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HSP90B1 recombinant protein :: Endoplasmin (HSP90B1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1265357
SDS-Page
Unit / Price
0.01 mg  /  $150 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $285 +1 FREE 8GB USB
0.2 mg  /  $460 +1 FREE 8GB USB
0.5 mg  /  $750 +1 FREE 8GB USB
1 mg  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Endoplasmin (HSP90B1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Endoplasmin (HSP90B1), partial

 Product Synonym Names    94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog
 Product Gene Name   

HSP90B1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    GRP94; TRA1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    27-799. Partial
 Sequence    VDGTVEEDLG KSREGSRTDD EVVQREEEAI QLDGLNASQI RELREKSEKF AFQAEVNRMM KLIINSLYKN KEIFLRELIS NASDALDKIR LISLTDENAL SGNEELTVKI KCDKEKNLLH VTDTGVGMTR EELVKNLGTI AKSGTSEFLN KMTEAQEDGQ STSELIGQFG VGFYSAFLVA DKVIVTSKHN NDTQHIWESD SNEFSVIADP RGNTLGRGTT ITLVLKEEAS DYLELDTIKN LVKKYSQFIN FPIYVWSSKT ETVEEPMEEE EAAKEEKEES DDEAAVEEEE EEKKPKTKKV EKTVWDWELM NDIKPIWQRP SKEVEEDEYK AFYKSFSKES DDPMAYIHFT AEGEVTFKSI LFVPTSAPRG LFDEYGSKKS DYIKLYVRRV FITDDFHDMM PKYLNFVKGV VDSDDLPLNV SRETLQQHKL LKVIRKKLVR KTLDMIKKIA DDKYNDTFWK EFGTNIKLGV IEDHSNRTRL AKLLRFQSSH HPTDITSLDQ YVERMKEKQD KIYFMAGSSR KEAESSPFVE RLLKKGYEVI YLTEPVDEYC IQALPEFDGK RFQNVAKEGV KFDESEKTKE SREAVEKEFE PLLNWMKDKA LKDKIEKAVV SQRLTESPCA LVASQYGWSG NMERIMKAQA YQTGKDISTN YYASQKKTFE INPRHPLIRD MLRRIKEDED DKTVLDLAVV LFETATLRSG YLLPDTKAYG DRIERMLRLS LNIDPDAKVE EEPEEEPEET AEDTTEDTEQ DEDEEMDVGT DEEEETAKES TAE
 OMIM    191175
 3D Structure    ModBase 3D Structure for P14625
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of HSP90B1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for HSP90B1 recombinant protein

   Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. 1 Publication
 Product Categories/Family for HSP90B1 recombinant protein    Metabolism
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 SDS-Page of HSP90B1 recombinant protein    HSP90B1 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for HSP90B1. It may not necessarily be applicable to this product.
 NCBI GI #    4507677
 NCBI GeneID    7184
 NCBI Accession #    NP_003290.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003299.2 [Other Products]
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 UniProt Primary Accession #    P14625 [Other Products]
 UniProt Secondary Accession #    Q96A97 [Other Products]
 UniProt Related Accession #    P14625 [Other Products]
 Molecular Weight    93.2kD
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 NCBI Official Full Name    endoplasmin
 NCBI Official Synonym Full Names    heat shock protein 90kDa beta family member 1
 NCBI Official Symbol    HSP90B1 [Similar Products]
 NCBI Official Synonym Symbols   
ECGP; GP96; TRA1; GRP94; HEL35; HEL-S-125m
[Similar Products]
 NCBI Protein Information    endoplasmin
 UniProt Protein Name    Endoplasmin
 UniProt Synonym Protein Names   
94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog
 Protein Family    Endoplasmin
 UniProt Gene Name    HSP90B1 [Similar Products]
 UniProt Synonym Gene Names    GRP94; TRA1; GRP-94 [Similar Products]
 UniProt Entry Name    ENPL_HUMAN
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Product References and Citations for HSP90B1 recombinant protein

