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DLG4 recombinant protein :: Disks large homolog 4 (DLG4) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS958975 DLG4 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,300 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,555 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,560 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,610 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,655 +2 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
0.5 mg (Yeast)  /  $1,820 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,335 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,360 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,450 +3 FREE 8GB USB
1 mg (Yeast)  /  $2,750 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $3,085 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Disks large homolog 4 (DLG4), Recombinant Protein

 Also Known As   

Recombinant Human Disks large homolog 4 (DLG4)

 Product Gene Name   

DLG4 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-724aa, Full length protein
 Sequence    MDCLCIVTTK KYRYQDEDTP PLEHSPAHLP NQANSPPVIV NTDTLEAPGY ELQVNGTEGE MEYEEITLER GNSGLGFSIA GGTDNPHIGD DPSIFITKII PGGAAAQDGR LRVNDSILFV NEVDVREVTH SAAVEALKEA GSIVRLYVMR RKPPAEKVME IKLIKGPKGL GFSIAGGVGN QHIPGDNSIY VTKIIEGGAA HKDGRLQIGD KILAVNSVGL EDVMHEDAVA ALKNTYDVVY LKVAKPSNAY LSDSYAPPDI TTSYSQHLDN EISHSSYLGT DYPTAMTPTS PRRYSPVAKD LLGEEDIPRE PRRIVIHRGS TGLGFNIVGG EDGEGIFISF ILAGGPADLS GELRKGDQIL SVNGVDLRNA SHEQAAIALK NAGQTVTIIA QYKPEEYSRF EAKIHDLREQ LMNSSLGSGT ASLRSNPKRG FYIRALFDYD KTKDCGFLSQ ALSFRFGDVL HVIDASDEEW WQARRVHSDS ETDDIGFIPS KRRVERREWS RLKAKDWGSS SGSQGREDSV LSYETVTQME VHYARPIIIL GPTKDRANDD LLSEFPDKFG SCVPHTTRPK REYEIDGRDY HFVSSREKME KDIQAHKFIE AGQYNSHLYG TSVQSVREVA EQGKHCILDV SANAVRRLQA AHLHPIAIFI RPRSLENVLE INKRITEEQA RKAFDRATKL EQEFTECFSA IVEGDSFEEI YHKVKRVIED LSGPYIWVPA RERL
 OMIM    602887
 3D Structure    ModBase 3D Structure for P78352
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of DLG4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for DLG4 recombinant protein

   This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for DLG4. It may not necessarily be applicable to this product.
 NCBI GI #    192447426
 NCBI GeneID    1742
 NCBI Accession #    NP_001122299.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001128827.2 [Other Products]
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 UniProt Primary Accession #    P78352 [Other Products]
 UniProt Secondary Accession #    Q92941; Q9UKK8; B7Z1S1; G5E939 [Other Products]
 UniProt Related Accession #    P78352 [Other Products]
 Molecular Weight    80,125 Da
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 NCBI Official Full Name    disks large homolog 4 isoform 2
 NCBI Official Synonym Full Names    discs large MAGUK scaffold protein 4
 NCBI Official Symbol    DLG4 [Similar Products]
 NCBI Official Synonym Symbols   
PSD95; SAP90; SAP-90
[Similar Products]
 NCBI Protein Information    disks large homolog 4
 UniProt Protein Name    Disks large homolog 4
 UniProt Synonym Protein Names   
Postsynaptic density protein 95; PSD-95; Synapse-associated protein 90; SAP-90; SAP90
 Protein Family    Disks large
 UniProt Gene Name    DLG4 [Similar Products]
 UniProt Synonym Gene Names    PSD95; PSD-95; SAP-90; SAP90 [Similar Products]
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 NCBI Summary for DLG4    This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DLG4    Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B ().
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 Research Articles on DLG4    1. a dual role for PSD-95 in stabilizing synaptic NMDARs by binding directly to GluN2B but also by promoting synaptic exclusion and degradation of the negative regulator STEP61.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DLG4 recombinant proteinPathways associated with DLG4 recombinant protein
 Reference Product  PubMed Publications
 ERBB4 recombinant protein  >3 publications with DLG4 and ERBB4
 CRIPT recombinant protein  >2 publications with DLG4 and CRIPT
 GRIN2A recombinant protein  >2 publications with DLG4 and GRIN2A
 GRIN1 recombinant protein  >1 publications with DLG4 and GRIN1
 GRIN2B recombinant protein  >1 publications with DLG4 and GRIN2B
 Products by Pathway  Pathway Diagram
 Activation Of Ca-permeable Kainate Receptor Pathway antibodies  Activation Of Ca-permeable Kainate Receptor Pathway Diagram
 Activation Of Kainate Receptors Upon Glutamate Binding Pathway antibodies  Activation Of Kainate Receptors Upon Glutamate Binding Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 CREB Phosphorylation Through The Activation Of CaMKII Pathway antibodies  CREB Phosphorylation Through The Activation Of CaMKII Pathway Diagram
 CREB Phosphorylation Through The Activation Of Ras Pathway antibodies  CREB Phosphorylation Through The Activation Of Ras Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 ErbB4 Signaling Events Pathway antibodies  ErbB4 Signaling Events Pathway Diagram
Diseases associated with DLG4 recombinant proteinOrgans/Tissues associated with DLG4 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >29 publications with DLG4 and Nervous System Diseases
 Brain Diseases Antibodies  >28 publications with DLG4 and Brain Diseases
 Death Antibodies  >9 publications with DLG4 and Death
 Drug Toxicity Antibodies  >7 publications with DLG4 and Drug Toxicity
 Substance-Related Disorders Antibodies  >7 publications with DLG4 and Substance-Related Disorders
 Movement Disorders Antibodies  >6 publications with DLG4 and Movement Disorders
 Cognition Disorders Antibodies  >5 publications with DLG4 and Cognition Disorders
 Pain Antibodies  >4 publications with DLG4 and Pain
 Learning Disorders Antibodies  >3 publications with DLG4 and Learning Disorders
 Child Development Disorders, Pervasive Antibodies  >3 publications with DLG4 and Child Development Disorders, Pervasive
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >78 publications with DLG4 and Brain
 Muscle Antibodies  >7 publications with DLG4 and Muscle
 Kidney Antibodies  >5 publications with DLG4 and Kidney
 Embryonic Tissue Antibodies  >3 publications with DLG4 and Embryonic Tissue
 Eye Antibodies  >3 publications with DLG4 and Eye
 Skin Antibodies  >2 publications with DLG4 and Skin
 Lung Antibodies  >1 publications with DLG4 and Lung
 Testis Antibodies  >1 publications with DLG4 and Testis
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