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FGF21 recombinant protein :: FGF-21 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS637422 FGF21 recombinant protein
Unit / Price
0.01 mg  /  $440 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FGF-21 (FGF21), Recombinant Protein

 Also Known As   

FGF-21, Recombinant, Human (His) (Fibroblast Growth Factor 21)

 Product Gene Name   

FGF21 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    Human FGF-21 (aa 1-209) is fused at the C-terminus to a His-tag.
 Chromosome Location    Chromosome: 19; NC_000019.9 (49258816..49261587). Location: 19q13.33
 OMIM    609436
 3D Structure    ModBase 3D Structure for Q9NSA1
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 Host    Human, HEK 293 cells
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 Purity/Purification    Highly Purified
>90% (SDS-PAGE)
 Form/Format    Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
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 Preparation and Storage    Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Working aliquots are stable for up to 3 months when stored at -20 degree C.
 Other Notes    Small volumes of FGF21 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for FGF21 recombinant protein

   FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.
 Product Categories/Family for FGF21 recombinant protein    Growth Factors, Cytokines; Growth Factors-FGF
NCBI/Uniprot data below describe general gene information for FGF21. It may not necessarily be applicable to this product.
 NCBI GI #    9506597
 NCBI GeneID    26291
 NCBI Accession #    NP_061986.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_019113.2 [Other Products]
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 UniProt Primary Accession #    Q9NSA1 [Other Products]
 UniProt Secondary Accession #    Q8N683 [Other Products]
 UniProt Related Accession #    Q9NSA1 [Other Products]
 Molecular Weight    ~22kD (SDS-PAGE) [Similar Products]
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 NCBI Official Full Name    fibroblast growth factor 21
 NCBI Official Synonym Full Names    fibroblast growth factor 21
 NCBI Official Symbol    FGF21 [Similar Products]
 NCBI Protein Information    fibroblast growth factor 21; FGF-21
 UniProt Protein Name    Fibroblast growth factor 21
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    FGF21 [Similar Products]
 UniProt Synonym Gene Names    FGF-21 [Similar Products]
 UniProt Entry Name    FGF21_HUMAN
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 NCBI Summary for FGF21    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FGF21    FGF21: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Belongs to the heparin-binding growth factors family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular region

Molecular Function: protein binding; growth factor activity; fibroblast growth factor receptor binding

Biological Process: positive regulation of glucose import; cell-cell signaling; positive regulation of cell proliferation; positive regulation of low-density lipoprotein receptor biosynthetic process; signal transduction
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 Research Articles on FGF21    1. FGF-21 mRNA is increased in skeletal muscle in HIV patients and correlates to whole-body (primarily reflecting muscle) insulin resistance, but not to plasma FGF-21
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FGF21 recombinant proteinPathways associated with FGF21 recombinant protein
 Reference Product  PubMed Publications
 PPARG recombinant protein  >28 publications with FGF21 and PPARG
 FGFR1 recombinant protein  >27 publications with FGF21 and FGFR1
 KLB recombinant protein  >23 publications with FGF21 and KLB
 FGFR4 recombinant protein  >13 publications with FGF21 and FGFR4
 FGFR2 recombinant protein  >7 publications with FGF21 and FGFR2
 AKT1 recombinant protein  >5 publications with FGF21 and AKT1
 FGFR3 recombinant protein  >4 publications with FGF21 and FGFR3
 CYP7A1 recombinant protein  >3 publications with FGF21 and CYP7A1
 INS recombinant protein  >1 publications with FGF21 and INS
 Products by Pathway  Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Melanoma Pathway antibodies  Melanoma Pathway Diagram
 Melanoma Pathway antibodies  Melanoma Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Proteoglycans In Cancer Pathway antibodies  Proteoglycans In Cancer Pathway Diagram
 Proteoglycans In Cancer Pathway antibodies  Proteoglycans In Cancer Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
Diseases associated with FGF21 recombinant proteinOrgans/Tissues associated with FGF21 recombinant protein
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >102 publications with FGF21 and Insulin Resistance
 Fatty Liver Antibodies  >99 publications with FGF21 and Fatty Liver
 Liver Diseases Antibodies  >55 publications with FGF21 and Liver Diseases
 Diabetes Mellitus, Type 2 Antibodies  >51 publications with FGF21 and Diabetes Mellitus, Type 2
 Inflammation Antibodies  >29 publications with FGF21 and Inflammation
 Hyperglycemia Antibodies  >26 publications with FGF21 and Hyperglycemia
 Weight Loss Antibodies  >25 publications with FGF21 and Weight Loss
 Non-alcoholic Fatty Liver Disease Antibodies  >21 publications with FGF21 and Non-alcoholic Fatty Liver Disease
 Cardiovascular Diseases Antibodies  >20 publications with FGF21 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >17 publications with FGF21 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with FGF21 and Lung
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