NP_417530.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
13,620 Da
NCBI Official Full Name
dihydroneopterin aldolase and dihydroneopterin triphosphate 2'-epimerase
NCBI Protein Information
dihydroneopterin aldolase and dihydroneopterin triphosphate 2'-epimerase
UniProt Protein Name
Dihydroneopterin aldolase
UniProt Synonym Protein Names
7,8-dihydroneopterin 2'-epimerase; 7,8-dihydroneopterin aldolase; 7,8-dihydroneopterin epimerase (EC:5.1.99.8
UniProt Synonym Gene Names
NCBI Summary for folB
The N-terminal sequence of native FolB(YgiG) is MDIVFIEQL (Jeff Green, personal comm. [More information is available at EcoGene: EG11673]. Dihydroneopterin aldolase is an enzyme in the tetrahydrofolate biosynthesis pathway, an important antibacterial drug target. [More information is available at EcoCyc: EG11673].
UniProt Comments for folB
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin at appreciable velocity.
Research Articles on folB
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Products associated with folB recombinant protein
Pathways associated with folB recombinant protein
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