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eIL 1 beta recombinant protein :: Equine Interleukin-1 beta Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142287 eIL 1 beta recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $4,585 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Equine Interleukin-1 beta (eIL 1 beta), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Equine Interleukin-1 beta

 Product Synonym Names    IL 1 beta Equine; Interleukin-1 beta Equine Recombinant; Catabolin; Lymphocyte-activating factor (LAF); Endogenous Pyrogen (EP); Leukocyte Endogenous Mediator (LEM); Mononuclear Cell Factor (MCF); IL1F2; IL-1 beta
 Product Gene Name   

eIL 1 beta recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    AAMHSVNCRL RDIYHKSLVL SGACELQAVH LNGENTNQQV VFCMSFVQGE EETDKIPVAL GLKEKNLYLS CGMKDGKPTL QLETVDPNTY PKRKMEKRFV FNKMEIKGNV EFESAMYPNW YISTSQAEKS PVFLGNTRGG RDITDFIMEI TSA
 3D Structure    ModBase 3D Structure for Q28386
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 Host    E Coli
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 Purity/Purification    Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    The IL 1 beta was lyophilized from a 0.2 um filtered concentrated solution in PBS pH 7.4, containing 0.1 % Tween-80.
Sterile Filtered White lyophilized (freeze-dried) powder.
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 Solubility    It is recommended to reconstitute the lyophilized IL 1 beta in sterile distilled H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
 Biological Activity    Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 20 pg/ml, corresponding to a specific activity of > 5.0 x 107 IU/mg.
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 Other Notes    Small volumes of eIL 1 beta recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for eIL 1 beta recombinant protein

   Description: Recombinant IL 1 beta Equine produced in E Coli cells is a non-glycosylated, homodimeric protein containing 153 amino acid chain and having a molecular mass of 17.3kDa. The IL 1 beta is purified by proprietary chromatographic techniques.

Introduction: Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
 Product Categories/Family for eIL 1 beta recombinant protein    CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
NCBI/Uniprot data below describe general gene information for eIL 1 beta. It may not necessarily be applicable to this product.
 NCBI GI #    126722831
 NCBI GeneID    100034237
 NCBI Accession #    NP_001075995.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001082526.1 [Other Products]
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 UniProt Primary Accession #    Q28386 [Other Products]
 UniProt Secondary Accession #    O18995; O77744 [Other Products]
 UniProt Related Accession #    Q28386 [Other Products]
 Molecular Weight    24,212 Da
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 NCBI Official Full Name    interleukin-1 beta
 NCBI Official Symbol    IL1B [Similar Products]
 NCBI Official Synonym Symbols   
IL-1B
[Similar Products]
 NCBI Protein Information    interleukin-1 beta; IL-1 beta
 UniProt Protein Name    Interleukin-1 beta
 UniProt Gene Name    IL1B [Similar Products]
 UniProt Synonym Gene Names    IL-1 beta [Similar Products]
 UniProt Entry Name    IL1B_HORSE
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 UniProt Comments for eIL 1 beta    Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
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 Research Articles on eIL 1 beta    1. Increased PGE2 production led to reduction in 5-LO products in LPS-treated equine whole blood via IL-1b.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with eIL 1 beta recombinant proteinDiseases associated with eIL 1 beta recombinant protein
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >427 publications with eIL 1 beta and Inflammation
 Necrosis Antibodies  >269 publications with eIL 1 beta and Necrosis
 Skin Diseases Antibodies  >56 publications with eIL 1 beta and Skin Diseases
 Stomach Neoplasms Antibodies  >43 publications with eIL 1 beta and Stomach Neoplasms
 Hypersensitivity Antibodies  >27 publications with eIL 1 beta and Hypersensitivity
 Arthritis, Rheumatoid Antibodies  >27 publications with eIL 1 beta and Arthritis, Rheumatoid
 Adenocarcinoma Antibodies  >24 publications with eIL 1 beta and Adenocarcinoma
 Asthma Antibodies  >22 publications with eIL 1 beta and Asthma
 Myocardial Ischemia Antibodies  >21 publications with eIL 1 beta and Myocardial Ischemia
 Colitis Antibodies  >20 publications with eIL 1 beta and Colitis
Organs/Tissues associated with eIL 1 beta recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >351 publications with eIL 1 beta and Blood
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