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Fgf15 recombinant protein :: Fibroblast growth factor 15 (Fgf15) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1062537
SDS-PAGE
Unit / Price
0.05 mg (E-Coli)  /  $590 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $745 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $795 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $875 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $895 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,000 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,125 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,130 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,130 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,230 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,625 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,715 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,725 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,175 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fibroblast growth factor 15 (Fgf15), Recombinant Protein

 Also Known As   

Recombinant Mouse Fibroblast growth factor 15 (Fgf15)

 Product Synonym Names    Fibroblast growth factor 15; FGF-15
 Product Gene Name   

Fgf15 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1062537 COA    COA PDF
 Sequence Positions    26-218aa; Full Length of Mature Protein
 Sequence    RPLAQQSQSV SDEDPLFLYG WGKITRLQYL YSAGPYVSNC FLRIRSDGSV DCEEDQNERN LLEFRAVALK TIAIKDVSSV RYLCMSADGK IYGLIRYSEE DCTFREEMDC LGYNQYRSMK HHLHIIFIQA KPREQLQDQK PSNFIPVFHR SFFETGDQLR SKMFSLPLES DSMDPFRMVE DVDHLVKSPS FQK
 3D Structure    ModBase 3D Structure for O35622
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
 Production Note    Special Offer: The E. coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E. coli host-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E. coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E. coli host-expressed protein for the fastest delivery among all hosts. Please contact us or email to support@mybiosource.com for more details.
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Fgf15 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Fgf15 recombinant protein

   Fgf15
 Product Categories/Family for Fgf15 recombinant protein    Signal Transduction
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 SDS-PAGE of Fgf15 recombinant protein    Fgf15 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Fgf15. It may not necessarily be applicable to this product.
 NCBI GI #    6679777
 NCBI GeneID    14170
 NCBI Accession #    NP_032029.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_008003.2 [Other Products]
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 UniProt Primary Accession #    O35622 [Other Products]
 UniProt Related Accession #    O35622 [Other Products]
 Molecular Weight    25,236 Da
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 NCBI Official Full Name    fibroblast growth factor 15
 NCBI Official Synonym Full Names    fibroblast growth factor 15
 NCBI Official Symbol    Fgf15 [Similar Products]
 NCBI Official Synonym Symbols   
FGF19
[Similar Products]
 NCBI Protein Information    fibroblast growth factor 15; FGF-15
 UniProt Protein Name    Fibroblast growth factor 15
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    Fgf15 [Similar Products]
 UniProt Synonym Gene Names    FGF-15 [Similar Products]
 UniProt Entry Name    FGF15_MOUSE
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 UniProt Comments for Fgf15    FGF19: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. Belongs to the heparin-binding growth factors family.

Protein type: Motility/polarity/chemotaxis; Cell development/differentiation; Cytokine; Secreted, signal peptide; Secreted

Cellular Component: extracellular region

Molecular Function: protein binding; growth factor activity; receptor binding; fibroblast growth factor receptor binding

Biological Process: positive regulation of glucose import; fibroblast growth factor receptor signaling pathway; heart development; positive regulation of cell proliferation; positive regulation of JNK cascade; positive regulation of protein amino acid phosphorylation; neural crest cell migration
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 Research Articles on Fgf15    1. results suggest that FGF15 deficiency severely impairs liver regeneration in mice after PHx. The underlying mechanism is likely the result of disrupted bile acid homeostasis and impaired priming of hepatocyte proliferation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Fgf15 recombinant proteinPathways associated with Fgf15 recombinant protein
 Reference Product  PubMed Publications
 Cyp7a1 recombinant protein  >30 publications with Fgf15 and Cyp7a1
 Fgf8 recombinant protein  >12 publications with Fgf15 and Fgf8
 Fgfr4 recombinant protein  >12 publications with Fgf15 and Fgfr4
 Fgf23 recombinant protein  >7 publications with Fgf15 and Fgf23
 Fgf4 recombinant protein  >4 publications with Fgf15 and Fgf4
 Fgf17 recombinant protein  >4 publications with Fgf15 and Fgf17
 Fgf9 recombinant protein  >2 publications with Fgf15 and Fgf9
 Fgf6 recombinant protein  >1 publications with Fgf15 and Fgf6
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 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 ESC Pluripotency Pathways antibodies  ESC Pluripotency Pathways Diagram
 FGFR Ligand Binding And Activation Pathway antibodies  FGFR Ligand Binding And Activation Pathway Diagram
Diseases associated with Fgf15 recombinant proteinOrgans/Tissues associated with Fgf15 recombinant protein
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >6 publications with Fgf15 and Fatty Liver
 Disease Models, Animal Antibodies  >5 publications with Fgf15 and Disease Models, Animal
 Neoplasms Antibodies  >5 publications with Fgf15 and Neoplasms
 Obesity Antibodies  >5 publications with Fgf15 and Obesity
 Inflammation Antibodies  >5 publications with Fgf15 and Inflammation
 Liver Neoplasms Antibodies  >4 publications with Fgf15 and Liver Neoplasms
 Insulin Resistance Antibodies  >4 publications with Fgf15 and Insulin Resistance
 Drug-Induced Liver Injury Antibodies  >3 publications with Fgf15 and Drug-Induced Liver Injury
 Cholestasis Antibodies  >3 publications with Fgf15 and Cholestasis
 Heart Defects, Congenital Antibodies  >2 publications with Fgf15 and Heart Defects, Congenital
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >18 publications with Fgf15 and Brain
 Embryonic Tissue Antibodies  >10 publications with Fgf15 and Embryonic Tissue
 Eye Antibodies  >7 publications with Fgf15 and Eye
 Inner Ear Antibodies  >2 publications with Fgf15 and Inner Ear
 Spinal Cord Antibodies  >2 publications with Fgf15 and Spinal Cord
 Lung Antibodies  >1 publications with Fgf15 and Lung
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