Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow Adam8  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • D (2)-like dopamine receptor (d215) Recombinant Protein
 • RIP (RIPK1) Antibody
 • eNOS Antibody
 • 17-Hydroxyprogesterone (17-OHP) ELISA Kit
 • Neutrophil Gelatinase Associated Lipocalin-Lipocalin-2 (LCN2... Recombinant Protein
 • PGDS ELISA Kit
 • ABCC11 Antibody
 • Cy3 Conjugated Avidin Secondary Antibody
 • ARH (LDLRAP1) Antibody
 • Abz-Ala-Phe-Arg-Phe-Ser-Gln -EEDnp Enzyme Substrate
 • CD31 Antibody
 • Methotrexate (MTX) ELISA Kit
 • Cytochrome C Oxidase (COX) ELISA Kit
 • Trenbolone, 17 beta- Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

Adam8 recombinant protein :: Disintegrin and metalloproteinase domain-containing protein 8 (Adam8) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS959663 Adam8 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,440 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,440 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,670 +2 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,670 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,440 +3 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,440 +3 FREE 8GB USB
1 mg (Yeast)  /  $2,885 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,885 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Disintegrin and metalloproteinase domain-containing protein 8 (Adam8), Recombinant Protein

 Also Known As   

Recombinant Mouse Disintegrin and metalloproteinase domain-containing protein 8 (Adam8)

 Product Synonym Names    Disintegrin and metalloproteinase domain-containing protein 8; ADAM 8; EC=3.4.24.-; Cell surface antigen MS2; Macrophage cysteine-rich glycoprotein; CD_antigen=; CD156a
 Product Gene Name   

Adam8 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Adam8; Ms2 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    17-658
 Sequence    PGPP LPHVKQYEVV WPRRLAASRS RRALPSHWGQ YPESLSYALG TSGHVFTLHL RKNRDLLGSS YTETYSAANG SEVTEQLQEQ DHCLYQGHVE GYEGSAASIS TCAGLRGFFR VGSTVHLIEP LDADEEGQHA MYQAKHLQQK AGTCGVKDTN LNDLGPRALE IYRAQPRNWL IPRETRYVEL YVVADSQEFQ KLGSREAVRQ RVLEVVNHVD KLYQELSFRV VLVGLEIWNK DKFYISRYAN VTLENFLSWR EQNLQGQHPH DNVQLITGVD FIGSTVGLAK VSALCSRHSG AVNQDHSKNS IGVASTMAHE LGHNLGMSHD EDIPGCYCPE PREGGGCIMT ESIGSKFPRI FSRCSKIDLE SFVTKPQTGC LTNVPDVNRF VGGPVCGNLF VEHGEQCDCG TPQDCQNPCC NATTCQLVKG AECASGTCCH ECKVKPAGEV CRLSKDKCDL EEFCDGRKPT CPEDAFQQNG TPCPGGYCFD GSCPTLAQQC RDLWGPGARV AADSCYTFSI PPGCNGRMYS GRINRCGALY CEGGQKPLER SFCTFSSNHG VCHALGTGSN IDTFELVLQG TKCEEGKVCM DGSCQDLRVY RSENCSAKCN NHGVCNHKRE CHCHKGWAPP NCVQRLADVS DEQAASTS
 3D Structure    ModBase 3D Structure for Q05910
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Mus musculus (Mouse)
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Adam8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for Adam8. It may not necessarily be applicable to this product.
 NCBI GI #    6680642
 NCBI GeneID    11501
 NCBI Accession #    NP_031429.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007403.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q05910 [Other Products]
 UniProt Related Accession #    Q05910 [Other Products]
 Molecular Weight    90,046 Da
Table BarTOPTable Bar
 NCBI Official Full Name    disintegrin and metalloproteinase domain-containing protein 8 isoform 1
 NCBI Official Synonym Full Names    a disintegrin and metallopeptidase domain 8
 NCBI Official Symbol    Adam8 [Similar Products]
 NCBI Official Synonym Symbols   
MS2; CD156; CD156a; E430039A18Rik
[Similar Products]
 NCBI Protein Information    disintegrin and metalloproteinase domain-containing protein 8; ADAM 8; cell surface antigen MS2; macrophage cysteine-rich glycoprotein; a disintegrin and metalloprotease domain 8; a disintegrin and metalloprotease domain (ADAM) 8
 UniProt Protein Name    Disintegrin and metalloproteinase domain-containing protein 8
 UniProt Synonym Protein Names   
Cell surface antigen MS2; Macrophage cysteine-rich glycoprotein; CD_antigen: CD156a
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    Adam8 [Similar Products]
 UniProt Synonym Gene Names    Ms2; ADAM 8 [Similar Products]
 UniProt Entry Name    ADAM8_MOUSE
Section Bar
 NCBI Summary for Adam8    This gene encodes a member of the Adam family of proteins that contain the disintegrin and metalloprotease domains. The encoded protein is localized to the cell surface, where it is involved in the remodeling of extracellular matrix and cell migration. Mice lacking the encoded protein display persistent inflammation upon treatment with allergens. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]
Section Bar
 UniProt Comments for Adam8    ADAM8: Possible involvement in extravasation of leukocytes.

