Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow FGF23  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • S100A8 Recombinant Protein
 • ARG2 ELISA Kit
 • CD178 Antibody
 • BACH1 Antibody
 • Clostridium difficile Toxin B Antibody
 • HIV-1 p55 gag Recombinant Protein
 • FKBP3 Recombinant Protein
 • ACADM Antibody
 • Anti-Thrombopoietin Antibody (anti-TPO Ab) ELISA Kit
 • Calmodulin regulated spectrin associated protein 2 (CAMSAP1L... ELISA Kit
 • Tumor Necrosis Factor alpha Human (tnfa) Recombinant Protein
 • PAR2 Antibody
 • Free Triiodothyronine (fT3) ELISA Kit
 • B2M - Beta 2 Microglobulin Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

FGF23 recombinant protein :: FGF-23 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS695607 FGF23 recombinant protein
Unit / Price
0.005 mg  /  $125 +1 FREE 8GB USB
0.02 mg  /  $195 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FGF-23 (FGF23), Recombinant Protein

★Popular Item★
 Also Known As   

Murine FGF-23

 Product Gene Name   

FGF23 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    phenotype 605380
Section Bar
 Species Reactivity    Species Reactivity: Mouse
Section Bar
Section Bar
 Preparation and Storage    -20 Degree C
 Other Notes    Small volumes of FGF23 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for FGF23. It may not necessarily be applicable to this product.
 NCBI GI #    10190674
 NCBI GeneID    8074
 NCBI Accession #    NP_065689.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020638.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q4V758 [Other Products]
 UniProt Related Accession #    Q9GZV9 [Other Products]
 Molecular Weight    27,954 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    fibroblast growth factor 23
 NCBI Official Synonym Full Names    fibroblast growth factor 23
 NCBI Official Symbol    FGF23 [Similar Products]
 NCBI Official Synonym Symbols   
ADHR; FGFN; HYPF; HPDR2; PHPTC
[Similar Products]
 NCBI Protein Information    fibroblast growth factor 23; phosphatonin; tumor-derived hypophosphatemia inducing factor
 UniProt Protein Name    Fibroblast growth factor 23
 UniProt Synonym Protein Names   
Phosphatonin; Tumor-derived hypophosphatemia-inducing factorCleaved into the following 2 chains:Fibroblast growth factor 23 N-terminal peptide; Fibroblast growth factor 23 C-terminal peptide
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    FGF23 [Similar Products]
 UniProt Synonym Gene Names    HYPF; FGF-23 [Similar Products]
 UniProt Entry Name    FGF23_HUMAN
Section Bar
 NCBI Summary for FGF23    This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]
Section Bar
 UniProt Comments for FGF23    FGF23: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR). ADHR is characterized by low serum phosphorus concentrations, rickets, osteomalacia, leg deformities, short stature, bone pain and dental abscesses. Defects in FGF23 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC). HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: extracellular space; extracellular region

Molecular Function: growth factor activity; type 1 fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of bone mineralization; fibroblast growth factor receptor signaling pathway; cellular phosphate ion homeostasis; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; negative regulation of hormone secretion; positive regulation of transcription, DNA-dependent; insulin receptor signaling pathway; innate immune response; negative regulation of osteoblast differentiation; phosphate ion homeostasis; cell differentiation; phosphate metabolic process; vitamin D catabolic process

Disease: Hypophosphatemic Rickets, Autosomal Dominant
Table BarTOPTable Bar
 Research Articles on FGF23    1. We report on a novel association between low FGF23 and CVD in chronic HD patients and a lack of correlation of FGF-23 with VC. FGF-23 could play a role in cardiovascular protection that remains to be confirmed in larger studies.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with FGF23 recombinant proteinPathways associated with FGF23 recombinant protein
 Reference Product  PubMed Publications
 PTH recombinant protein  >266 publications with FGF23 and PTH
 PHEX recombinant protein  >104 publications with FGF23 and PHEX
 FGFR1 recombinant protein  >52 publications with FGF23 and FGFR1
 GALNT3 recombinant protein  >46 publications with FGF23 and GALNT3
 MEPE recombinant protein  >28 publications with FGF23 and MEPE
 FGFR3 recombinant protein  >14 publications with FGF23 and FGFR3
 FGFR4 recombinant protein  >11 publications with FGF23 and FGFR4
 FGFR2 recombinant protein  >10 publications with FGF23 and FGFR2
 FGF1 recombinant protein  >7 publications with FGF23 and FGF1
 Products by Pathway  Pathway Diagram
 Activated Point Mutants Of FGFR2 Pathway antibodies  Activated Point Mutants Of FGFR2 Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
Diseases associated with FGF23 recombinant proteinOrgans/Tissues associated with FGF23 recombinant protein
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >437 publications with FGF23 and Kidney Diseases
 Rickets Antibodies  >267 publications with FGF23 and Rickets
 Phosphorus Metabolism Disorders Antibodies  >261 publications with FGF23 and Phosphorus Metabolism Disorders
 Renal Insufficiency Antibodies  >202 publications with FGF23 and Renal Insufficiency
 Hyperphosphatemia Antibodies  >153 publications with FGF23 and Hyperphosphatemia
 Calcinosis Antibodies  >116 publications with FGF23 and Calcinosis
 Hyperparathyroidism, Secondary Antibodies  >106 publications with FGF23 and Hyperparathyroidism, Secondary
 Hypertension Antibodies  >69 publications with FGF23 and Hypertension
 Hypophosphatemic Rickets, Autosomal Dominant Antibodies  >64 publications with FGF23 and Hypophosphatemic Rickets, Autosomal Dominant
 Hypertrophy Antibodies  >44 publications with FGF23 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >13 publications with FGF23 and Embryonic Tissue
 Testis Antibodies  >2 publications with FGF23 and Testis
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions