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G-CSF recombinant protein

Scan QR to view Datasheet Catalog #    MBS232342 G-CSF recombinant protein
Unit / Price
0.01 mg  /  $430 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

G-CSF, Recombinant Protein

 Also Known As   

RECOMBINANT MOUSE G-CSF

 Product Gene Name   

G-CSF recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P09920
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 Purity/Purification    >98% by SDS PAGE and HPLC
 Form/Format    Purified recombinant protein - lyophilised
 Concentration    Approximate Protein Concentration: 1.0 mg/ml (lot specific)
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 Reconstitution    Reconstitute with 10 ul distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution.
Preparation
 Buffer Solution    5mM Sodium Citrate pH4.0
 Target Species    Mouse
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 Preparation and Storage    Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 3 months from date of reconstitution.
 Other Notes    Small volumes of G-CSF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for G-CSF recombinant protein

   Granulocyte colony stimulating factor (G-CSF) stimulates the proliferation and differentiation of granulocyte progenitors in the bone marrow.
 Applications Tested/Suitable for G-CSF recombinant protein   

Functional Assays (FN)

 Application Notes for G-CSF recombinant protein    Functional Assays: Minimum Dilution: 0.1ng/ml; Maximum Dilution: 1.0ng/ml
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NCBI/Uniprot data below describe general gene information for G-CSF. It may not necessarily be applicable to this product.
 NCBI GI #    6753536
 NCBI GeneID    12985
 NCBI Accession #    NP_034101.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_009971.1 [Other Products]
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 UniProt Primary Accession #    P09920 [Other Products]
 UniProt Related Accession #    P09920 [Other Products]
 Molecular Weight    Protein Molecular Weight: 19.0kD (179 amino acid sequence)
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 NCBI Official Full Name    granulocyte colony-stimulating factor
 NCBI Official Synonym Full Names    colony stimulating factor 3 (granulocyte)
 NCBI Official Symbol    Csf3 [Similar Products]
 NCBI Official Synonym Symbols   
Csfg; G-CSF; MGI-IG
[Similar Products]
 NCBI Protein Information    granulocyte colony-stimulating factor
 UniProt Protein Name    Granulocyte colony-stimulating factor
 UniProt Gene Name    Csf3 [Similar Products]
 UniProt Synonym Gene Names    Csfg; G-CSF [Similar Products]
 UniProt Entry Name    CSF3_MOUSE
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 UniProt Comments for G-CSF    G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Cell cycle regulation; Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: enzyme binding; growth factor activity; cytokine activity

Biological Process: positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of myeloid cell differentiation; positive regulation of actin filament polymerization; positive regulation of protein binding; granulocyte differentiation; positive regulation of cell proliferation; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; immune response; positive regulation of peptidyl-serine phosphorylation
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 Research Articles on G-CSF    1. Cultured mouse enteric nervous system -neurospheres show increased expansion with increased G-CSF concentrations, in contrast to central nervous system - derived spheres.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with G-CSF recombinant proteinDiseases associated with G-CSF recombinant protein
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Disease Susceptibility Antibodies  >6 publications with G-CSF and Disease Susceptibility
 Nervous System Diseases Antibodies  >5 publications with G-CSF and Nervous System Diseases
 Breast Neoplasms Antibodies  >3 publications with G-CSF and Breast Neoplasms
 Neutropenia Antibodies  >3 publications with G-CSF and Neutropenia
 Leukopenia Antibodies  >2 publications with G-CSF and Leukopenia
 Anemia Antibodies  >2 publications with G-CSF and Anemia
 Neoplasm Metastasis Antibodies  >2 publications with G-CSF and Neoplasm Metastasis
 Leukemia, Myeloid, Acute Antibodies  >2 publications with G-CSF and Leukemia, Myeloid, Acute
 Peripheral Nervous System Diseases Antibodies  >1 publications with G-CSF and Peripheral Nervous System Diseases
 Pulmonary Fibrosis Antibodies  >1 publications with G-CSF and Pulmonary Fibrosis
Organs/Tissues associated with G-CSF recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >5 publications with G-CSF and Lung
 Mammary Gland Antibodies  >3 publications with G-CSF and Mammary Gland
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