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FABP3 recombinant protein :: Fatty acid-binding protein Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS960767
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fatty acid-binding protein (FABP3), Recombinant Protein

 Also Known As   

Recombinant Human Fatty acid-binding protein, heart

 Product Synonym Names    Fatty acid-binding protein 3; H-FABP; Mammary-derived growth inhibitor; Muscle fatty acid-binding protein; MDGI; M-FABP
 Product Gene Name   

FABP3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-133
 Sequence    MVDAFLGTWK LVDSKNFDDY MKSLGVGFAT RQVASMTKPT TIIEKNGDIL TLKTHSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHLQKWDG QETTLVRELI DGKLILTLTH GTAVCTRTYE KEA
 OMIM    134651
 3D Structure    ModBase 3D Structure for P05413
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE.
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of FABP3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for FABP3 recombinant protein

   FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
 Product Categories/Family for FABP3 recombinant protein    Transport
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 SDS-Page of FABP3 recombinant protein    FABP3 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for FABP3. It may not necessarily be applicable to this product.
 NCBI GI #    4758328
 NCBI GeneID    2170
 NCBI Accession #    NP_004093.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004102.3 [Other Products]
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 UniProt Primary Accession #    P05413 [Other Products]
 UniProt Secondary Accession #    Q5VV93; Q99957; B2RAB6 [Other Products]
 UniProt Related Accession #    P05413 [Other Products]
 Molecular Weight    18.8kD
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 NCBI Official Full Name    fatty acid-binding protein, heart
 NCBI Official Synonym Full Names    fatty acid binding protein 3
 NCBI Official Symbol    FABP3 [Similar Products]
 NCBI Official Synonym Symbols   
MDGI; FABP11; H-FABP; M-FABP; O-FABP
[Similar Products]
 NCBI Protein Information    fatty acid-binding protein, heart
 UniProt Protein Name    Fatty acid-binding protein, heart
 UniProt Synonym Protein Names   
Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; M-FABP
 Protein Family    Fatty acid-binding protein
 UniProt Gene Name    FABP3 [Similar Products]
 UniProt Synonym Gene Names    FABP11; MDGI; H-FABP; MDGI; M-FABP [Similar Products]
 UniProt Entry Name    FABPH_HUMAN
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 NCBI Summary for FABP3    The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FABP3    FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 1p33-p32

Cellular Component: cytosol; extracellular space; sarcoplasm

Molecular Function: cytoskeletal protein binding; icosatetraenoic acid binding; long-chain fatty acid transporter activity; protein binding

Biological Process: cholesterol homeostasis; fatty acid metabolic process; negative regulation of cell proliferation; phospholipid homeostasis; regulation of fatty acid oxidation; response to drug; response to insulin stimulus; triacylglycerol catabolic process
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Product References and Citations for FABP3 recombinant protein

   The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project Team Genome Res. 14:2121-2127(2004) The major protein expression profile and two-dimensional protein database of human heart.Kovalyov L.I., Shishkin S.S., Efimochkin A.S., Kovalyova M.A., Ershova E.S., Egorov T.A., Musalyamov A.K.Electrophoresis 16:1160-1169(1995)
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 Research Articles on FABP3    1. H-FABP may have a role in occurrence of adverse clinical outcome in pulmonary embolism [meta-analysis]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FABP3 recombinant proteinPathways associated with FABP3 recombinant protein
 Reference Product  PubMed Publications
 FABP1 recombinant protein  >19 publications with FABP3 and FABP1
 LPIN1 recombinant protein  >6 publications with FABP3 and LPIN1
 ACSL1 recombinant protein  >4 publications with FABP3 and ACSL1
 FAAH recombinant protein  >2 publications with FABP3 and FAAH
 SLC27A6 recombinant protein  >2 publications with FABP3 and SLC27A6
 SIRT1 recombinant protein  >2 publications with FABP3 and SIRT1
 Products by Pathway  Pathway Diagram
 Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway antibodies  Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
Diseases associated with FABP3 recombinant proteinOrgans/Tissues associated with FABP3 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >176 publications with FABP3 and Cardiovascular Diseases
 Heart Diseases Antibodies  >147 publications with FABP3 and Heart Diseases
 Myocardial Infarction Antibodies  >82 publications with FABP3 and Myocardial Infarction
 Nervous System Diseases Antibodies  >66 publications with FABP3 and Nervous System Diseases
 Fatty Liver Antibodies  >36 publications with FABP3 and Fatty Liver
 Necrosis Antibodies  >33 publications with FABP3 and Necrosis
 Inflammation Antibodies  >22 publications with FABP3 and Inflammation
 Disease Models, Animal Antibodies  >20 publications with FABP3 and Disease Models, Animal
 Breast Neoplasms Antibodies  >16 publications with FABP3 and Breast Neoplasms
 Hypertension Antibodies  >13 publications with FABP3 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >264 publications with FABP3 and Heart
 Muscle Antibodies  >127 publications with FABP3 and Muscle
 Brain Antibodies  >91 publications with FABP3 and Brain
 Liver Antibodies  >38 publications with FABP3 and Liver
 Kidney Antibodies  >27 publications with FABP3 and Kidney
 Connective Tissue Antibodies  >24 publications with FABP3 and Connective Tissue
 Embryonic Tissue Antibodies  >13 publications with FABP3 and Embryonic Tissue
 Lung Antibodies  >12 publications with FABP3 and Lung
 Placenta Antibodies  >10 publications with FABP3 and Placenta
 Bone Antibodies  >5 publications with FABP3 and Bone
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