Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow SAT1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • carcinoembryonic antigen-related cell adhesion molecule 5 (C... ELISA Kit
 • ACC alpha (ACACA) Blocking Peptide
 • Troponin I-Cardiac (69-86 Region) (TNNI3) Antibody
 • CD3 Antibody
 • Proteasome subunit alpha type-4 (PSMA4) Recombinant Protein
 • Heavy Chain Immunoglobulin (Ig Hc) ELISA Kit
 • LCK Antibody
 • ELF2 Antibody
 • S100 Calcium Binding Protein A6 (S100A6) Antibody
 • Lin28 Recombinant Protein
 • Transmembrane Protease, Serine 2 (TMPRSS2) ELISA Kit
 • Apolipoprotein A5 (Apo A5) ELISA Kit
 • SLC25A5 Antibody
 • albumin ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

SAT1 recombinant protein :: Diamine acetyltransferase 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS965461
SDS-PAGE
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $285 +1 FREE 8GB USB
0.2 mg  /  $460 +1 FREE 8GB USB
0.5 mg  /  $750 +1 FREE 8GB USB
1 mg  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Diamine acetyltransferase 1 (SAT1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Diamine acetyltransferase 1

 Product Synonym Names    Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; Spermidine/spermine N(1)-acetyltransferase 1; SSAT; SSAT-1
 Product Gene Name   

SAT1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    SAT [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    5-171aa; Full Length
 Sequence    VIRPATAADC SDILRLIKEL AKYEYMEEQV ILTEKDLLED GFGEHPFYHC LVAEVPKEHW TPEGHSIVGF AMYYFTYDPW IGKLLYLEDF FVMSDYRGFG IGSEILKNLS QVAMRCRCSS MHFLVAEWNE PSINFYKRRG ASDLSSEEGW RLFKIDKEYL LKMATEE
 OMIM    308800
 3D Structure    ModBase 3D Structure for P21673
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
Section Bar
 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SAT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for SAT1 recombinant protein

   Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine.
 Product Categories/Family for SAT1 recombinant protein    Metabolism
Section Bar
 SDS-PAGE of SAT1 recombinant protein    SAT1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for SAT1. It may not necessarily be applicable to this product.
 NCBI GI #    4506789
 NCBI GeneID    6303
 NCBI Accession #    NP_002961.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002970.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P21673 [Other Products]
 UniProt Related Accession #    P21673 [Other Products]
 Molecular Weight    46.9kD
Table BarTOPTable Bar
 NCBI Official Full Name    diamine acetyltransferase 1
 NCBI Official Synonym Full Names    spermidine/spermine N1-acetyltransferase 1
 NCBI Official Symbol    SAT1 [Similar Products]
 NCBI Official Synonym Symbols   
SAT; DC21; KFSD; SSAT; KFSDX; SSAT-1
[Similar Products]
 NCBI Protein Information    diamine acetyltransferase 1
 UniProt Protein Name    Diamine acetyltransferase 1
 UniProt Synonym Protein Names   
Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; Spermidine/spermine N(1)-acetyltransferase 1; SSAT; SSAT-1
 Protein Family    Diamine acetyltransferase
 UniProt Gene Name    SAT1 [Similar Products]
 UniProt Synonym Gene Names    SAT; SSAT; SSAT-1 [Similar Products]
 UniProt Entry Name    SAT1_HUMAN
Section Bar
 NCBI Summary for SAT1    The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]
Section Bar
 UniProt Comments for SAT1    SAT: Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine. Defects in SAT1 may be a cause of keratosis follicularis spinulosa decalvans X-linked (KFSDX). A rare disorder affecting the skin and the eye. Affected men show thickening of the skin of the neck, ears, and extremities, especially the palms and soles, loss of eyebrows, eyelashes and beard, thickening of the eyelids with blepharitis and ectropion, and corneal degeneration. Belongs to the acetyltransferase family.

Protein type: EC 2.3.1.57; Acetyltransferase; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: Xp22.1

Cellular Component: cytosol; intracellular

Molecular Function: diamine N-acetyltransferase activity; protein binding

Biological Process: angiogenesis; polyamine biosynthetic process; polyamine metabolic process; putrescine catabolic process; regulation of cell proliferation

Disease: Keratosis Follicularis Spinulosa Decalvans, X-linked
Table BarTOPTable Bar
 

Product References and Citations for SAT1 recombinant protein

   Isolation and characterization of a cDNA clone that codes for human spermidine/spermine N1-acetyltransferase.Casero R.A. Jr., Celano P., Ervin S.J., Applegren N.B., Wiest L., Pegg A.E.J. Biol. Chem. 266:810-814(1991)
Section Bar
 Research Articles on SAT1    1. Data suggest that SAT1 plays role in apoptosis; overexpression of SAT1 in human embryonic kidney cell line leads to a rapid depletion of spermidine and spermine, arrest in cell growth, and mitochondria-mediated apoptosis.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with SAT1 recombinant proteinPathways associated with SAT1 recombinant protein
 Reference Product  PubMed Publications
 ODC1 recombinant protein  >2 publications with SAT1 and ODC1
 MAOB recombinant protein  >1 publications with SAT1 and MAOB
 MAOA recombinant protein  >1 publications with SAT1 and MAOA
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway antibodies  GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway Diagram
 GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway antibodies  GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway Diagram
 Interconversion Of Polyamines Pathway antibodies  Interconversion Of Polyamines Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Metabolism Of Polyamines Pathway antibodies  Metabolism Of Polyamines Pathway Diagram
 Nucleotide Metabolism Pathway antibodies  Nucleotide Metabolism Pathway Diagram
Diseases associated with SAT1 recombinant proteinOrgans/Tissues associated with SAT1 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with SAT1 and Nervous System Diseases
 Kidney Diseases Antibodies  >5 publications with SAT1 and Kidney Diseases
 Brain Diseases Antibodies  >5 publications with SAT1 and Brain Diseases
 Disease Models, Animal Antibodies  >4 publications with SAT1 and Disease Models, Animal
 Liver Diseases Antibodies  >4 publications with SAT1 and Liver Diseases
 Hypertension Antibodies  >2 publications with SAT1 and Hypertension
 Inflammation Antibodies  >2 publications with SAT1 and Inflammation
 Fetal Growth Retardation Antibodies  >1 publications with SAT1 and Fetal Growth Retardation
 Cardiovascular Diseases Antibodies  >1 publications with SAT1 and Cardiovascular Diseases
 Fatty Liver Antibodies  >1 publications with SAT1 and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Mouth Antibodies  >35 publications with SAT1 and Mouth
 Blood Antibodies  >29 publications with SAT1 and Blood
 Brain Antibodies  >24 publications with SAT1 and Brain
 Kidney Antibodies  >15 publications with SAT1 and Kidney
 Intestine Antibodies  >7 publications with SAT1 and Intestine
 Liver Antibodies  >7 publications with SAT1 and Liver
 Vascular Antibodies  >5 publications with SAT1 and Vascular
 Muscle Antibodies  >4 publications with SAT1 and Muscle
 Uterus Antibodies  >2 publications with SAT1 and Uterus
 Nerve Antibodies  >2 publications with SAT1 and Nerve
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions