NP_002077
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27 kDa (237 aa), confirmed by MALDI-TOF.
NCBI Official Full Name
growth factor receptor-bound protein 2 isoform 1
NCBI Official Synonym Full Names
growth factor receptor bound protein 2
NCBI Official Synonym Symbols
ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2 [Similar Products]
NCBI Protein Information
growth factor receptor-bound protein 2
UniProt Protein Name
Growth factor receptor-bound protein 2
UniProt Synonym Protein Names
Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2
UniProt Synonym Gene Names
NCBI Summary for GRB2
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for GRB2
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Product References and Citations for GRB2 recombinant protein
Rudd CE., et al. (2009) Immunol Rev. 229 (1):12-26.; Weisswange I., et al. (2009) Nature. 458 (7234):87-91.;
Research Articles on GRB2
Precautions
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Disclaimer
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Products associated with GRB2 recombinant protein
Pathways associated with GRB2 recombinant protein
Diseases associated with GRB2 recombinant protein
Organs/Tissues associated with GRB2 recombinant protein
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