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Add To Compare List MAP2K2 recombinant protein :: Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2) Recombinant Protein Catalog # MBS1446826 Unit / Price 0.02 mg (E-Coli) / $950 +1 FREE 8GB USB 0.02 mg (Yeast) / $1,070 +1 FREE 8GB USB 0.1 mg (E-Coli) / $1,115 +1 FREE 8GB USB 0.1 mg (Yeast) / $1,215 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,275 +1 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,540 +1 FREE 8GB USB 0.1 mg (Baculovirus) / $1,830 +2 FREE 8GB USB 1 mg (E-Coli) / $2,030 +2 FREE 8GB USB 1 mg (Yeast) / $2,405 +3 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,420 +3 FREE 8GB USB 1 mg (Baculovirus) / $3,560 +4 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $6,105 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2), Recombinant Protein Full Product Name Recombinant Chicken Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2) Product Gene Name MAP2K2 recombinant protein[Similar Products] Product Synonym Gene Name MAP2K2[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 1-398, Full length protein Sequence MPAKRKPVLP ALTITPSPAE GPGPGGSAEA NLVDLQKKLE ELELDEQQKK RLEAFLTQKA KVGELKDDDF ERISELGAGN GGVVTKVQHK PSGLIMARKL IHLEIKPAIR NQIIRELQVL HECNSPYIVG FYGAFYSDGE ISICMEHMDG GSLDQVLKEA KRIPEEILGK VSIAVLRGLA YLREKHQIMH RDVKPSNILV NSRGEIKLCD FGVSGQLIDS MANSFVGTRS YMSPERLQGT HYSVQSDIWS MGLSLVELSI GRYPIPPPDS KELEAIFGRP VVDGAEGESH SVSPWARPPG RPISGHGMDS RPAMAIFELL DYIVNEPPPK LPNGVFTQDF QEFVNKCLIK NPAERADLKM LMNHTFIKRS EVEEVDFAGW LCKTLRLNQP STPTRAAV 3D Structure ModBase 3D Structure for Q90891 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Chicken Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of MAP2K2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for MAP2K2 recombinant protein This protein is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1ERK2 and MAPK2ERK3. The activation of this kinase itself is dependent on the SerThr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. NCBI/Uniprot data below describe general gene information for MAP2K2. It may not necessarily be applicable to this product. NCBI GI # 46048668 NCBI GeneID 396349 NCBI Accession # NP_990719.1 [Other Products] NCBI GenBank Nucleotide # NM_205388.1 [Other Products] UniProt Primary Accession # Q90891 [Other Products] UniProt Related Accession # Q90891[Other Products] Molecular Weight 44,078 Da TOP NCBI Official Full Name dual specificity mitogen-activated protein kinase kinase 2 NCBI Official Synonym Full Names mitogen-activated protein kinase kinase 2 NCBI Official Symbol MAP2K2 [Similar Products] NCBI Official Synonym Symbols MEK2 [Similar Products] NCBI Protein Information dual specificity mitogen-activated protein kinase kinase 2 UniProt Protein Name Dual specificity mitogen-activated protein kinase kinase 2 UniProt Synonym Protein Names ERK activator kinase 2; MAPK/ERK kinase 2; MEK2 Protein Family Dual specificity mitogen-activated protein kinase kinase UniProt Gene Name MAP2K2 [Similar Products] UniProt Synonym Gene Names MEK2; MKK2; PRKMK2; MAP kinase kinase 2; MAPKK 2; MEK2 [Similar Products] TOP TOP UniProt Comments for MAP2K2 Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (). Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. 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TOP Products associated with MAP2K2 recombinant protein Reference Product PubMed Publications MAPK1 recombinant protein >149 publications with MAP2K2 and MAPK1 BRAF recombinant protein >69 publications with MAP2K2 and BRAF RAF1 recombinant protein >17 publications with MAP2K2 and RAF1 MAP3K1 recombinant protein >8 publications with MAP2K2 and MAP3K1 PAK1 recombinant protein >5 publications with MAP2K2 and PAK1 MOS recombinant protein >4 publications with MAP2K2 and MOS MAP3K8 recombinant protein >1 publications with MAP2K2 and MAP3K8 Pathways associated with MAP2K2 recombinant protein Products by Pathway Pathway Diagram B Cell Receptor Signaling Pathway antibodies B Cell Receptor Signaling Pathway Diagram EGFR1 Signaling Pathway antibodies EGFR1 Signaling Pathway Diagram EPO Receptor Signaling Pathway antibodies EPO Receptor Signaling Pathway Diagram ERK Activation Pathway antibodies ERK Activation Pathway Diagram ERK2 Activation Pathway antibodies ERK2 Activation Pathway Diagram ErbB Signaling Pathway antibodies ErbB Signaling Pathway Diagram ErbB Signaling Pathway antibodies ErbB Signaling Pathway Diagram Gap Junction Pathway antibodies Gap Junction Pathway Diagram Gap Junction Pathway antibodies Gap Junction Pathway Diagram GnRH Signaling Pathway antibodies GnRH Signaling Pathway Diagram Diseases associated with MAP2K2 recombinant protein Disease Name Pubmed Publications Neoplasms Antibodies >141 publications with MAP2K2 and Neoplasms Skin Diseases Antibodies >41 publications with MAP2K2 and Skin Diseases Cardiovascular Diseases Antibodies >34 publications with MAP2K2 and Cardiovascular Diseases Heart Diseases Antibodies >27 publications with MAP2K2 and Heart Diseases Gastrointestinal Diseases Antibodies >24 publications with MAP2K2 and Gastrointestinal Diseases Necrosis Antibodies >23 publications with MAP2K2 and Necrosis Inflammation Antibodies >22 publications with MAP2K2 and Inflammation Nervous System Diseases Antibodies >20 publications with MAP2K2 and Nervous System Diseases Drug Toxicity Antibodies >18 publications with MAP2K2 and Drug Toxicity Breast Neoplasms Antibodies >17 publications with MAP2K2 and Breast Neoplasms Organs/Tissues associated with MAP2K2 recombinant protein Organ/Tissue Name Pubmed Publications Brain Antibodies >23 publications with MAP2K2 and Brain Liver Antibodies >14 publications with MAP2K2 and Liver Ovary Antibodies >7 publications with MAP2K2 and Ovary Embryonic Tissue Antibodies >7 publications with MAP2K2 and Embryonic Tissue Head Antibodies >5 publications with MAP2K2 and Head Small Intestine Antibodies >2 publications with MAP2K2 and Small Intestine TOP © 2006-24 MyBioSource.com. 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