View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Epididymis protein 4, HE4 Recombinant Protein Catalog # MBS355616 Unit / Price 0.1 mg / $675 +1 FREE 8GB USB 5x0.1 mg / $2,690 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Epididymis protein 4, HE4, Recombinant Protein Popular Item Full Product Name Human Epididymis protein 4, HE4 Protein (Active) Product Synonym Names Human Epididymis protein 4; HE4; WAP four-disulfide core domain protein 2; WFDC2 Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP MBS355616 COA COA PDF MBS355616 Technical Datasheet Technical Datasheet PDF Host E. coli Purity/Purification >95% by SDS-PAGE Form/Format Liquid; Each vial contains Tris-HCL (pH7.4 ± 0.2) with 0.2% sodium azide. Concentration 1 mg/ml (lot specific) Preparation and Storage Upon receipt, aliquot and store at -20°C or -80°C for long term.Avoid repeated freeze thaw cycles. Other Notes Small volumes of Epididymis protein 4, HE4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Epididymis protein 4, HE4 recombinant protein Description: Recombinant full length human HE4 protein with molecular weight 14 kDa.Background: WAP four-disulfide core domain protein 2, also known as Human Epididymis Protein 4 (HE4) is a protein that in humans is encoded by the WFDC2 gene. This gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low. Although the function of the HE4 protein is unknown, it is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. HE4 is a secreted glycoprotein that is overexpressed by serous and endometrioid EOCs (epithelial ovarian carcinomas). Its expression in cortical inclusion cysts suggests that formation of Mullerian epithelium is a prerequisite step in the development of some types of EOCs. Applications Tested/Suitable for Epididymis protein 4, HE4 recombinant protein ELISA, SDS-PAGE Application Notes for Epididymis protein 4, HE4 recombinant protein Other applications have not been tested. The optimal dilutions should be determined by end user. TOP Product References and Citations for Epididymis protein 4, HE4 recombinant protein 1. Hellström, Ingegerd; John Raycraft, Martha Hayden-Ledbetter, Jeffrey A. Ledbetter, Michèl Schummer, Martin McIntosh, Charles Drescher, Nicole Urban, and Karl Erik Hellström (2003-07-01). "The HE4 (WFDC2) Protein Is a Biomarker for Ovarian Carcinoma". Cancer Research 63 (13): 3695-3700. 2. Drapkin R, von Horsten HH, Lin Y et al. (2005). "Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas". Cancer Res. 65 (6): 2162-9. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP