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DYNLT1 recombinant protein :: Dynein light chain Tctex-type 1 (DYNLT1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS951809 DYNLT1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $505 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $675 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $745 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $830 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $910 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,025 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,045 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,045 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,065 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,515 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,555 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,630 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,030 +2 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Dynein light chain Tctex-type 1 (DYNLT1), Recombinant Protein

 Also Known As   

Recombinant Human Dynein light chain Tctex-type 1 (DYNLT1)

 Product Gene Name   

DYNLT1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-113aa, Full length protein
 OMIM    601554
 3D Structure    ModBase 3D Structure for P63172
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of DYNLT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for DYNLT1. It may not necessarily be applicable to this product.
 NCBI GI #    5730085
 NCBI GeneID    6993
 NCBI Accession #    NP_006510.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006519.3 [Other Products]
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 UniProt Primary Accession #    P63172 [Other Products]
 UniProt Secondary Accession #    Q15763; Q5VTU4 [Other Products]
 UniProt Related Accession #    P63172 [Other Products]
 Molecular Weight    12,452 Da
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 NCBI Official Full Name    dynein light chain Tctex-type 1 isoform 1
 NCBI Official Synonym Full Names    dynein light chain Tctex-type 1
 NCBI Official Symbol    DYNLT1 [Similar Products]
 NCBI Official Synonym Symbols   
CW-1; TCTEL1; tctex-1
[Similar Products]
 NCBI Protein Information    dynein light chain Tctex-type 1
 UniProt Protein Name    Dynein light chain Tctex-type 1
 UniProt Synonym Protein Names   
Protein CW-1; T-complex testis-specific protein 1 homolog
 Protein Family    Dynein
 UniProt Gene Name    DYNLT1 [Similar Products]
 UniProt Synonym Gene Names    TCTEL1; TCTEX-1; TCTEX1 [Similar Products]
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 NCBI Summary for DYNLT1    This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
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 UniProt Comments for DYNLT1    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. May also be a accessory component of axonemal dynein.Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation (). Unrelated to the role in retrograde microtubule-associated movement may play a role in the dimerization of cytoplasmic proteins/domains such as for ACVR2B. Binds to the cytoplasmic domain of ACVR2B and, in vitro, inhibits ACVR2B signaling (PubMed:27502274).
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 Research Articles on DYNLT1    1. DYNLT1 interacts with nucleoporins and plays a role in the dysregulation of gene expression and induction of hematopoietic cell proliferation by the leukemogenic nucleoporin fusion, NUP98-HOXA9
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DYNLT1 recombinant proteinPathways associated with DYNLT1 recombinant protein
 Reference Product  PubMed Publications
 DYNLL1 recombinant protein  >4 publications with DYNLT1 and DYNLL1
 PAFAH1B1 recombinant protein  >1 publications with DYNLT1 and PAFAH1B1
 Products by Pathway  Pathway Diagram
 Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway antibodies  Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway Diagram
 Neurotrophic Factor-mediated Trk Receptor Signaling Pathway antibodies  Neurotrophic Factor-mediated Trk Receptor Signaling Pathway Diagram
Diseases associated with DYNLT1 recombinant proteinOrgans/Tissues associated with DYNLT1 recombinant protein
 Disease Name  Pubmed Publications
 Genital Diseases, Male Antibodies  >2 publications with DYNLT1 and Genital Diseases, Male
 Necrosis Antibodies  >2 publications with DYNLT1 and Necrosis
 Cardiovascular Diseases Antibodies  >1 publications with DYNLT1 and Cardiovascular Diseases
 Hypertension Antibodies  >1 publications with DYNLT1 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with DYNLT1 and Brain
 Testis Antibodies  >3 publications with DYNLT1 and Testis
 Nerve Antibodies  >2 publications with DYNLT1 and Nerve
 Kidney Antibodies  >2 publications with DYNLT1 and Kidney
 Blood Antibodies  >2 publications with DYNLT1 and Blood
 Eye Antibodies  >2 publications with DYNLT1 and Eye
 Parathyroid Antibodies  >1 publications with DYNLT1 and Parathyroid
 Bone Antibodies  >1 publications with DYNLT1 and Bone
 Liver Antibodies  >1 publications with DYNLT1 and Liver
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