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FuR recombinant protein :: Ferric uptake regulator (FuR) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS203197
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ferric uptake regulator (FuR), Recombinant Protein

★Popular Item★
 Also Known As   

Ferric uptake regulator (FuR), 1-148aa, E Coli, E Coli

 Product Synonym Names    DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport; Ferric uptake regulator; FuR; ECK0671; Ferric uptake regulation protein; JW0669.
 Product Gene Name   

FuR recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MTDNNTALKK AGLKVTLPRL KILEVLQEPD NHHVSAEDLY KRLIDMGEEI GLATVYRVLN QFDDAGIVTR HNFEGGKSVF ELTQQHHHDH LICLDCGKVI EFSDDSIEAR QREIAAKHGI RLTNHSLYLY GHCAEGDCRE DEHAHEGK
 3D Structure    ModBase 3D Structure for P0A9A9
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 Host    E Coli
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 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid in 20mM Tris pH 8.0, 2mM CaCl2, 100mM NaCl
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of FuR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for FuR recombinant protein

   Fur (ferric uptake regulator) protein is a DNA-binding protein which regulates iron-responsive genes. Fur is a small, 17-kDa, global transcriptional repressor that in the presence of iron regulates functions as diverse as iron acquisition, oxidative stress, and virulence. In Escherichia coli, members of the Fur family regulate the expression of more than 100 genes that function in processes as varied as the biosynthesis and transport of siderophores, the expression of virulence factors, the alleviation of oxidative and NO-induced stress, and the inhibition of ferritin production through the expression of RyhB. Recombinant FuR was expressed in E Coli and purified by using conventional chromatography techniques.
 Product Categories/Family for FuR recombinant protein    Cell Cycle
 Applications Tested/Suitable for FuR recombinant protein   

SDS-PAGE

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 SDS-Page of FuR recombinant protein    FuR recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for FuR. It may not necessarily be applicable to this product.
 NCBI GI #    16128659
 NCBI GeneID    945295
 NCBI Accession #    NP_415209 [Other Products]
 NCBI GenBank Nucleotide #    NC_000913.3 [Other Products]
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 UniProt Primary Accession #    P0A9A9 [Other Products]
 UniProt Secondary Accession #    P06975 [Other Products]
 Molecular Weight    16.7kDa (148aa), confirmed by MALDI-TOF.
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 NCBI Official Full Name    ferric iron uptake regulon transcriptional repressor; autorepressor
 NCBI Official Symbol    fur [Similar Products]
 NCBI Official Synonym Symbols   
ECK0671; JW0669
[Similar Products]
 NCBI Protein Information    ferric iron uptake regulon transcriptional repressor; autorepressor
 UniProt Protein Name    Ferric uptake regulation protein
 Protein Family    Ferric uptake regulation protein
 UniProt Gene Name    fur [Similar Products]
 UniProt Synonym Gene Names    Ferric uptake regulator [Similar Products]
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 NCBI Summary for FuR    Fur translation in coupled to the translation of the upstream leader pepidie Uof; Uof translation is inhibited by the antisense sRNA ryhB; Uof translation opens up a hairpin that blocks Fur translation (Vecerek, 2007). [More information is available at EcoGene: EG10359].
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 UniProt Comments for FuR    Acts as a global negative controlling element, employing Fe2+ as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon.
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Product References and Citations for FuR recombinant protein

   O'Sullivan DJ., et al. (1994). FEMS Microbiol Lett. Apr 15; 117 (3):327-32; Mills SA., et al. (2005) Biochemistry. Oct 18; 44 (41):13553-9;
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 Research Articles on FuR    1. The authors report that O2 availability affects the gene expression programs of two Escherichia coli master regulators that function in iron homeostasis: the transcription factor Fur and the small RNA regulator RyhB.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FuR recombinant protein
 Reference Product  PubMed Publications
 hemE recombinant protein  >917 publications with FuR and hemE
 spoT recombinant protein  >581 publications with FuR and spoT
 katE recombinant protein  >189 publications with FuR and katE
 sodA recombinant protein  >79 publications with FuR and sodA
 sodB recombinant protein  >51 publications with FuR and sodB
 polA recombinant protein  >19 publications with FuR and polA
 feoB recombinant protein  >15 publications with FuR and feoB
 fldA recombinant protein  >10 publications with FuR and fldA
 fumC recombinant protein  >9 publications with FuR and fumC
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