NP_003803.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
92,130 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 23 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 23
NCBI Official Synonym Symbols
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 23; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 23
UniProt Synonym Protein Names
Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3; MDC-3
UniProt Synonym Gene Names
UniProt Entry Name
ADA23_HUMAN
NCBI Summary for ADAM23
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013]
UniProt Comments for ADAM23
ADAM23: May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q33
Cellular Component: integral to plasma membrane; extracellular region
Molecular Function: integrin binding; protein binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity
Biological Process: central nervous system development; cell adhesion; proteolysis
Research Articles on ADAM23
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Products associated with ADAM23 recombinant protein
Diseases associated with ADAM23 recombinant protein
Organs/Tissues associated with ADAM23 recombinant protein
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