
 Ferroptosis Pathway antibodies  Ferroptosis Pathway Diagram
 GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway antibodies  GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway Diagram
 GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway antibodies  GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway Diagram
 Interconversion Of Polyamines Pathway antibodies  Interconversion Of Polyamines Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
Diseases associated with SAT1 recombinant proteinOrgans/Tissues associated with SAT1 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >9 publications with SAT1 and Nervous System Diseases
 Brain Diseases Antibodies  >6 publications with SAT1 and Brain Diseases
 Liver Diseases Antibodies  >5 publications with SAT1 and Liver Diseases
 Kidney Diseases Antibodies  >5 publications with SAT1 and Kidney Diseases
 Inflammation Antibodies  >2 publications with SAT1 and Inflammation
 Cell Transformation, Neoplastic Antibodies  >2 publications with SAT1 and Cell Transformation, Neoplastic
 Cardiovascular Diseases Antibodies  >2 publications with SAT1 and Cardiovascular Diseases
 Hypertension Antibodies  >2 publications with SAT1 and Hypertension
 Poisoning Antibodies  >1 publications with SAT1 and Poisoning
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with SAT1 and Drug-Related Side Effects and Adverse Reactions
 Organ/Tissue Name  Pubmed Publications
 Mouth Antibodies  >46 publications with SAT1 and Mouth
 Blood Antibodies  >34 publications with SAT1 and Blood
 Brain Antibodies  >26 publications with SAT1 and Brain
 Kidney Antibodies  >16 publications with SAT1 and Kidney
 Intestine Antibodies  >8 publications with SAT1 and Intestine
 Liver Antibodies  >8 publications with SAT1 and Liver
 Vascular Antibodies  >5 publications with SAT1 and Vascular
 Muscle Antibodies  >4 publications with SAT1 and Muscle
 Bone Antibodies  >3 publications with SAT1 and Bone
 Prostate Antibodies  >2 publications with SAT1 and Prostate
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions