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FOXO4 recombinant protein :: Forkhead box protein O4 (FOXO4) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS957757 FOXO4 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $925 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,130 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,240 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,355 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,370 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,380 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,435 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,535 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,950 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,055 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,085 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,335 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,705 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Forkhead box protein O4 (FOXO4), Recombinant Protein

 Also Known As   

Recombinant Human Forkhead box protein O4 (FOXO4)

 Product Gene Name   

FOXO4 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-505aa, Full length protein
 Sequence    MDPGNENSAT EAAAIIDLDP DFEPQSRPRS CTWPLPRPEI ANQPSEPPEV EPDLGEKVHT EGRSEPILLP SRLPEPAGGP QPGILGAVTG PRKGGSRRNA WGNQSYAELI SQAIESAPEK RLTLAQIYEW MVRTVPYFKD KGDSNSSAGW KNSIRHNLSL HSKFIKVHNE ATGKSSWWML NPEGGKSGKA PRRRAASMDS SSKLLRGRSK APKKKPSVLP APPEGATPTS PVGHFAKWSG SPCSRNREEA DMWTTFRPRS SSNASSVSTR LSPLRPESEV LAEEIPASVS SYAGGVPPTL NEGLELLDGL NLTSSHSLLS RSGLSGFSLQ HPGVTGPLHT YSSSLFSPAE GPLSAGEGCF SSSQALEALL TSDTPPPPAD VLMTQVDPIL SQAPTLLLLG GLPSSSKLAT GVGLCPKPLE APGPSSLVPT LSMIAPPPVM ASAPIPKALG TPVLTPPTEA ASQDRMPQDL DLDMYMENLE CDMDNIISDL MDEGEGLDFN FEPDP
 OMIM    300033
 3D Structure    ModBase 3D Structure for P98177
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of FOXO4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for FOXO4 recombinant protein

   This gene encodes a member of the O class of winged helix
forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for FOXO4. It may not necessarily be applicable to this product.
 NCBI GI #    283436083
 NCBI GeneID    4303
 NCBI Accession #    NP_001164402.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001170931.1 [Other Products]
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 UniProt Primary Accession #    P98177 [Other Products]
 UniProt Secondary Accession #    O43821; Q13720; Q3KPF1; Q8TDK9; B7WPJ7 [Other Products]
 UniProt Related Accession #    P98177 [Other Products]
 Molecular Weight    47,941 Da
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 NCBI Official Full Name    forkhead box protein O4 isoform 2
 NCBI Official Synonym Full Names    forkhead box O4
 NCBI Official Symbol    FOXO4 [Similar Products]
 NCBI Official Synonym Symbols   
AFX; AFX1; MLLT7
[Similar Products]
 NCBI Protein Information    forkhead box protein O4
 UniProt Protein Name    Forkhead box protein O4
 UniProt Synonym Protein Names   
Fork head domain transcription factor AFX1
 Protein Family    Forkhead box protein
 UniProt Gene Name    FOXO4 [Similar Products]
 UniProt Synonym Gene Names    AFX; AFX1; MLLT7 [Similar Products]
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 NCBI Summary for FOXO4    This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
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 UniProt Comments for FOXO4    Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
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 Research Articles on FOXO4    1. Results show that a small subset of lymphoma cells surviving treatment with doxorubicin or phenylbutyrate showed stem cell-like properties and resistance to chemotherapeuty. The overexpression of FOXO4 was found in these surviving cells, and DLBCL patients with FOXO4-positive tumor cells had poor prognosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FOXO4 recombinant proteinPathways associated with FOXO4 recombinant protein
 Reference Product  PubMed Publications
 AKT1 recombinant protein  >20 publications with FOXO4 and AKT1
 CCND1 recombinant protein  >9 publications with FOXO4 and CCND1
 CTNNB1 recombinant protein  >7 publications with FOXO4 and CTNNB1
 CREBBP recombinant protein  >3 publications with FOXO4 and CREBBP
 AKT2 recombinant protein  >2 publications with FOXO4 and AKT2
 CDKN1A recombinant protein  >2 publications with FOXO4 and CDKN1A
 SMAD4 recombinant protein  >1 publications with FOXO4 and SMAD4
 FOXG1 recombinant protein  >1 publications with FOXO4 and FOXG1
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 AKT Phosphorylates Targets In The Nucleus Pathway antibodies  AKT Phosphorylates Targets In The Nucleus Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Class I PI3K Signaling Events Mediated By Akt Pathway antibodies  Class I PI3K Signaling Events Mediated By Akt Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
Diseases associated with FOXO4 recombinant proteinOrgans/Tissues associated with FOXO4 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >41 publications with FOXO4 and Neoplasms
 Cardiovascular Diseases Antibodies  >11 publications with FOXO4 and Cardiovascular Diseases
 Necrosis Antibodies  >10 publications with FOXO4 and Necrosis
 Inflammation Antibodies  >9 publications with FOXO4 and Inflammation
 Ischemia Antibodies  >8 publications with FOXO4 and Ischemia
 Disease Models, Animal Antibodies  >7 publications with FOXO4 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >4 publications with FOXO4 and Neoplasm Metastasis
 Atherosclerosis Antibodies  >4 publications with FOXO4 and Atherosclerosis
 Hyperglycemia Antibodies  >4 publications with FOXO4 and Hyperglycemia
 Neoplasm Invasiveness Antibodies  >3 publications with FOXO4 and Neoplasm Invasiveness
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >36 publications with FOXO4 and Blood
 Liver Antibodies  >18 publications with FOXO4 and Liver
 Brain Antibodies  >13 publications with FOXO4 and Brain
 Embryonic Tissue Antibodies  >9 publications with FOXO4 and Embryonic Tissue
 Bone Antibodies  >7 publications with FOXO4 and Bone
 Kidney Antibodies  >6 publications with FOXO4 and Kidney
 Ovary Antibodies  >6 publications with FOXO4 and Ovary
 Prostate Antibodies  >4 publications with FOXO4 and Prostate
 Intestine Antibodies  >4 publications with FOXO4 and Intestine
 Eye Antibodies  >4 publications with FOXO4 and Eye
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