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fbl-1 recombinant protein :: Fibulin-1 (fbl-1), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1214796 fbl-1 recombinant protein
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 Product Name   

Fibulin-1 (fbl-1), partial, Recombinant Protein

 Also Known As   

Recombinant Fibulin-1 (fbl-1), partial

 Product Synonym Names    Fibulin-1
 Product Gene Name   

fbl-1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    fbl-1; fbln1; F56H11.1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for O77469
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Caenorhabditis elegans
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of fbl-1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for fbl-1. It may not necessarily be applicable to this product.
 NCBI GI #    71989803
 NCBI GeneID    177788
 NCBI Accession #    NP_001023236.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001028065.2 [Other Products]
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 UniProt Primary Accession #    O77469 [Other Products]
 UniProt Secondary Accession #    O18026; O77474; Q20903; Q50JF9; Q5I5Q9; Q95NZ3; Q9TZS1 [Other Products]
 UniProt Related Accession #    CAA92962 [Other Products]
 Molecular Weight    74,625 Da
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 NCBI Official Full Name    Protein FBL-1, isoform a
 NCBI Official Symbol    fbl-1 [Similar Products]
 NCBI Protein Information    Protein FBL-1
 UniProt Protein Name    Fibulin-1
 Protein Family    Fibulin
 UniProt Gene Name    fbl-1 [Similar Products]
 UniProt Synonym Gene Names    fbln1 [Similar Products]
 UniProt Entry Name    FBLN1_CAEEL
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 UniProt Comments for fbl-1    Incorporated into fibronectin-containing matrix fibers. Plays a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Important for certain developmental processes and contributes to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Involved with gon-1 and mig-17 in distal tip cell (DTC) migration along the body wall basement membranes, a key step that promotes gonad morphogenesis. Has an antagonistic role with gon-1 and mig-17. Isoform a has roles in regulating the shape and adhesion of cells in the developing pharynx, intestine, body-wall muscle and gonadal tissue. Required for larval development. Isoform c operates in the assembly of the flexible hemicentin-containing tracks found joining the pharynx and body-wall-muscle basement membranes.
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 Research Articles on fbl-1    1. A series of deletion constructs shows that EGF repeats 4 and 5 are required for the hemicentin-dependent assembly and function of fibulin-1D in native locations.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with fbl-1 recombinant protein
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >1 publications with fbl-1 and Fibrosis
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