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Cxcl1 recombinant protein :: GRO/KC, Rat Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS651024 Cxcl1 recombinant protein
Unit / Price
0.005 mg  /  $315 +1 FREE 8GB USB
0.025 mg  /  $455 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GRO/KC, Rat (Cxcl1), Recombinant Protein

★Popular Item★
 Also Known As   

GRO/KC, Recombinant, Rat (Cxcl1, Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, alpha), Cinc1, CINC-1, C-X-C Motif Chemokine 1, Cytokine-induced Neutrophil Chemoattractant 1, Gro1, Growth-regulated alpha Protein, Platelet-derived

 Product Synonym Names    GRO/KC, Recombinant, Rat (Cxcl1, Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, alpha), Cinc1, CINC-1, C-X-C Motif Chemokine 1, Cytokine-induced Neutrophil Chemoattractant 1, Gro1, Growth-regulated alpha Protein, Platelet-derived
 Product Gene Name   

Cxcl1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 14; NC_005113.3 (18653032..18654811, complement). Location: 14p22
 3D Structure    ModBase 3D Structure for P14095
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 Host    E Coli
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 Purity/Purification    Molecular Biology Grade
98% by SDS-PAGE and HPLC
 Form/Format    Supplied as a lyophilized powder. No additives. Reconstitute in sterile dH2O to 0.1-1mg/ml. This solution can then be diluted into other aqueous buffers.
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 Biological Activity    Determined by ability to chemoattract total rat neutrophils at a concentration range of 10-100ng/ml.
 Endotoxin Level    0.1ng/ug
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute by adding sterile water, aliquot and store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of Cxcl1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Cxcl1 recombinant protein

   All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8kD protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
 Product Categories/Family for Cxcl1 recombinant protein    Growth Factors, Cytokines; Growth Factors-GRO
NCBI/Uniprot data below describe general gene information for Cxcl1. It may not necessarily be applicable to this product.
 NCBI GI #    13540652
 NCBI GeneID    81503
 NCBI Accession #    NP_110472.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030845.1 [Other Products]
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 UniProt Primary Accession #    P14095 [Other Products]
 UniProt Related Accession #    P14095 [Other Products]
 Molecular Weight    7.8kD [Similar Products]
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 NCBI Official Full Name    growth-regulated alpha protein
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) ligand 1
 NCBI Official Symbol    Cxcl1 [Similar Products]
 NCBI Official Synonym Symbols   
Gro1; CINC-1
[Similar Products]
 NCBI Protein Information    growth-regulated alpha protein; C-X-C motif chemokine 1; cytokine-induced neutrophil chemoattractant 1; platelet-derived growth factor-inducible protein KC; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
 UniProt Protein Name    Growth-regulated alpha protein
 UniProt Synonym Protein Names   
C-X-C motif chemokine 1; Cytokine-induced neutrophil chemoattractant 1; CINC-1; Platelet-derived growth factor-inducible protein KC
 Protein Family    Growth-regulated alpha protein
 UniProt Gene Name    Cxcl1 [Similar Products]
 UniProt Synonym Gene Names    Cinc1; Gro; Scyb1; CINC-1 [Similar Products]
 UniProt Entry Name    GROA_RAT
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 NCBI Summary for Cxcl1    acts as a neutrophil chemoattractant; may play a role in acute phase inflammatory response [RGD, Feb 2006]
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 UniProt Comments for Cxcl1    Function: Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation.

Subunit structure: Monomer and homodimer.

Subcellular location: Secreted.

Tissue specificity: At least expressed in the lung and trachea.

Induction: By lipopolysaccharides (LPS) and inflammation.

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
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 Research Articles on Cxcl1    1. Function of the transient receptor potential vanilloid (TRPV)1 channel is enhanced by dorsal root ganglia inflammation. The effects (decreased tachyphylaxis) are mimicked by incubation with GRO/KC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Cxcl1 recombinant proteinPathways associated with Cxcl1 recombinant protein
 Reference Product  PubMed Publications
 Cxcl2 recombinant protein  >486 publications with Cxcl1 and Cxcl2
 Ccl2 recombinant protein  >461 publications with Cxcl1 and Ccl2
 Il8rb recombinant protein  >202 publications with Cxcl1 and Il8rb
 Cxcl3 recombinant protein  >83 publications with Cxcl1 and Cxcl3
 Cxcl6 recombinant protein  >65 publications with Cxcl1 and Cxcl6
 Cxcr4 recombinant protein  >46 publications with Cxcl1 and Cxcr4
 Il6 recombinant protein  >41 publications with Cxcl1 and Il6
 Ccr2 recombinant protein  >36 publications with Cxcl1 and Ccr2
 Cxcr3 recombinant protein  >29 publications with Cxcl1 and Cxcr3
 Ppbp recombinant protein  >21 publications with Cxcl1 and Ppbp
 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
Diseases associated with Cxcl1 recombinant proteinOrgans/Tissues associated with Cxcl1 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >958 publications with Cxcl1 and Inflammation
 Necrosis Antibodies  >486 publications with Cxcl1 and Necrosis
 Disease Models, Animal Antibodies  >352 publications with Cxcl1 and Disease Models, Animal
 Lung Diseases Antibodies  >286 publications with Cxcl1 and Lung Diseases
 Neoplasms Antibodies  >282 publications with Cxcl1 and Neoplasms
 Cardiovascular Diseases Antibodies  >163 publications with Cxcl1 and Cardiovascular Diseases
 Lung Injury Antibodies  >156 publications with Cxcl1 and Lung Injury
 Pneumonia Antibodies  >101 publications with Cxcl1 and Pneumonia
 Wounds and Injuries Antibodies  >87 publications with Cxcl1 and Wounds and Injuries
 Reperfusion Injury Antibodies  >84 publications with Cxcl1 and Reperfusion Injury
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >27 publications with Cxcl1 and Pancreas
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