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FBLN2 recombinant protein :: Fibulin 2 (FBLN2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2011606 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $260 +1 FREE 8GB USB
0.1 mg  /  $400 +1 FREE 8GB USB
0.2 mg  /  $495 +1 FREE 8GB USB
0.5 mg  /  $955 +1 FREE 8GB USB
1 mg  /  $1,415 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fibulin 2 (FBLN2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Fibulin 2 (FBLN2)

 Product Gene Name   

FBLN2 recombinant protein

[Similar Products]
 Matching Pairs    Antibody: Fibulin 2 (FBLN2) (MBS2005266)
Antigen: Fibulin 2 (FBLN2) (MBS2011606)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2011606 Technical Datasheet    Technical Datasheet PDF
 Chromosome Location    Chromosome: 3; NC_000003.11 (13573824..13679922). Location: 3p25.1
 OMIM    135821
 3D Structure    ModBase 3D Structure for P98095
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 Host    E. coli
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 Purity/Purification    >95%
 Concentration    Original Concentration: 200 ug/mL (lot specific)
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 Organism Specie    Homo sapiens (Human)
 Source    Prokaryotic expression
 Residues    Ile858~Ser1069
 Tags    N-terminal His Tag
 Subcellular Location    Secreted, Extracellular matrix
 Traits    Freeze-dried powder
 Buffer    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
 Predicted isoelectric point    5.6
 Predicted Molecular Mass    24.3kDa
 Accurate Molecular Mass    27kDa as determined by SDS-PAGE reducing conditions
 Usage    Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8C for one month.
Aliquot and store at -80C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of FBLN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for FBLN2 recombinant protein   

Positive Control; Immunogen; SDS-PAGE; WB.

(May be suitable for use in other assays to be determined by the end user.)

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 Sequence of FBLN2 recombinant protein    FBLN2 recombinant protein Sequence image
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 SDS-PAGE of FBLN2 recombinant protein    FBLN2 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for FBLN2. It may not necessarily be applicable to this product.
 NCBI GI #    51873053
 NCBI GeneID    2199
 NCBI Accession #    NP_001004019.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001004019.1 [Other Products]
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 UniProt Primary Accession #    P98095 [Other Products]
 UniProt Secondary Accession #    Q8IUI0; Q8IUI1; B7Z9C5 [Other Products]
 UniProt Related Accession #    P98095 [Other Products]
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 NCBI Official Full Name    fibulin-2 isoform a
 NCBI Official Synonym Full Names    fibulin 2
 NCBI Official Symbol    FBLN2 [Similar Products]
 NCBI Protein Information    fibulin-2; FIBL-2
 UniProt Protein Name    Fibulin-2
 Protein Family    Fibulin
 UniProt Gene Name    FBLN2 [Similar Products]
 UniProt Synonym Gene Names    FIBL-2 [Similar Products]
 UniProt Entry Name    FBLN2_HUMAN
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 NCBI Summary for FBLN2    This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FBLN2    FBLN2: Its binding to fibronectin and some other ligands is calcium dependent. Belongs to the fibulin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular region; vesicle

Molecular Function: extracellular matrix binding; extracellular matrix structural constituent; calcium ion binding

Biological Process: extracellular matrix organization and biogenesis
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 Research Articles on FBLN2    1. Study identified and validated a novel bona fide target of miR-1, Fibullin-2 (Fbln2), a secreted protein implicated in extracellular matrix remodeling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FBLN2 recombinant proteinPathways associated with FBLN2 recombinant protein
 Reference Product  PubMed Publications
 FBN1 recombinant protein  >2 publications with FBLN2 and FBN1
 Products by Pathway  Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Molecules Associated With Elastic Fibres Pathway antibodies  Molecules Associated With Elastic Fibres Pathway Diagram
Diseases associated with FBLN2 recombinant proteinOrgans/Tissues associated with FBLN2 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7 publications with FBLN2 and Neoplasms
 Cardiovascular Diseases Antibodies  >6 publications with FBLN2 and Cardiovascular Diseases
 Carcinoma Antibodies  >5 publications with FBLN2 and Carcinoma
 Lung Neoplasms Antibodies  >4 publications with FBLN2 and Lung Neoplasms
 Fibrosis Antibodies  >3 publications with FBLN2 and Fibrosis
 Adenocarcinoma Antibodies  >2 publications with FBLN2 and Adenocarcinoma
 Hypertrophy Antibodies  >2 publications with FBLN2 and Hypertrophy
 Hypertension Antibodies  >2 publications with FBLN2 and Hypertension
 Colorectal Neoplasms Antibodies  >2 publications with FBLN2 and Colorectal Neoplasms
 Disease Models, Animal Antibodies  >1 publications with FBLN2 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >6 publications with FBLN2 and Heart
 Vascular Antibodies  >5 publications with FBLN2 and Vascular
 Lung Antibodies  >4 publications with FBLN2 and Lung
 Muscle Antibodies  >3 publications with FBLN2 and Muscle
 Embryonic Tissue Antibodies  >2 publications with FBLN2 and Embryonic Tissue
 Ovary Antibodies  >2 publications with FBLN2 and Ovary
 Skin Antibodies  >1 publications with FBLN2 and Skin
 Prostate Antibodies  >1 publications with FBLN2 and Prostate
 Connective Tissue Antibodies  >1 publications with FBLN2 and Connective Tissue
 Bone Antibodies  >1 publications with FBLN2 and Bone
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