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Add To Compare List CCND2 recombinant protein :: G1/S-specific cyclin-D2 (CCND2) Recombinant Protein Catalog # MBS955606 Unit / Price 0.02 mg (E-Coli) / $820 +1 FREE 8GB USB 0.02 mg (Yeast) / $965 +1 FREE 8GB USB 0.1 mg (E-Coli) / $980 +1 FREE 8GB USB 0.1 mg (Yeast) / $1,130 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,175 +1 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,445 +1 FREE 8GB USB 0.1 mg (Baculovirus) / $1,685 +2 FREE 8GB USB 1 mg (E-Coli) / $1,745 +2 FREE 8GB USB 1 mg (Yeast) / $2,165 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,270 +2 FREE 8GB USB 1 mg (Baculovirus) / $3,295 +4 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $5,960 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name G1/S-specific cyclin-D2 (CCND2), Recombinant Protein Full Product Name Recombinant Chicken G1/S-specific cyclin-D2 (CCND2) Product Gene Name CCND2 recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 1-291, Full length protein Sequence MELLCCEVDP MRRALPDPNL LYDDRVLHNL LTIEERYLPQ CSYFKCVQKD IQPFMRRMVA TWMLEVCEEQ KCEEEVFPLA MNYLDRFLAV VPTRKCHLQL LGAVCMFLAS KLKETIPLTA EKLCIYTDNS IKPQELLEWE LVVLGKLKWN LAAVTPHDFI EHILRKLPLP KDKLVLIRKH AQTFIALCAT DFNFAMYPPS MIATGSVGAA ICGLQLDDGD RSLSGDSLTD FLAKITSTDV DCLKACQEQI ESVLVSNLRQ VRQQQQQSNP SKTIEELDQA STPTDVRDIN L 3D Structure ModBase 3D Structure for P49706 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Chicken Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of CCND2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for CCND2 recombinant protein This protein belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. NCBI/Uniprot data below describe general gene information for CCND2. It may not necessarily be applicable to this product. NCBI GI # 45383698 NCBI GeneID 374047 NCBI Accession # NP_989544.1 [Other Products] NCBI GenBank Nucleotide # NM_204213.1 [Other Products] UniProt Primary Accession # P49706 [Other Products] UniProt Related Accession # P49706[Other Products] Molecular Weight 33,164 Da TOP NCBI Official Full Name G1/S-specific cyclin-D2 NCBI Official Synonym Full Names cyclin D2 NCBI Official Symbol CCND2 [Similar Products] NCBI Protein Information G1/S-specific cyclin-D2 UniProt Protein Name G1/S-specific cyclin-D2 Protein Family G1/S-specific cyclin UniProt Gene Name CCND2 [Similar Products] TOP TOP UniProt Comments for CCND2 Essential for the control of the cell cycle at the G1/S (start) transition. Research Articles on CCND2 1. FGF signaling maintains cyclin D2 in the immature caudal neural epithelium, while Shh activates cyclin D1 in the neural groove. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. 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TOP Products associated with CCND2 recombinant protein Reference Product PubMed Publications CDKN1B recombinant protein >90 publications with CCND2 and CDKN1B CDK6 recombinant protein >56 publications with CCND2 and CDK6 PCNA recombinant protein >24 publications with CCND2 and PCNA CDKN2C recombinant protein >17 publications with CCND2 and CDKN2C RB1 recombinant protein >16 publications with CCND2 and RB1 RBL2 recombinant protein >4 publications with CCND2 and RBL2 RBL1 recombinant protein >1 publications with CCND2 and RBL1 Pathways associated with CCND2 recombinant protein Products by Pathway Pathway Diagram B Cell Receptor Signaling Pathway antibodies B Cell Receptor Signaling Pathway Diagram Cell Cycle Pathway antibodies Cell Cycle Pathway Diagram Cell Cycle Pathway antibodies Cell Cycle Pathway Diagram Cell Cycle Pathway antibodies Cell Cycle Pathway Diagram Cell Cycle - G1/S Transition Pathway antibodies Cell Cycle - G1/S Transition Pathway Diagram Cell Cycle - G1/S Transition Pathway antibodies Cell Cycle - G1/S Transition Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram FoxO Signaling Pathway antibodies FoxO Signaling Pathway Diagram G1 To S Cell Cycle Control Pathway antibodies G1 To S Cell Cycle Control Pathway Diagram Diseases associated with CCND2 recombinant protein Disease Name Pubmed Publications Breast Neoplasms Antibodies >51 publications with CCND2 and Breast Neoplasms Cardiovascular Diseases Antibodies >49 publications with CCND2 and Cardiovascular Diseases Cell Transformation, Neoplastic Antibodies >49 publications with CCND2 and Cell Transformation, Neoplastic Neoplasms, Experimental Antibodies >36 publications with CCND2 and Neoplasms, Experimental Nervous System Diseases Antibodies >30 publications with CCND2 and Nervous System Diseases Neoplasm Invasiveness Antibodies >24 publications with CCND2 and Neoplasm Invasiveness Lung Neoplasms Antibodies >21 publications with CCND2 and Lung Neoplasms Neoplasm Metastasis Antibodies >20 publications with CCND2 and Neoplasm Metastasis Prostatic Neoplasms Antibodies >20 publications with CCND2 and Prostatic Neoplasms Heart Diseases Antibodies >18 publications with CCND2 and Heart Diseases Organs/Tissues associated with CCND2 recombinant protein Organ/Tissue Name Pubmed Publications Blood Antibodies >176 publications with CCND2 and Blood Brain Antibodies >68 publications with CCND2 and Brain Gonad Antibodies >65 publications with CCND2 and Gonad Ovary Antibodies >57 publications with CCND2 and Ovary Pancreas Antibodies >31 publications with CCND2 and Pancreas Embryonic Tissue Antibodies >31 publications with CCND2 and Embryonic Tissue Spleen Antibodies >16 publications with CCND2 and Spleen Head Antibodies >13 publications with CCND2 and Head Limb Antibodies >3 publications with CCND2 and Limb TOP © 2006-24 MyBioSource.com. 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