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Kras recombinant protein :: GTPase KRas (Kras) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS953185 Kras recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $935 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $935 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,155 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,155 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,395 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,395 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,845 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,845 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GTPase KRas (Kras), Recombinant Protein

 Also Known As   

Recombinant Mouse GTPase KRas (Kras)

 Product Synonym Names    GTPase KRas; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-rasCleaved into the following chain:; 1. GTPase KRas, N-terminally processed
 Product Gene Name   

Kras recombinant protein

[Similar Products]
 Product Synonym Gene Name    Kras; Kras2 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-186
 Sequence    MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QELARSYGIP FIETSAKTRQ RVEDAFYTLV REIRQYRLKK ISKEEKTPGC VKIKKC
 3D Structure    ModBase 3D Structure for P32883
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Kras recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Kras. It may not necessarily be applicable to this product.
 NCBI GI #    266458391
 NCBI GeneID    16653
 NCBI Accession #    NP_067259.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_021284.6 [Other Products]
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 UniProt Primary Accession #    P32883 [Other Products]
 UniProt Secondary Accession #    P04200; P08643 [Other Products]
 UniProt Related Accession #    P32883 [Other Products]
 Molecular Weight    21,483 Da
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 NCBI Official Full Name    GTPase KRas
 NCBI Official Synonym Full Names    v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
 NCBI Official Symbol    Kras [Similar Products]
 NCBI Official Synonym Symbols   
ras; p21B; K-ras; Kras2; Ki-ras; Kras-2; AI929937
[Similar Products]
 NCBI Protein Information    GTPase KRas; K-Ras 2; c-K-ras; c-Ki-ras; p21 protein; Kirsten rat sarcoma oncogene 2, expressed
 UniProt Protein Name    GTPase KRas
 UniProt Synonym Protein Names   
K-Ras 2; Ki-Ras; c-K-ras; c-Ki-rasCleaved into the following chain:GTPase KRas, N-terminally processed
 Protein Family    GTPase
 UniProt Gene Name    Kras [Similar Products]
 UniProt Synonym Gene Names    Kras2 [Similar Products]
 UniProt Entry Name    RASK_MOUSE
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 UniProt Comments for Kras    KRas: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Interacts with PHLPP. Interacts (active GTP-bound form preferentially) with RGS14. Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase- activating protein (GAP). Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein; G protein, monomeric, Ras; Oncoprotein; G protein, monomeric; Motility/polarity/chemotaxis

Cellular Component: extrinsic to internal side of plasma membrane; focal adhesion; mitochondrion; membrane; cytoplasm; plasma membrane; intracellular; lipid raft

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; GMP binding; nucleotide binding; protein complex binding; LRR domain binding

Biological Process: regulation of long-term neuronal synaptic plasticity; positive regulation of nitric-oxide synthase activity; cytokine and chemokine mediated signaling pathway; signal transduction; regulation of synaptic transmission, GABAergic; activation of NF-kappaB transcription factor; positive regulation of MAP kinase activity; positive regulation of Rac protein signal transduction; negative regulation of cell differentiation; homeostasis of number of cells within a tissue; small GTPase mediated signal transduction; Ras protein signal transduction; positive regulation of cell proliferation; visual learning; striated muscle cell differentiation; negative regulation of neuron apoptosis; positive regulation of protein amino acid phosphorylation; actin cytoskeleton organization and biogenesis
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 Research Articles on Kras    1. These observations provide genetic evidence for an essential role of Ras proteins in the control of keratinocyte and epidermal proliferation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Kras recombinant proteinPathways associated with Kras recombinant protein
 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with Kras and FLNA
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Activation Of RAS In B Cells Pathway antibodies  Activation Of RAS In B Cells Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
Diseases associated with Kras recombinant proteinOrgans/Tissues associated with Kras recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2677 publications with Kras and Carcinoma
 Colorectal Neoplasms Antibodies  >1914 publications with Kras and Colorectal Neoplasms
 Adenocarcinoma Antibodies  >1738 publications with Kras and Adenocarcinoma
 Lung Neoplasms Antibodies  >1251 publications with Kras and Lung Neoplasms
 Pancreatic Neoplasms Antibodies  >623 publications with Kras and Pancreatic Neoplasms
 Carcinoma, Non-Small-Cell Lung Antibodies  >605 publications with Kras and Carcinoma, Non-Small-Cell Lung
 Neoplasm Metastasis Antibodies  >599 publications with Kras and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >482 publications with Kras and Neoplasms, Experimental
 Colonic Neoplasms Antibodies  >421 publications with Kras and Colonic Neoplasms
 Adenoma Antibodies  >343 publications with Kras and Adenoma
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Kras and Bone
 Connective Tissue Antibodies  >4 publications with Kras and Connective Tissue
 Heart Antibodies  >3 publications with Kras and Heart
 Muscle Antibodies  >3 publications with Kras and Muscle
 Brain Antibodies  >3 publications with Kras and Brain
 Vascular Antibodies  >2 publications with Kras and Vascular
 Embryonic Tissue Antibodies  >2 publications with Kras and Embryonic Tissue
 Ear Antibodies  >1 publications with Kras and Ear
 Kidney Antibodies  >1 publications with Kras and Kidney
 Umbilical Cord Antibodies  >1 publications with Kras and Umbilical Cord
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