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Fth1 recombinant protein :: Ferritin heavy chain (Fth1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1110794 Fth1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $580 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $775 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $855 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $885 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $995 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,115 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,115 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,120 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,205 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,610 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,690 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,710 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,155 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ferritin heavy chain (Fth1), Recombinant Protein

 Also Known As   

Recombinant Rat Ferritin heavy chain (Fth1)

 Product Gene Name   

Fth1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-182aa, full length protein
 Sequence    MTTASPSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSC YFDRDDVALK NFAKYFLHQS HEEREHAEKL MKLQNQRGGR IFLQDIKKPD RDDWESGLNA MRCALHLEKS VNQSLLELHK LATDKNDPHL CDFIETHYLN EQVKSIKELG DHVTNLRKMG APESGMAEYL FDKHTLGHGD ES
 3D Structure    ModBase 3D Structure for P19132
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Fth1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Fth1 recombinant protein

   This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
NCBI/Uniprot data below describe general gene information for Fth1. It may not necessarily be applicable to this product.
 NCBI GI #    6978859
 NCBI GeneID    25319
 NCBI Accession #    NP_036980.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012848.2 [Other Products]
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 UniProt Primary Accession #    P19132 [Other Products]
 UniProt Related Accession #    P19132 [Other Products]
 Molecular Weight    21,127 Da
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 NCBI Official Full Name    ferritin heavy chain
 NCBI Official Synonym Full Names    ferritin heavy chain 1
 NCBI Official Symbol    Fth1 [Similar Products]
 NCBI Official Synonym Symbols   
Fth
[Similar Products]
 NCBI Protein Information    ferritin heavy chain
 UniProt Protein Name    Ferritin heavy chain
 Protein Family    Iron transporter
 UniProt Gene Name    Fth1 [Similar Products]
 UniProt Synonym Gene Names    Fth; Ferritin H subunit [Similar Products]
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 NCBI Summary for Fth1    overexpressed during hepatic tumor development; used as an early marker for hepatocellular carcinoma [RGD, Feb 2006]
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 UniProt Comments for Fth1    Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney ().
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 Research Articles on Fth1    1. This work demonstrates the key role of the cytokine IL-1beta in the regulation of a novel intracellular mediator [i.e., the protein ferritin heavy chain (FHC)] of HIV-induced dendritic damage and the resulting neurocognitive impairment.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Fth1 recombinant proteinPathways associated with Fth1 recombinant protein
 Reference Product  PubMed Publications
 Fech recombinant protein  >2 publications with Fth1 and Fech
 Hint1 recombinant protein  >1 publications with Fth1 and Hint1
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 NFE2L2 Pathway antibodies  NFE2L2 Pathway Diagram
 Neutrophil Degranulation Pathway antibodies  Neutrophil Degranulation Pathway Diagram
Diseases associated with Fth1 recombinant proteinOrgans/Tissues associated with Fth1 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >8 publications with Fth1 and Inflammation
 Liver Diseases Antibodies  >7 publications with Fth1 and Liver Diseases
 Nervous System Diseases Antibodies  >7 publications with Fth1 and Nervous System Diseases
 Brain Diseases Antibodies  >6 publications with Fth1 and Brain Diseases
 Breast Neoplasms Antibodies  >5 publications with Fth1 and Breast Neoplasms
 Iron Overload Antibodies  >4 publications with Fth1 and Iron Overload
 Necrosis Antibodies  >3 publications with Fth1 and Necrosis
 Neurodegenerative Diseases Antibodies  >3 publications with Fth1 and Neurodegenerative Diseases
 Fatty Liver Antibodies  >2 publications with Fth1 and Fatty Liver
 Liver Neoplasms Antibodies  >2 publications with Fth1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >11 publications with Fth1 and Liver
 Placenta Antibodies  >5 publications with Fth1 and Placenta
 Heart Antibodies  >3 publications with Fth1 and Heart
 Embryonic Tissue Antibodies  >2 publications with Fth1 and Embryonic Tissue
 Ovary Antibodies  >1 publications with Fth1 and Ovary
 Testis Antibodies  >1 publications with Fth1 and Testis
 Pituitary Gland Antibodies  >1 publications with Fth1 and Pituitary Gland
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