Protein type: Membrane protein, integral; Protease; EC 3.4.24.-; Motility/polarity/chemotaxis

Cellular Component: specific granule; cell surface; membrane; integral to plasma membrane; cytoplasm; integral to membrane; plasma membrane; podosome; dense core granule membrane

Molecular Function: integrin binding; peptidase activity; protein binding; metallopeptidase activity; zinc ion binding; hydrolase activity; metal ion binding; metalloendopeptidase activity; cell adhesion molecule binding; calcium ion binding

Biological Process: tissue morphogenesis; positive regulation of cell adhesion; blood vessel endothelial cell migration; cell-matrix adhesion; cell morphogenesis; proteolysis; positive regulation of membrane protein ectodomain proteolysis; leukocyte migration during inflammatory response; activation of NF-kappaB transcription factor; positive regulation of T cell differentiation in the thymus; positive regulation of cellular extravasation; positive regulation of protein kinase B signaling cascade; cell-cell adhesion; regulation of osteoclast differentiation; regulation of cell-cell adhesion; positive regulation of acute inflammatory response; positive regulation of bone resorption; angiogenesis; negative regulation of neuron apoptosis; inflammatory response; lymphocyte chemotaxis; positive regulation of inflammatory response
Table BarTOPTable Bar
 Research Articles on Adam8    1. ADAM8 has anti-inflammatory activities during allergic airway inflammation in mice
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with Adam8 recombinant proteinDiseases associated with Adam8 recombinant protein
 Products by Pathway  Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >37 publications with Adam8 and Inflammation
 Lung Diseases Antibodies  >20 publications with Adam8 and Lung Diseases
 Necrosis Antibodies  >18 publications with Adam8 and Necrosis
 Disease Models, Animal Antibodies  >13 publications with Adam8 and Disease Models, Animal
 Brain Diseases Antibodies  >8 publications with Adam8 and Brain Diseases
 Cardiovascular Diseases Antibodies  >8 publications with Adam8 and Cardiovascular Diseases
 Fibrosis Antibodies  >6 publications with Adam8 and Fibrosis
 Liver Diseases Antibodies  >6 publications with Adam8 and Liver Diseases
 Carcinoma, Squamous Cell Antibodies  >6 publications with Adam8 and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >6 publications with Adam8 and Lung Neoplasms
Organs/Tissues associated with Adam8 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >41 publications with Adam8 and Blood
 Lung Antibodies  >22 publications with Adam8 and Lung
 Bone Antibodies  >18 publications with Adam8 and Bone
 Brain Antibodies  >16 publications with Adam8 and Brain
 Liver Antibodies  >11 publications with Adam8 and Liver
 Connective Tissue Antibodies  >7 publications with Adam8 and Connective Tissue
 Bone Marrow Antibodies  >6 publications with Adam8 and Bone Marrow
 Heart Antibodies  >4 publications with Adam8 and Heart
 Adipose Tissue Antibodies  >4 publications with Adam8 and Adipose Tissue
 Joint Antibodies  >3 publications with Adam8 and Joint
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions