Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow FTH1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Abz-Gly-Phe(NO2)-Pro-OH Enzyme Substrate
 • Anti-IgA Antibody ELISA Kit
 • Pectinase (PG2) Enzyme
 • LILRB4 Antibody
 • Cys-C (Cystatin C) CLIA Kit
 • Erk1-2-T202-Y204 (MAPK1-ERK2, MAPK3-ERK1) Antibody
 • NFH Antibody
 • BGLAP Antibody
 • Dipeptidyl peptidase 4 (DPP4) ELISA Kit
 • SLC24A5 (SLC24A5 ) Antibody
 • Mast cell tryptase (MCT) ELISA Kit
 • WASF1 - WAVE Peptide
 • Retinoic acid receptor responder protein 1 (RARRES1) Recombinant Protein
 • Carbohydrate Sulfotransferase 5 (CHST5) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

FTH1 recombinant protein :: Ferritin Heavy Chain Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS143428 FTH1 recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.025 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $3,515 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ferritin Heavy Chain (FTH1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Ferritin Heavy Chain

 Product Synonym Names    Ferritin heavy chain, Cell proliferation-inducing gene 15 protein, FTH1, FHC, FTH, PLIF, FTHL6, PIG15, MGC104426
 Product Gene Name   

FTH1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK NFAKYFLHQS HEEREHAEKL MKLQNQRGGR IFLQDIKKPD CDDWESGLNA MECALHLEKN VNQSLLELHK LATDKNDPHL CDFIETHYLN EQVKAIKELG DHVTNLRKMG APESGLAEYL FDKHTLGDSD NES
 OMIM    134770
 3D Structure    ModBase 3D Structure for P02794
Section Bar
Section Bar
 Purity/Purification    Greater than 95.0% as determined by SDS-PAGE.
 Form/Format    The FTH1 protein solution (1 mg/mL) contains 20mM Tris-HCl pH-7.5, 1mM DTT and 10% glycerol.
Section Bar
 Source    E.coli
 Physical Appearance    Sterile Filtered colorless solution.
Section Bar
 Preparation and Storage    Store at 4C if entire vial will be used within 2-4 weeks.
Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of FTH1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for FTH1 recombinant protein

   Description: FTH1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 183 amino acids and having a molecular mass of 21 kDa.

Introduction: Ferritin is a fairly large, iron-storage heteropolymeric protein composed of 2 subunit types, light Ferritin & heavy Ferritin polypeptides, which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin is composed of 24 self-assembled polypeptide subunits of the heavy and light ferritin chains and is characterized by the capacity to remove Fe (II) from solution in the presence of oxygen. Ferritin light polypeptide protein is the main intracellular iron storage protein in prokaryotes and eukaryotes. Variation in ferritin subunit composition influence the rates of iron uptake and release in various tissues. A key function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyper ferrit anemia-cataract syndrome. Ferritin stores iron in a soluble, nontoxic, readily accessible form. Ferritin is needed for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after it has been oxidized.
 Product Categories/Family for FTH1 recombinant protein    RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Ferritin
NCBI/Uniprot data below describe general gene information for FTH1. It may not necessarily be applicable to this product.
 NCBI GI #    56682959
 NCBI GeneID    2495
 NCBI Accession #    NP_002023.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002032.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P02794 [Other Products]
 UniProt Secondary Accession #    Q3KRA8; Q3SWW1; B3KNR5 [Other Products]
 UniProt Related Accession #    P02794 [Other Products]
Table BarTOPTable Bar
 NCBI Official Full Name    ferritin heavy chain
 NCBI Official Synonym Full Names    ferritin, heavy polypeptide 1
 NCBI Official Symbol    FTH1 [Similar Products]
 NCBI Official Synonym Symbols   
FHC; FTH; HFE5; PLIF; FTHL6; PIG15
[Similar Products]
 NCBI Protein Information    ferritin heavy chain; apoferritin; cell proliferation-inducing gene 15 protein; ferritin H subunit; placenta immunoregulatory factor; proliferation-inducing protein 15
 UniProt Protein Name    Ferritin heavy chain
 UniProt Synonym Protein Names   
Cell proliferation-inducing gene 15 proteinFerritin heavy chain, N-terminally processed
 Protein Family    Ferritin
 UniProt Gene Name    FTH1 [Similar Products]
 UniProt Synonym Gene Names    FTH; FTHL6; Ferritin H subunit [Similar Products]
 UniProt Entry Name    FRIH_HUMAN
Section Bar
 NCBI Summary for FTH1    This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for FTH1    Ferritin-H: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited. Belongs to the ferritin family.

Protein type: EC 1.16.3.1; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Oxidoreductase

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: ferritin complex; mitochondrion; cytosol; nucleus

Molecular Function: ferroxidase activity; protein binding; ferric iron binding; iron ion binding

Biological Process: negative regulation of cell proliferation; receptor-mediated endocytosis; negative regulation of fibroblast proliferation; cellular iron ion homeostasis; immune response; post-Golgi vesicle-mediated transport; transmembrane transport; iron ion transport; intracellular sequestering of iron ion

Disease: Hemochromatosis, Type 5
Table BarTOPTable Bar
 Research Articles on FTH1    1. High serum ferritin levels are associated with pancreatic cancer.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with FTH1 recombinant proteinPathways associated with FTH1 recombinant protein
 Reference Product  PubMed Publications
 FTL recombinant protein  >12 publications with FTH1 and FTL
 TFRC recombinant protein  >3 publications with FTH1 and TFRC
 FECH recombinant protein  >2 publications with FTH1 and FECH
 ACO1 recombinant protein  >1 publications with FTH1 and ACO1
 MAX recombinant protein  >1 publications with FTH1 and MAX
 MYC recombinant protein  >1 publications with FTH1 and MYC
 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Iron Metabolism In Placenta Pathway antibodies  Iron Metabolism In Placenta Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Scavenging By Class A Receptors Pathway antibodies  Scavenging By Class A Receptors Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with FTH1 recombinant proteinOrgans/Tissues associated with FTH1 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5 publications with FTH1 and Inflammation
 Nervous System Diseases Antibodies  >5 publications with FTH1 and Nervous System Diseases
 Liver Diseases Antibodies  >4 publications with FTH1 and Liver Diseases
 Brain Diseases Antibodies  >4 publications with FTH1 and Brain Diseases
 Iron Overload Antibodies  >4 publications with FTH1 and Iron Overload
 Nerve Degeneration Antibodies  >2 publications with FTH1 and Nerve Degeneration
 Neurodegenerative Diseases Antibodies  >2 publications with FTH1 and Neurodegenerative Diseases
 Weight Loss Antibodies  >1 publications with FTH1 and Weight Loss
 Edema Antibodies  >1 publications with FTH1 and Edema
 Fatty Liver Antibodies  >1 publications with FTH1 and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13 publications with FTH1 and Blood
 Brain Antibodies  >9 publications with FTH1 and Brain
 Liver Antibodies  >8 publications with FTH1 and Liver
 Nerve Antibodies  >8 publications with FTH1 and Nerve
 Placenta Antibodies  >4 publications with FTH1 and Placenta
 Bone Antibodies  >4 publications with FTH1 and Bone
 Spleen Antibodies  >3 publications with FTH1 and Spleen
 Vascular Antibodies  >3 publications with FTH1 and Vascular
 Bone Marrow Antibodies  >3 publications with FTH1 and Bone Marrow
 Lung Antibodies  >3 publications with FTH1 and Lung
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions