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EBAG9 recombinant protein

Scan QR to view Datasheet Catalog #    MBS203246
SDS-Page
Unit / Price
0.1 mg  /  $255 +1 FREE 8GB USB
0.5 mg  /  $535 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EBAG9, Recombinant Protein

 Also Known As   

EBAG9, 28-213aa, Human,His tag, E Coli

 Product Synonym Names    Estrogen receptor binding site associated antigen 9; EB9; PDAF; RCAS1; Estrogen receptor binding site associated antigen 9; EBAG9; Estrogen receptor binding site associated; antigen 9 BAG9; Cancer associated surface antigen; Cancer associated surface antigen RCAS1; EBAG 9; Estrogen receptor binding fragment associated gene 9 protein; PDAF; RCAS 1; RCAS1; Receptor binding cancer antigen expressed on SiSo cells.
 Product Gene Name   

EBAG9 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MRSGRGRKLS GDQITLPTTV DYSSVPKQTD VEEWTSWDED APTSVKIEGG NGNVATQQNS LEQLEPDYFK DMTPTIRKTQ KIVIKKREPL NFGIPDGSTG FSSRLAATQD LPFIHQSSEL GDLDTWQENT NAWEEEEDAA WQAEEVLRQQ KLADREKRAA EQQRKKMEKE AQRLMKKEQN KIGVKLS
 OMIM    AF006265 mRNA
 3D Structure    ModBase 3D Structure for O00559
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 Host    E Coli
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 Purity/Purification    > 90% by SDS PAGE
 Form/Format    Liquid in 20 mM Tris pH 8.0, 1 mM DTT, 2 mM EDTA, 10% glycerol
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of EBAG9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for EBAG9 recombinant protein

   Estrogen receptor binding site associated antigen 9, also known as EBAG9, is a type III transmembrane protein that is predominantly located in the Golgi. This protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers, such as advanced breast and prostate cancers. As the EBAG9 acts to inhibit the growth of receptor-binding cells and induced apoptosis of immune cells, cancer cells might evade immune surveillance. So immunodetection of EBAG9 expression can be a negative prognostic indicator. Recombinant human EBAG9 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
 Product Categories/Family for EBAG9 recombinant protein    Cancer
 Applications Tested/Suitable for EBAG9 recombinant protein   

SDS-PAGE

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 SDS-Page of EBAG9 recombinant protein    EBAG9 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for EBAG9. It may not necessarily be applicable to this product.
 NCBI GI #    4758230
 NCBI GeneID    9166
 NCBI Accession #    NP_004206 [Other Products]
 NCBI GenBank Nucleotide #    NM_004215.4 [Other Products]
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 UniProt Primary Accession #    O00559 [Other Products]
 UniProt Secondary Accession #    Q5Y8C7; Q6IB20; Q9BS76; A8K3N6 [Other Products]
 UniProt Related Accession #    O00559 [Other Products]
 Molecular Weight    23.4 kDa (207 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
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 NCBI Official Full Name    receptor-binding cancer antigen expressed on SiSo cells
 NCBI Official Synonym Full Names    estrogen receptor binding site associated, antigen, 9
 NCBI Official Symbol    EBAG9 [Similar Products]
 NCBI Official Synonym Symbols   
EB9; PDAF
[Similar Products]
 NCBI Protein Information    receptor-binding cancer antigen expressed on SiSo cells
 UniProt Protein Name    Receptor-binding cancer antigen expressed on SiSo cells
 UniProt Synonym Protein Names   
Cancer-associated surface antigen RCAS1; Estrogen receptor-binding fragment-associated gene 9 protein
 Protein Family    Receptor-binding cancer antigen
 UniProt Gene Name    EBAG9 [Similar Products]
 UniProt Synonym Gene Names    RCAS1 [Similar Products]
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 NCBI Summary for EBAG9    This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]
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 UniProt Comments for EBAG9    May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
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Product References and Citations for EBAG9 recombinant protein

   Kumagai J., et al., (2009) Int J Cancer.124 (4):816-26.; Yoshida S., et al., (2008) J Rheumatol. 35 (9):1716-22.;
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 Research Articles on EBAG9    1. Data suggest that joint detection of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) and carcinoembryonic antigen (CEA) can improve the diagnostic sensitivity and specificity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EBAG9 recombinant proteinDiseases associated with EBAG9 recombinant protein
 Reference Product  PubMed Publications
 SNAPIN recombinant protein  >2 publications with EBAG9 and SNAPIN
 ESR1 recombinant protein  >1 publications with EBAG9 and ESR1
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >19 publications with EBAG9 and Breast Neoplasms
 Lung Neoplasms Antibodies  >16 publications with EBAG9 and Lung Neoplasms
 Ovarian Neoplasms Antibodies  >13 publications with EBAG9 and Ovarian Neoplasms
 Liver Diseases Antibodies  >12 publications with EBAG9 and Liver Diseases
 Uterine Cervical Neoplasms Antibodies  >12 publications with EBAG9 and Uterine Cervical Neoplasms
 Ovarian Diseases Antibodies  >10 publications with EBAG9 and Ovarian Diseases
 Inflammation Antibodies  >5 publications with EBAG9 and Inflammation
 Nervous System Diseases Antibodies  >4 publications with EBAG9 and Nervous System Diseases
 Genital Diseases, Male Antibodies  >4 publications with EBAG9 and Genital Diseases, Male
 Brain Diseases Antibodies  >4 publications with EBAG9 and Brain Diseases
Organs/Tissues associated with EBAG9 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >70 publications with EBAG9 and Blood
 Lymph Node Antibodies  >32 publications with EBAG9 and Lymph Node
 Lymph Antibodies  >31 publications with EBAG9 and Lymph
 Uterus Antibodies  >21 publications with EBAG9 and Uterus
 Lung Antibodies  >18 publications with EBAG9 and Lung
 Placenta Antibodies  >17 publications with EBAG9 and Placenta
 Liver Antibodies  >16 publications with EBAG9 and Liver
 Stomach Antibodies  >10 publications with EBAG9 and Stomach
 Embryonic Tissue Antibodies  >10 publications with EBAG9 and Embryonic Tissue
 Connective Tissue Antibodies  >8 publications with EBAG9 and Connective Tissue
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