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DAO recombinant protein :: Diamine Oxidase (DAO) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2011939 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $245 +1 FREE 8GB USB
0.1 mg  /  $365 +1 FREE 8GB USB
0.2 mg  /  $450 +1 FREE 8GB USB
0.5 mg  /  $870 +1 FREE 8GB USB
1 mg  /  $1,280 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Diamine Oxidase (DAO), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Diamine Oxidase (DAO)

 Product Gene Name   

DAO recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with N-terminal His-Tag, its sequence is listed below.
 Chromosome Location    Chromosome: 7; NC_000007.13 (150524336..150558379). Location: 7q36.1
 OMIM    104610
 3D Structure    ModBase 3D Structure for P19801
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Homo sapiens (Human)
 Expression System    Prokaryotic expression
 Residues    Ala347~Asp466 (Accession # P19801) with N-terminal His-Tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of DAO recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for DAO recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for DAO recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of DAO recombinant protein    DAO recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for DAO. It may not necessarily be applicable to this product.
 NCBI GI #    73486661
 NCBI GeneID    26
 NCBI Accession #    NP_001082.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001091.3 [Other Products]
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 UniProt Primary Accession #    P19801 [Other Products]
 UniProt Secondary Accession #    Q16683; Q16684; Q56II4; Q6GU42 [Other Products]
 UniProt Related Accession #    P19801 [Other Products]
 Molecular Weight    15.0kDa
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 NCBI Official Full Name    amiloride-sensitive amine oxidase
 NCBI Official Synonym Full Names    amine oxidase, copper containing 1
 NCBI Official Symbol    AOC1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    amiloride-sensitive amine oxidase [copper-containing]; amiloride-sensitive amine oxidase [copper-containing]; histaminase; diamine oxidase; kidney amine oxidase; amiloride-binding protein 1; amine oxidase copper domain-containing protein 1; amiloride binding protein 1 (amine oxidase (copper-containing))
 UniProt Protein Name    Amiloride-sensitive amine oxidase [copper-containing]
 UniProt Synonym Protein Names   
Amiloride-binding protein 1; Amine oxidase copper domain-containing protein 1; Histaminase; Kidney amine oxidase
 Protein Family    D-amino-acid oxidase
 UniProt Gene Name    AOC1 [Similar Products]
 UniProt Synonym Gene Names    ABP1; DAO1; DAO; Diamine oxidase; KAO [Similar Products]
 UniProt Entry Name    AOC1_HUMAN
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 NCBI Summary for DAO    This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
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 UniProt Comments for DAO    ABP1: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Belongs to the copper/topaquinone oxidase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC; Oxidoreductase; Secreted, signal peptide; Amino Acid Metabolism - tryptophan; Secreted; Amino Acid Metabolism - histidine; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: extracellular space; tight junction; plasma membrane; peroxisome

Molecular Function: heparin binding; amine oxidase activity; protein homodimerization activity; copper ion binding; zinc ion binding; protein complex binding; cation channel activity; receptor activity; drug binding; calcium ion binding; sodium channel activity; quinone binding

Biological Process: response to drug; response to antibiotic; amine metabolic process
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 Research Articles on DAO    1. Serum diamine oxidase levels were influenced by the menstrual cycle.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with DAO recombinant proteinDiseases associated with DAO recombinant protein
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Histidine Metabolism Pathway antibodies  Histidine Metabolism Pathway Diagram
 Histidine Metabolism Pathway antibodies  Histidine Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Histamine Degradation Pathway antibodies  Histamine Degradation Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with DAO and Kidney Diseases
Organs/Tissues associated with DAO recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >3 publications with DAO and Kidney
 Connective Tissue Antibodies  >1 publications with DAO and Connective Tissue
 Liver Antibodies  >1 publications with DAO and Liver
 Blood Antibodies  >1 publications with DAO and Blood
 Intestine Antibodies  >1 publications with DAO and Intestine
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