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Kras recombinant protein :: GTPase KRas (Kras) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS953185 Kras recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $585 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $780 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $860 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $885 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $990 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,115 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,120 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,125 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,215 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,615 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,700 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,715 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,160 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GTPase KRas (Kras), Recombinant Protein

 Also Known As   

Recombinant Mouse GTPase KRas (Kras)

 Product Gene Name   

Kras recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-186aa, Full length protein
 Sequence    MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QELARSYGIP FIETSAKTRQ RVEDAFYTLV REIRQYRLKK ISKEEKTPGC VKIKKC
 3D Structure    ModBase 3D Structure for P32883
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Kras recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Kras recombinant protein

   This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
NCBI/Uniprot data below describe general gene information for Kras. It may not necessarily be applicable to this product.
 NCBI GI #    266458391
 NCBI GeneID    16653
 NCBI Accession #    NP_067259.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_021284.6 [Other Products]
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 UniProt Primary Accession #    P32883 [Other Products]
 UniProt Secondary Accession #    P04200; P08643 [Other Products]
 UniProt Related Accession #    P32883 [Other Products]
 Molecular Weight    21,483 Da
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 NCBI Official Full Name    GTPase KRas
 NCBI Official Synonym Full Names    Kirsten rat sarcoma viral oncogene homolog
 NCBI Official Symbol    Kras [Similar Products]
 NCBI Official Synonym Symbols   
ras; p21B; K-Ras; K-ras; Kras2; Ki-ras; Kras-2; K-Ras 2; c-K-ras; AI929937; c-Ki-ras
[Similar Products]
 NCBI Protein Information    GTPase KRas
 UniProt Protein Name    GTPase KRas
 UniProt Synonym Protein Names   
K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras
 Protein Family    GTPase
 UniProt Gene Name    Kras [Similar Products]
 UniProt Synonym Gene Names    Kras2 [Similar Products]
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 UniProt Comments for Kras    Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (). Plays an important role in the regulation of cell proliferation (PubMed:6474169, PubMed:1352876). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner ().
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 Research Articles on Kras    1. Given the significance of KRAS activity as a driver in tumorigenesis, identification of K147 acetylation as a novel post-translational modification directed by SIRT2 in vivo may provide a better understanding of the mechanistic link regarding the crosstalk between non-genetic and genetic factors in KRAS driven tumors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Kras recombinant proteinPathways associated with Kras recombinant protein
 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with Kras and FLNA
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Activation Of RAS In B Cells Pathway antibodies  Activation Of RAS In B Cells Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
Diseases associated with Kras recombinant proteinOrgans/Tissues associated with Kras recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5373 publications with Kras and Neoplasms
 Carcinoma Antibodies  >2363 publications with Kras and Carcinoma
 Colorectal Neoplasms Antibodies  >1704 publications with Kras and Colorectal Neoplasms
 Adenocarcinoma Antibodies  >1518 publications with Kras and Adenocarcinoma
 Lung Neoplasms Antibodies  >1081 publications with Kras and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >850 publications with Kras and Cell Transformation, Neoplastic
 Pancreatic Neoplasms Antibodies  >532 publications with Kras and Pancreatic Neoplasms
 Neoplasm Metastasis Antibodies  >529 publications with Kras and Neoplasm Metastasis
 Carcinoma, Non-Small-Cell Lung Antibodies  >522 publications with Kras and Carcinoma, Non-Small-Cell Lung
 Neoplasms, Experimental Antibodies  >443 publications with Kras and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1399 publications with Kras and Lung
 Liver Antibodies  >437 publications with Kras and Liver
 Skin Antibodies  >331 publications with Kras and Skin
 Pancreas Antibodies  >274 publications with Kras and Pancreas
 Brain Antibodies  >254 publications with Kras and Brain
 Muscle Antibodies  >197 publications with Kras and Muscle
 Lymph Node Antibodies  >180 publications with Kras and Lymph Node
 Bone Antibodies  >175 publications with Kras and Bone
 Thyroid Antibodies  >155 publications with Kras and Thyroid
 Intestine Antibodies  >154 publications with Kras and Intestine
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