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Fxn recombinant protein :: Frataxin, mitochondrial (Fxn) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7054874
SDS-PAGE
Unit / Price
0.05 mg (E-Coli)  /  $565 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $755 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $835 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,170 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Frataxin, mitochondrial (Fxn), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Frataxin, mitochondrial (Fxn)

 Product Gene Name   

Fxn recombinant protein

[Similar Products]
 Product Synonym Gene Name    Fxn [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    41-208aa; Full Length of Mature Protein
 Sequence    LHVTANADAI RHSHLNLHYL GQILNIKKQS VCVVHLRNSG TLGNPSSLDE TAYERLAEET LDALAEFFED LADKPYTLKD YDVSFGDGVL TIKLGGDLGT YVINKQTPLL YLWFSGPCSG PKRYDWTGKN WVYSHDGVSL HELLARELTE ALNTKLDLSS LAYSGKGT
 3D Structure    ModBase 3D Structure for D3ZYW7
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Fxn recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Fxn recombinant protein

   Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1
 Product Categories/Family for Fxn recombinant protein    Tags & Cell Markers
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 SDS-PAGE of Fxn recombinant protein    Fxn recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Fxn. It may not necessarily be applicable to this product.
 NCBI GI #    308191430
 NCBI GeneID    499335
 NCBI Accession #    D3ZYW7.1 [Other Products]
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 UniProt Primary Accession #    D3ZYW7 [Other Products]
 UniProt Related Accession #    D3ZYW7 [Other Products]
 Molecular Weight    18.6kDa [Similar Products]
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 NCBI Official Full Name    Frataxin, mitochondrial
 NCBI Official Synonym Full Names    frataxin
 NCBI Official Symbol    Fxn [Similar Products]
 NCBI Official Synonym Symbols   
RGD1565754
[Similar Products]
 NCBI Protein Information    frataxin, mitochondrial
 UniProt Protein Name    Frataxin, mitochondrial
 UniProt Gene Name    Fxn [Similar Products]
 UniProt Synonym Gene Names    Fxn [Similar Products]
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 UniProt Comments for Fxn    Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 ().
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Product References and Citations for Fxn recombinant protein

   "Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity." Bulteau A.L., O'Neill H.A., Kennedy M.C., Ikeda-Saito M., Isaya G., Szweda L.I. Science 305:242-245(2004)
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 Research Articles on Fxn    1. frataxin deficiency in neonatal rat ventricular myocytes leads to mitochondrial dysfunction and oxidative stress, which would affect lipid metabolism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Fxn recombinant proteinPathways associated with Fxn recombinant protein
 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with Fxn and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with Fxn recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >10 publications with Fxn and Heart
 Brain Antibodies  >8 publications with Fxn and Brain
 Kidney Antibodies  >2 publications with Fxn and Kidney
 Embryonic Tissue Antibodies  >2 publications with Fxn and Embryonic Tissue
 Pancreas Antibodies  >1 publications with Fxn and Pancreas
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