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Dpp4 recombinant protein :: Dipeptidyl peptidase 4 (Dpp4) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS951894
SDS-PAGE
Unit / Price
0.05 mg (Yeast)  /  $120 +1 FREE 8GB USB
0.01 mg (E-Coli)  /  $135 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $255 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $420 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $665 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,090 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Dipeptidyl peptidase 4 (Dpp4), Recombinant Protein

 Also Known As   

Recombinant Rat Dipeptidyl peptidase 4 (Dpp4)

 Product Synonym Names    Dipeptidyl peptidase 4; EC=3.4.14.5; Bile canaliculus domain-specific membrane glycoprotein; Dipeptidyl peptidase IV; DPP IV; GP110 glycoprotein; T-cell activation antigen CD26; CD_antigen=; CD26Cleaved into the following 3 chains:; 1. Dipeptidyl peptidas
 Product Gene Name   

Dpp4 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Dpp4; Cd26 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    638-767aa; Partial
 Sequence    SMVLGSGSGV FKCGIAVAPV SRWEYYDSVY TERYMGLPTP EDNLDHYRNS TVMSRAENFK QVEYLLIHGT ADDNVHFQQS AQISKALVDA GVDFQAMWYT DEDHGIASST AHQHIYSHMS HFLQQCFSLR
 3D Structure    ModBase 3D Structure for P14740
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Dpp4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Dpp4 recombinant protein

   Dpp4; Cd26
 Product Categories/Family for Dpp4 recombinant protein    Immunology
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 SDS-PAGE of Dpp4 recombinant protein    Dpp4 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Dpp4. It may not necessarily be applicable to this product.
 NCBI GI #    6978773
 NCBI GeneID    25253
 NCBI Accession #    NP_036921.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012789.1 [Other Products]
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 UniProt Primary Accession #    P14740 [Other Products]
 UniProt Related Accession #    P14740 [Other Products]
 Molecular Weight    88,089 Da
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 NCBI Official Full Name    dipeptidyl peptidase 4
 NCBI Official Synonym Full Names    dipeptidylpeptidase 4
 NCBI Official Symbol    Dpp4 [Similar Products]
 NCBI Official Synonym Symbols   
CD26; DPPIV
[Similar Products]
 NCBI Protein Information    dipeptidyl peptidase 4; DPP IV; GP110 glycoprotein; dipeptidyl peptidase IV; T-cell activation antigen CD26; bile canaliculus domain-specific membrane glycoprotein
 UniProt Protein Name    Dipeptidyl peptidase 4
 UniProt Synonym Protein Names   
Bile canaliculus domain-specific membrane glycoprotein; Dipeptidyl peptidase IV; DPP IV; GP110 glycoprotein; T-cell activation antigen CD26; CD_antigen: CD26Cleaved into the following 3 chains:Dipeptidyl peptidase 4 membrane formAlternative name(s):Dipeptidyl peptidase IV membrane form
 Protein Family    Dipeptidyl peptidase
 UniProt Gene Name    Dpp4 [Similar Products]
 UniProt Synonym Gene Names    Cd26; DPP IV [Similar Products]
 UniProt Entry Name    DPP4_RAT
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 NCBI Summary for Dpp4    catalyzes the degradation of glucagon-like peptide-1 (Glp-1); involved in proteolysis and peptidolysis [RGD, Feb 2006]
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 UniProt Comments for Dpp4    DPP4: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF- kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. Belongs to the peptidase S9B family. DPPIV subfamily.

Protein type: Vesicle; Cell cycle regulation; Motility/polarity/chemotaxis; Cell adhesion; Cell surface; Protease; Membrane protein, integral; Endoplasmic reticulum; EC 3.4.14.5

Cellular Component: Golgi apparatus; intercellular canaliculus; cell surface; focal adhesion; endoplasmic reticulum; lysosomal membrane; integral to membrane; extracellular region; lipid raft; membrane; endocytic vesicle; lamellipodium; apical plasma membrane; plasma membrane; cell junction

Molecular Function: collagen binding; identical protein binding; protein homodimerization activity; protease binding; serine-type peptidase activity; dipeptidyl-peptidase activity; serine-type endopeptidase activity; peptide binding; receptor binding

Biological Process: regulation of cell-cell adhesion mediated by integrin; behavioral fear response; T cell activation; establishment of localization; positive regulation of cell proliferation; regulation of T cell mediated immunity; T cell costimulation; response to hypoxia; endothelial cell migration; proteolysis; cell adhesion
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 Research Articles on Dpp4    1. Maternal deprivation as a model for postnatal stress experience influences remarkably postnatal lung development of rats, which is significantly modulated by the DPP4-system.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Dpp4 recombinant proteinPathways associated with Dpp4 recombinant protein
 Reference Product  PubMed Publications
 Gip recombinant protein  >50 publications with Dpp4 and Gip
 Ada recombinant protein  >21 publications with Dpp4 and Ada
 Tnf recombinant protein  >9 publications with Dpp4 and Tnf
 Glp1r recombinant protein  >3 publications with Dpp4 and Glp1r
 Cxcr3 recombinant protein  >2 publications with Dpp4 and Cxcr3
 Prcp recombinant protein  >1 publications with Dpp4 and Prcp
 Xpnpep2 recombinant protein  >1 publications with Dpp4 and Xpnpep2
 Products by Pathway  Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
Diseases associated with Dpp4 recombinant proteinOrgans/Tissues associated with Dpp4 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >63 publications with Dpp4 and Cardiovascular Diseases
 Inflammation Antibodies  >49 publications with Dpp4 and Inflammation
 Disease Models, Animal Antibodies  >49 publications with Dpp4 and Disease Models, Animal
 Weight Loss Antibodies  >35 publications with Dpp4 and Weight Loss
 Heart Diseases Antibodies  >24 publications with Dpp4 and Heart Diseases
 Liver Diseases Antibodies  >24 publications with Dpp4 and Liver Diseases
 Kidney Diseases Antibodies  >19 publications with Dpp4 and Kidney Diseases
 Adenocarcinoma Antibodies  >17 publications with Dpp4 and Adenocarcinoma
 Necrosis Antibodies  >16 publications with Dpp4 and Necrosis
 Hypertension Antibodies  >16 publications with Dpp4 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >192 publications with Dpp4 and Blood
 Pancreas Antibodies  >57 publications with Dpp4 and Pancreas
 Liver Antibodies  >30 publications with Dpp4 and Liver
 Kidney Antibodies  >23 publications with Dpp4 and Kidney
 Heart Antibodies  >22 publications with Dpp4 and Heart
 Intestine Antibodies  >19 publications with Dpp4 and Intestine
 Vascular Antibodies  >16 publications with Dpp4 and Vascular
 Skin Antibodies  >14 publications with Dpp4 and Skin
 Bone Antibodies  >13 publications with Dpp4 and Bone
 Muscle Antibodies  >12 publications with Dpp4 and Muscle
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