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FFAR2 recombinant protein :: Free fatty acid receptor 2 (FFAR2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1043673 FFAR2 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $815 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $815 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,040 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,040 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,100 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,100 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,560 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,560 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,595 +1 FREE 8GB USB
1 mg (Baculovirus)  /  $2,180 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Free fatty acid receptor 2 (FFAR2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Free fatty acid receptor 2 (FFAR2)

 Product Synonym Names    Recombinant Free fatty acid receptor 2 (FFAR2); Free fatty acid receptor 2; G-protein coupled receptor 43
 Product Gene Name   

FFAR2 recombinant protein

[Similar Products]
 Product Synonym Gene Name    FFAR2; GPR43 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1043673 COA    COA PDF
 Sequence Positions    277-330. Fragment at the C-terminal, provide the last complete extracellular domain.
 Sequence    SSVVRRAFGR GLQVLRNQGS SLLGRRGKDT AEGTNEDRGV GQGEGMPSSD FTTE
 Chromosome Location    Chromosome: 19; NC_000019.9 (35940617..35942669). Location: 19q13.1
 OMIM    603823
 3D Structure    ModBase 3D Structure for O15552
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of FFAR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for FFAR2. It may not necessarily be applicable to this product.
 NCBI GI #    4885333
 NCBI GeneID    2867
 NCBI Accession #    NP_005297.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005306.2 [Other Products]
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 UniProt Primary Accession #    O15552 [Other Products]
 UniProt Secondary Accession #    Q4VAZ3; Q4VAZ5; Q4VBL5; B0M0J9 [Other Products]
 UniProt Related Accession #    O15552 [Other Products]
 Molecular Weight    37,144 Da [Similar Products]
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 NCBI Official Full Name    free fatty acid receptor 2
 NCBI Official Synonym Full Names    free fatty acid receptor 2
 NCBI Official Symbol    FFAR2 [Similar Products]
 NCBI Official Synonym Symbols   
FFA2R; GPR43
[Similar Products]
 NCBI Protein Information    free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; free fatty acid activated receptor 2
 UniProt Protein Name    Free fatty acid receptor 2
 UniProt Synonym Protein Names   
G-protein coupled receptor 43
 Protein Family    Free fatty acid receptor
 UniProt Gene Name    FFAR2 [Similar Products]
 UniProt Synonym Gene Names    GPR43 [Similar Products]
 UniProt Entry Name    FFAR2_HUMAN
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 NCBI Summary for FFAR2    This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009]
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 UniProt Comments for FFAR2    FFAR2: Receptor for short chain fatty acids through a G(i)- protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: cell projection; integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; lipid binding

Biological Process: fat cell differentiation; G-protein coupled receptor protein signaling pathway; sequestering of lipid; mucosal immune response; regulation of acute inflammatory response; cell surface pattern recognition receptor signaling pathway; positive regulation of cytokine production during immune response; positive regulation of acute inflammatory response to non-antigenic stimulus; glucose homeostasis; leukocyte chemotaxis during inflammatory response; positive regulation of chemokine production
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 Research Articles on FFAR2    1. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with FFAR2 recombinant proteinDiseases associated with FFAR2 recombinant protein
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Free Fatty Acid Receptors Pathway antibodies  Free Fatty Acid Receptors Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >2 publications with FFAR2 and Insulin Resistance
 Colitis Antibodies  >2 publications with FFAR2 and Colitis
 Inflammation Antibodies  >2 publications with FFAR2 and Inflammation
 Obesity Antibodies  >1 publications with FFAR2 and Obesity
 Asthma Antibodies  >1 publications with FFAR2 and Asthma
 Dyslipidemias Antibodies  >1 publications with FFAR2 and Dyslipidemias
 Colitis, Ulcerative Antibodies  >1 publications with FFAR2 and Colitis, Ulcerative
 Hypoglycemia Antibodies  >1 publications with FFAR2 and Hypoglycemia
 Fatty Liver Antibodies  >1 publications with FFAR2 and Fatty Liver
Organs/Tissues associated with FFAR2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >1 publications with FFAR2 and Pancreas
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