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FOXL2 recombinant protein :: Forkhead box protein L2 (FOXL2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS954234 FOXL2 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $785 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,030 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,055 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,160 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,210 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,275 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,305 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,365 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,650 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,880 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,935 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,075 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,495 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Forkhead box protein L2 (FOXL2), Recombinant Protein

 Also Known As   

Recombinant Human Forkhead box protein L2 (FOXL2)

 Product Gene Name   

FOXL2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-376aa, Full length protein
 Sequence    MMASYPEPED AAGALLAPET GRTVKEPEGP PPSPGKGGGG GGGTAPEKPD PAQKPPYSYV ALIAMAIRES AEKRLTLSGI YQYIIAKFPF YEKNKKGWQN SIRHNLSLNE CFIKVPREGG GERKGNYWTL DPACEDMFEK GNYRRRRRMK RPFRPPPAHF QPGKGLFGAG GAAGGCGVAG AGADGYGYLA PPKYLQSGFL NNSWPLPQPP SPMPYASCQM AAAAAAAAAA AAAAGPGSPG AAAVVKGLAG PAASYGPYTR VQSMALPPGV VNSYNGLGGP PAAPPPPPHP HPHPHAHHLH AAAAPPPAPP HHGAAAPPPG QLSPASPATA APPAPAPTSA PGLQFACARQ PELAMMHCSY WDHDSKTGAL HSRLDL
 OMIM    110100
 3D Structure    ModBase 3D Structure for P58012
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of FOXL2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for FOXL2 recombinant protein

   This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3.
NCBI/Uniprot data below describe general gene information for FOXL2. It may not necessarily be applicable to this product.
 NCBI GI #    12751477
 NCBI GeneID    668
 NCBI Accession #    NP_075555.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_023067.3 [Other Products]
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 UniProt Primary Accession #    P58012 [Other Products]
 UniProt Secondary Accession #    Q4ZGJ3 [Other Products]
 UniProt Related Accession #    P58012 [Other Products]
 Molecular Weight    38,772 Da
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 NCBI Official Full Name    forkhead box protein L2
 NCBI Official Synonym Full Names    forkhead box L2
 NCBI Official Symbol    FOXL2 [Similar Products]
 NCBI Official Synonym Symbols   
BPES; PFRK; POF3; BPES1; PINTO
[Similar Products]
 NCBI Protein Information    forkhead box protein L2
 UniProt Protein Name    Forkhead box protein L2
 Protein Family    Forkhead box protein
 UniProt Gene Name    FOXL2 [Similar Products]
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 NCBI Summary for FOXL2    This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Expansion of a polyalanine repeat region and other mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. [provided by RefSeq, Jul 2016]
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 UniProt Comments for FOXL2    Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (). Is a regulator of CYP19 expression (). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
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 Research Articles on FOXL2    1. Our results suggest that, in contrast to FOXL2 mutations in adult granulosa cell tumours (A-GCTs), DICER1 mutations in Sertoli-Leydig cell tumours (SLCTs) might be more useful for prognosis than for diagnosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FOXL2 recombinant proteinDiseases associated with FOXL2 recombinant protein
 Reference Product  PubMed Publications
 CYP19A1 recombinant protein  >65 publications with FOXL2 and CYP19A1
 SOX9 recombinant protein  >62 publications with FOXL2 and SOX9
 RSPO1 recombinant protein  >20 publications with FOXL2 and RSPO1
 NR5A1 recombinant protein  >16 publications with FOXL2 and NR5A1
 SMAD3 recombinant protein  >12 publications with FOXL2 and SMAD3
 SIRT1 recombinant protein  >2 publications with FOXL2 and SIRT1
 GNRHR recombinant protein  >2 publications with FOXL2 and GNRHR
 MRPS22 recombinant protein  >1 publications with FOXL2 and MRPS22
 LHX4 recombinant protein  >1 publications with FOXL2 and LHX4
 DDX20 recombinant protein  >1 publications with FOXL2 and DDX20
 Disease Name  Pubmed Publications
 Urogenital Abnormalities Antibodies  >35 publications with FOXL2 and Urogenital Abnormalities
 Premature Ovarian Failure 3 Antibodies  >26 publications with FOXL2 and Premature Ovarian Failure 3
 Infertility, Male Antibodies  >7 publications with FOXL2 and Infertility, Male
 Blepharophimosis syndrome type 1 Antibodies  >6 publications with FOXL2 and Blepharophimosis syndrome type 1
 Blepharophimosis, Ptosis, and Epicanthus Inversus Antibodies  >6 publications with FOXL2 and Blepharophimosis, Ptosis, and Epicanthus Inversus
 Disease Models, Animal Antibodies  >5 publications with FOXL2 and Disease Models, Animal
 Microcephaly Antibodies  >3 publications with FOXL2 and Microcephaly
 Colorectal Neoplasms Antibodies  >3 publications with FOXL2 and Colorectal Neoplasms
 Pituitary Neoplasms Antibodies  >3 publications with FOXL2 and Pituitary Neoplasms
 Adenocarcinoma Antibodies  >2 publications with FOXL2 and Adenocarcinoma
Organs/Tissues associated with FOXL2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >174 publications with FOXL2 and Ovary
 Brain Antibodies  >28 publications with FOXL2 and Brain
 Heart Antibodies  >5 publications with FOXL2 and Heart
 Uterus Antibodies  >3 publications with FOXL2 and Uterus
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