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EGF recombinant protein :: Epidermal Growth Factor Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS650926 EGF recombinant protein
Unit / Price
0.1 mg  /  $280 +1 FREE 8GB USB
0.5 mg  /  $355 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Epidermal Growth Factor (EGF), Recombinant Protein

 Also Known As   

Epidermal Growth Factor, Recombinant, Human (E. coli) (EGF)

 Product Gene Name   

EGF recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR
 Chromosome Location    Chromosome: 4; NC_000004.11 (110834040..110934118). Location: 4q25
 3D Structure    ModBase 3D Structure for Q6QBS2
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 Host    E Coli
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 Purity/Purification    Highly Purified
98% ([SDS-PAGE and HPLC)
 Form/Format    Supplied as a lyophillized powder. Reconstitute with sterile ddH2O, 0.1% HSA or BSA to 100ug/ml, which can then be further diluted to other aqueous solutions.
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 Biological Activity    ED50 calculated by the dose-dependent proliferation of murine BALB/c 3T3 cells (measured by 3H-thymidine uptake) is <0.1ng/ml corresponding to a specific activity of 1x10e7units/mg.
 Protein Content    EGF quantitation was carried out by two independent methods:
1. UV spectroscopy at 280nm using the absorbency value of 2.858 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).
2. Analysis by RP-HPLC, using a calibrated solution of EGF as a Reference Standard.
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Reconstitute with sterile ddH2O, 0.1% HSA or BSA. Aliquot and store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of EGF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for EGF recombinant protein

   Epidermal Growth Factor (EGF) is a polypeptide growth factor which stimulates the proliferation of a wide range of epidermal and epithelial cells. Human EGF is a 6.2kD protein containing 53 amino acid residues.
 Product Categories/Family for EGF recombinant protein    Growth Factors, Cytokines; Growth Factors-EGF
NCBI/Uniprot data below describe general gene information for EGF. It may not necessarily be applicable to this product.
 NCBI GI #    46242544
 NCBI GeneID    1950
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 UniProt Primary Accession #    Q6QBS2 [Other Products]
 UniProt Related Accession #    P01133; Q6QBS2 [Other Products]
 Molecular Weight    6.2kD [Similar Products]
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 NCBI Official Full Name    epidermal growth factor
 NCBI Official Synonym Full Names    epidermal growth factor
 NCBI Official Symbol    EGF [Similar Products]
 NCBI Official Synonym Symbols   
URG; HOMG4
[Similar Products]
 NCBI Protein Information    pro-epidermal growth factor; beta-urogastrone; OTTHUMP00000162922; OTTHUMP00000219721; OTTHUMP00000219722
 UniProt Protein Name    Epidermal growth factor
 Protein Family    Epidermal growth factor
 UniProt Gene Name    EGF [Similar Products]
 UniProt Entry Name    Q6QBS2_HUMAN
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 NCBI Summary for EGF    This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
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 Research Articles on EGF    1. Data show that males, but not females, who are A carriers for EGF +61 have an increased risk for developing gastric cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EGF recombinant proteinPathways associated with EGF recombinant protein
 Reference Product  PubMed Publications
 EGFR recombinant protein  >4126 publications with EGF and EGFR
 ERBB2 recombinant protein  >1134 publications with EGF and ERBB2
 GRB2 recombinant protein  >325 publications with EGF and GRB2
 ERBB3 recombinant protein  >217 publications with EGF and ERBB3
 Products by Pathway  Pathway Diagram
 Arf6 Signaling Events Pathway antibodies  Arf6 Signaling Events Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Ceramide Signaling Pathway antibodies  Ceramide Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Delta-Notch Signaling Pathway antibodies  Delta-Notch Signaling Pathway Diagram
 EGF Receptor (ErbB1) Signaling Pathway antibodies  EGF Receptor (ErbB1) Signaling Pathway Diagram
 EGFR Downregulation Pathway antibodies  EGFR Downregulation Pathway Diagram
 EGFR Interacts With Phospholipase C-gamma Pathway antibodies  EGFR Interacts With Phospholipase C-gamma Pathway Diagram
Diseases associated with EGF recombinant proteinOrgans/Tissues associated with EGF recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6899 publications with EGF and Neoplasms
 Breast Neoplasms Antibodies  >1366 publications with EGF and Breast Neoplasms
 Adenocarcinoma Antibodies  >1086 publications with EGF and Adenocarcinoma
 Carcinoma, Squamous Cell Antibodies  >1034 publications with EGF and Carcinoma, Squamous Cell
 Cell Transformation, Neoplastic Antibodies  >777 publications with EGF and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >716 publications with EGF and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >580 publications with EGF and Lung Neoplasms
 Drug Toxicity Antibodies  >560 publications with EGF and Drug Toxicity
 Head and Neck Neoplasms Antibodies  >546 publications with EGF and Head and Neck Neoplasms
 Neoplasm Metastasis Antibodies  >455 publications with EGF and Neoplasm Metastasis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1523 publications with EGF and Brain
 Kidney Antibodies  >1438 publications with EGF and Kidney
 Lung Antibodies  >1356 publications with EGF and Lung
 Skin Antibodies  >1184 publications with EGF and Skin
 Muscle Antibodies  >1159 publications with EGF and Muscle
 Embryonic Tissue Antibodies  >997 publications with EGF and Embryonic Tissue
 Mouth Antibodies  >808 publications with EGF and Mouth
 Intestine Antibodies  >805 publications with EGF and Intestine
 Eye Antibodies  >790 publications with EGF and Eye
 Placenta Antibodies  >430 publications with EGF and Placenta
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