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FBN2 recombinant protein :: Fibrillin-2 (FBN2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS964380 FBN2 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $905 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $905 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,130 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,130 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,280 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,280 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,745 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,745 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,780 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,525 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fibrillin-2 (FBN2), Recombinant Protein

 Also Known As   

Recombinant Human Fibrillin-2 (FBN2) , partial

 Product Gene Name   

FBN2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2780-2912, Fragment at the C-terminal.
 Sequence    SIHEPDPTAV EQISLESVDM DSPVNMKFNL SHLGSKEHIL ELRPAIQPLN NHIRYVISQG NDDSVFRIHQ RNGLSYLHTA KKKLMPGTYT LEITSIPLYK KKELKKLEES NEDDYLLGEL GEALRMRLQI QLY
 OMIM    121050
 3D Structure    ModBase 3D Structure for P35556
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of FBN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for FBN2 recombinant protein

   This protein is a component of connective tissue microfibrils and may be involved in elastic fiber assembly. Mutations in this gene cause congenital contractural arachnodactyly.
NCBI/Uniprot data below describe general gene information for FBN2. It may not necessarily be applicable to this product.
 NCBI GI #    66346695
 NCBI GeneID    2201
 NCBI Accession #    NP_001990.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001999.3 [Other Products]
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 UniProt Primary Accession #    P35556 [Other Products]
 UniProt Secondary Accession #    Q59ES6; B4DU01 [Other Products]
 UniProt Related Accession #    P35556 [Other Products]
 Molecular Weight    157,690 Da
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 NCBI Official Full Name    fibrillin-2
 NCBI Official Synonym Full Names    fibrillin 2
 NCBI Official Symbol    FBN2 [Similar Products]
 NCBI Official Synonym Symbols   
CCA; DA9; EOMD
[Similar Products]
 NCBI Protein Information    fibrillin-2
 UniProt Protein Name    Fibrillin-2
 Protein Family    Fibrillin
 UniProt Gene Name    FBN2 [Similar Products]
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 NCBI Summary for FBN2    The protein encoded by this gene is a component of connective tissue microfibrils and may be involved in elastic fiber assembly. Mutations in this gene cause congenital contractural arachnodactyly. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FBN2    Fibrillin-2: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
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 Research Articles on FBN2    1. BAV patients have an increased FBN (especially FBN2) gene expression level in the ascending aorta, irrespective of dilatation, whereas MMP expression does not change significantly.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FBN2 recombinant proteinPathways associated with FBN2 recombinant protein
 Reference Product  PubMed Publications
 FBN1 recombinant protein  >31 publications with FBN2 and FBN1
 Products by Pathway  Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with FBN2 recombinant proteinOrgans/Tissues associated with FBN2 recombinant protein
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >34 publications with FBN2 and Congenital Abnormalities
 Cardiovascular Diseases Antibodies  >31 publications with FBN2 and Cardiovascular Diseases
 Abnormalities, Multiple Antibodies  >30 publications with FBN2 and Abnormalities, Multiple
 Congenital contractural arachnodactyly Antibodies  >30 publications with FBN2 and Congenital contractural arachnodactyly
 Nervous System Diseases Antibodies  >8 publications with FBN2 and Nervous System Diseases
 Colorectal Neoplasms Antibodies  >4 publications with FBN2 and Colorectal Neoplasms
 Brain Diseases Antibodies  >3 publications with FBN2 and Brain Diseases
 Liver Diseases Antibodies  >2 publications with FBN2 and Liver Diseases
 Kidney Diseases Antibodies  >2 publications with FBN2 and Kidney Diseases
 Liver Neoplasms Antibodies  >1 publications with FBN2 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >23 publications with FBN2 and Connective Tissue
 Skin Antibodies  >8 publications with FBN2 and Skin
 Muscle Antibodies  >7 publications with FBN2 and Muscle
 Embryonic Tissue Antibodies  >7 publications with FBN2 and Embryonic Tissue
 Bone Antibodies  >6 publications with FBN2 and Bone
 Ear Antibodies  >5 publications with FBN2 and Ear
 Eye Antibodies  >5 publications with FBN2 and Eye
 Lung Antibodies  >4 publications with FBN2 and Lung
 Kidney Antibodies  >4 publications with FBN2 and Kidney
 Blood Antibodies  >3 publications with FBN2 and Blood
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