   Human homologue of murine tumor rejection antigen gp96 5'-regulatory and coding regions and relationship to stress-induced proteins.Maki R.G., Old L.J., Srivastava P.K.Proc. Natl. Acad. Sci. U.S.A. 87:5658-5662(1990) Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors.Chang S.C., Erwin A.E., Lee A.S.Mol. Cell. Biol. 9:2153-2162(1989) The association of heat shock protein gp96 with HBV-derived peptides in vitro.Meng S., Tien P. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.Nat. Biotechnol. 21:566-569(2003) A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.Meunier L., Usherwood Y.-K., Chung K.T., Hendershot L.M.Mol. Biol. Cell 13:4456-4469(2002) Proteomic analysis of early melanosomes identification of novel melanosomal proteins.Basrur V., Yang F., Kushimoto T., Higashimoto Y., Yasumoto K., Valencia J., Muller J., Vieira W.D., Watabe H., Shabanowitz J., Hearing V.J., Hunt D.F., Appella E.J. Proteome Res. 2:69-79(2003) Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.Zhang H., Li X.-J., Martin D.B., Aebersold R.Nat. Biotechnol. 21:660-666(2003) A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone.Liu B., Yang Y., Qiu Z., Staron M., Hong F., Li Y., Wu S., Li Y., Hao B., Bona R., Han D., Li Z.Nat. Commun. 1:79-79(2010) ErratumLiu B., Yang Y., Qiu Z., Staron M., Hong F., Li Y., Wu S., Li Y., Hao B., Bona R., Han D., Li Z.Nat. Commun. 3:653-653(2012) Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.Chi A., Valencia J.C., Hu Z.-Z., Watabe H., Yamaguchi H., Mangini N.J., Huang H., Canfield V.A., Cheng K.C., Yang F., Abe R., Yamagishi S., Shabanowitz J., Hearing V.J., Wu C., Appella E., Hunt D.F.J. Proteome Res. 5:3135-3144(2006) Elucidation of N-glycosylation sites on human platelet proteins a glycoproteomic approach.Lewandrowski U., Moebius J., Walter U., Sickmann A.Mol. Cell. Proteomics 5:226-233(2006) OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.Christianson J.C., Shaler T.A., Tyler R.E., Kopito R.R.Nat. Cell Biol. 10:272-282(2008) Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.J. Proteome Res. 8:651-661(2009) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.Sci. Signal. 3:RA3-RA3(2010) Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.Sci. Signal. 4:RS3-RS3(2011) A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.Cloutier P., Lavallee-Adam M., Faubert D., Blanchette M., Coulombe B.PLoS Genet. 9:E1003210-E1003210(2013) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HSP90B1 recombinant proteinPathways associated with HSP90B1 recombinant protein
 Reference Product  PubMed Publications
 HSPA5 recombinant protein  >8 publications with HSP90B1 and HSPA5
 PDIA6 recombinant protein  >2 publications with HSP90B1 and PDIA6
 P4HB recombinant protein  >2 publications with HSP90B1 and P4HB
 CALR recombinant protein  >2 publications with HSP90B1 and CALR
 Products by Pathway  Pathway Diagram
 ATF6-alpha Activates Chaperone Genes Pathway antibodies  ATF6-alpha Activates Chaperone Genes Pathway Diagram
 ATF6-alpha Activates Chaperones Pathway antibodies  ATF6-alpha Activates Chaperones Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
Diseases associated with HSP90B1 recombinant proteinOrgans/Tissues associated with HSP90B1 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5 publications with HSP90B1 and Inflammation
 Liver Diseases Antibodies  >4 publications with HSP90B1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >3 publications with HSP90B1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >3 publications with HSP90B1 and Liver Neoplasms
 Lung Diseases Antibodies  >3 publications with HSP90B1 and Lung Diseases
 Disease Models, Animal Antibodies  >3 publications with HSP90B1 and Disease Models, Animal
 Testicular Diseases Antibodies  >2 publications with HSP90B1 and Testicular Diseases
 Neoplasms, Experimental Antibodies  >2 publications with HSP90B1 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >2 publications with HSP90B1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >2 publications with HSP90B1 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with HSP90B1 and Blood
 Brain Antibodies  >6 publications with HSP90B1 and Brain
 Bone Antibodies  >5 publications with HSP90B1 and Bone
 Liver Antibodies  >4 publications with HSP90B1 and Liver
 Bone Marrow Antibodies  >4 publications with HSP90B1 and Bone Marrow
 Lung Antibodies  >3 publications with HSP90B1 and Lung
 Testis Antibodies  >3 publications with HSP90B1 and Testis
 Prostate Antibodies  >2 publications with HSP90B1 and Prostate
 Lymph Node Antibodies  >2 publications with HSP90B1 and Lymph Node
 Thyroid Antibodies  >2 publications with HSP90B1 and Thyroid
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