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Slc1a2 recombinant protein :: Excitatory amino acid transporter 2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS968106
SDS-PAGE
Unit / Price
0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Excitatory amino acid transporter 2 (Slc1a2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Excitatory amino acid transporter 2

 Product Synonym Names    GLT-1; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2
 Product Gene Name   

Slc1a2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    143-238aa; Extracellular Domain
 Sequence    HPGNPKLKKQ LGPGKKNDEV SSLDAFLDLI RNLFPENLVQ ACFQQIQTVT KKVLVAPPSE EANTTKAVIS MLNETMNEAP EETKIVIKKG LEFKDG
 3D Structure    ModBase 3D Structure for P43006
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Slc1a2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Slc1a2 recombinant protein

   Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly roving released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
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 SDS-PAGE of Slc1a2 recombinant protein    Slc1a2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Slc1a2. It may not necessarily be applicable to this product.
 NCBI GI #    117606277
 NCBI GeneID    20511
 NCBI Accession #    NP_001070982.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001077514.3 [Other Products]
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 UniProt Primary Accession #    P43006 [Other Products]
 UniProt Secondary Accession #    O35877; O54686; O54687 [Other Products]
 UniProt Related Accession #    P43006 [Other Products]
 Molecular Weight    38kD
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 NCBI Official Full Name    excitatory amino acid transporter 2 isoform 1
 NCBI Official Synonym Full Names    solute carrier family 1 (glial high affinity glutamate transporter), member 2
 NCBI Official Symbol    Slc1a2 [Similar Products]
 NCBI Official Synonym Symbols   
GLT1; Eaat2; GLT-1; MGLT1; AI159670; 1700091C19Rik; 2900019G14Rik
[Similar Products]
 NCBI Protein Information    excitatory amino acid transporter 2
 UniProt Protein Name    Excitatory amino acid transporter 2
 UniProt Synonym Protein Names   
GLT-1; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2
 Protein Family    Excitatory amino acid transporter
 UniProt Gene Name    Slc1a2 [Similar Products]
 UniProt Synonym Gene Names    Eaat2; Glt1 [Similar Products]
 UniProt Entry Name    EAA2_MOUSE
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 UniProt Comments for Slc1a2    GLT1: an integral membrane protein belonging to the sodium:dicarboxylate (SDF) symporter family. Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by co-transporting sodium.

Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Cellular Component: axolemma; axon; cell surface; dendritic shaft; dendritic spine; integral to membrane; integral to plasma membrane; membrane; neuron projection; plasma membrane; presynaptic membrane; synapse

Molecular Function: anion transmembrane transporter activity; glutamate:sodium symporter activity; high-affinity glutamate transmembrane transporter activity; L-glutamate transmembrane transporter activity; sodium:dicarboxylate symporter activity; symporter activity

Biological Process: adult behavior; cellular response to extracellular stimulus; dicarboxylic acid transport; L-glutamate import; L-glutamate transport; multicellular organism growth; multicellular organismal aging; nervous system development; positive regulation of glucose import; response to amino acid stimulus; response to drug; response to light stimulus; response to wounding; telencephalon development; transport; visual behavior
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Product References and Citations for Slc1a2 recombinant protein

   Mouse excitatory amino acid transporter EAAT2 isolation, characterization, and proximity to neuroexcitability loci on mouse chromosome 2.Kirschner M.A., Copeland N.G., Gilbert D.J., Jenkins N.A., Amara S.G.Genomics 24:218-224(1994) Molecular cloning of two glutamate transporter subtypes from mouse brain.Mukainaka Y., Tanaka K., Hagiwara T., Wada K.Biochim. Biophys. Acta 1244:233-237(1995) Molecular characterization of a high-affinity mouse glutamate transporter.Sutherland M.L., Delaney T.A., Noebels J.L.Gene 162:271-274(1995) Peng J.-B., Guo L.-H. Tissue specific variants of glutamate transporter GLT-1.Utsunomiya-Tate N., Endou H., Kanai Y.FEBS Lett. 416:312-316(1997) Lubec G., Kang S.U.Submitted (APR-2007) to UniProtKB Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.J. Proteome Res. 7:311-318(2008) Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease.Huang K., Kang M.H., Askew C., Kang R., Sanders S.S., Wan J., Davis N.G., Hayden M.R.Neurobiol. Dis. 40:207-215(2010)
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 Research Articles on Slc1a2    1. we have demonstrated for the first time that DOR receptor activation induces astrocytic expression of EAAT1 and EAAT2
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Slc1a2 recombinant proteinPathways associated with Slc1a2 recombinant protein
 Reference Product  PubMed Publications
 Tnf recombinant protein  >9 publications with Slc1a2 and Tnf
 Casp3 recombinant protein  >8 publications with Slc1a2 and Casp3
 Mtdh recombinant protein  >3 publications with Slc1a2 and Mtdh
 Gpr30 recombinant protein  >3 publications with Slc1a2 and Gpr30
 Slc6a1 recombinant protein  >2 publications with Slc1a2 and Slc6a1
 Adora1 recombinant protein  >2 publications with Slc1a2 and Adora1
 Slc29a1 recombinant protein  >2 publications with Slc1a2 and Slc29a1
 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Astrocytic Glutamate-Glutamine Uptake And Metabolism Pathway antibodies  Astrocytic Glutamate-Glutamine Uptake And Metabolism Pathway Diagram
 Glutamate Neurotransmitter Release Cycle Pathway antibodies  Glutamate Neurotransmitter Release Cycle Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Release Cycle Pathway antibodies  Neurotransmitter Release Cycle Pathway Diagram
 Neurotransmitter Uptake And Metabolism In Glial Cells Pathway antibodies  Neurotransmitter Uptake And Metabolism In Glial Cells Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
Diseases associated with Slc1a2 recombinant proteinOrgans/Tissues associated with Slc1a2 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >157 publications with Slc1a2 and Nervous System Diseases
 Brain Diseases Antibodies  >101 publications with Slc1a2 and Brain Diseases
 Disease Models, Animal Antibodies  >60 publications with Slc1a2 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >29 publications with Slc1a2 and Cardiovascular Diseases
 Amyotrophic Lateral Sclerosis Antibodies  >29 publications with Slc1a2 and Amyotrophic Lateral Sclerosis
 Epilepsy Antibodies  >22 publications with Slc1a2 and Epilepsy
 Movement Disorders Antibodies  >21 publications with Slc1a2 and Movement Disorders
 Pain Antibodies  >16 publications with Slc1a2 and Pain
 Necrosis Antibodies  >14 publications with Slc1a2 and Necrosis
 Inflammation Antibodies  >13 publications with Slc1a2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >240 publications with Slc1a2 and Brain
 Spinal Cord Antibodies  >39 publications with Slc1a2 and Spinal Cord
 Liver Antibodies  >10 publications with Slc1a2 and Liver
 Eye Antibodies  >6 publications with Slc1a2 and Eye
 Embryonic Tissue Antibodies  >5 publications with Slc1a2 and Embryonic Tissue
 Spleen Antibodies  >2 publications with Slc1a2 and Spleen
 Pituitary Gland Antibodies  >1 publications with Slc1a2 and Pituitary Gland
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