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LGALS3 recombinant protein :: Galectin-3 protein (LGALS3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS969166
SDS-PAGE
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.05 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $265 +1 FREE 8GB USB
0.25 mg  /  $495 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Galectin-3 protein (LGALS3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Galectin-3 protein (LGALS3) (Active)

 Product Synonym Names    Gal-3; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein
 Product Gene Name   

LGALS3 recombinant protein

[Similar Products]
 Product Synonym Gene Name    MAC2 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-250aa, Full Length of Mature Protein
 Sequence    ADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYPGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSATGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SKLGISGDID LTSASYTMI
 OMIM    M57710 mRNA
 3D Structure    ModBase 3D Structure for P17931
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 Host    E Coli
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 Purity/Purification    >=98% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
 Biological Activity    Fully biologically active when compared to standard. The ED50 as determined by its ability to agglutinate human red blood cells is less than 10 ug/ml.
 Storage Buffer    0.2 um filtered 20 mM PB, pH 7.4, 150mM NaCl,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
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 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of LGALS3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for LGALS3 recombinant protein

   Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. {ECO:0000250, ECO:0000269|PubMed:15181153, ECO:0000269|PubMed:19594635, ECO:0000269|PubMed:19616076}.
 Product Categories/Family for LGALS3 recombinant protein    Biological Active Protein; Neuroscience 
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 SDS-PAGE of LGALS3 recombinant protein    LGALS3 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for LGALS3. It may not necessarily be applicable to this product.
 NCBI GI #    115430223
 NCBI GeneID    3958
 NCBI Accession #    NP_002297.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002306.3 [Other Products]
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 UniProt Primary Accession #    P17931 [Other Products]
 UniProt Secondary Accession #    Q16005; Q6IBA7; Q96J47; B2RC38 [Other Products]
 UniProt Related Accession #    P17931 [Other Products]
 Molecular Weight    26.0 kDa
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 NCBI Official Full Name    galectin-3 isoform 1
 NCBI Official Synonym Full Names    galectin 3
 NCBI Official Symbol    LGALS3 [Similar Products]
 NCBI Official Synonym Symbols   
L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2
[Similar Products]
 NCBI Protein Information    galectin-3
 UniProt Protein Name    Galectin-3
 UniProt Synonym Protein Names   
35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen
 UniProt Gene Name    LGALS3 [Similar Products]
 UniProt Synonym Gene Names    MAC2; Gal-3; CBP 35; GALBP [Similar Products]
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 NCBI Summary for LGALS3    This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]
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 UniProt Comments for LGALS3    Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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 Research Articles on LGALS3    1. Galectin-3 levels and cystatin-C levels are independent predictors of 26-month mortality in patients with chronic heart failure
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LGALS3 recombinant proteinPathways associated with LGALS3 recombinant protein
 Reference Product  PubMed Publications
 LGALS3BP recombinant protein  >45 publications with LGALS3 and LGALS3BP
 MMP2 recombinant protein  >7 publications with LGALS3 and MMP2
 GEMIN4 recombinant protein  >5 publications with LGALS3 and GEMIN4
 TNC recombinant protein  >4 publications with LGALS3 and TNC
 PRKCSH recombinant protein  >2 publications with LGALS3 and PRKCSH
 DDOST recombinant protein  >2 publications with LGALS3 and DDOST
 NRAS recombinant protein  >2 publications with LGALS3 and NRAS
 HRAS recombinant protein  >2 publications with LGALS3 and HRAS
 PTPRC recombinant protein  >1 publications with LGALS3 and PTPRC
 SUFU recombinant protein  >1 publications with LGALS3 and SUFU
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Advanced Glycosylation Endproduct Receptor Signaling Pathway antibodies  Advanced Glycosylation Endproduct Receptor Signaling Pathway Diagram
 Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies  Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
Diseases associated with LGALS3 recombinant proteinOrgans/Tissues associated with LGALS3 recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >580 publications with LGALS3 and Carcinoma
 Inflammation Antibodies  >333 publications with LGALS3 and Inflammation
 Adenocarcinoma Antibodies  >246 publications with LGALS3 and Adenocarcinoma
 Fibrosis Antibodies  >216 publications with LGALS3 and Fibrosis
 Disease Models, Animal Antibodies  >181 publications with LGALS3 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >166 publications with LGALS3 and Neoplasm Metastasis
 Adenoma Antibodies  >145 publications with LGALS3 and Adenoma
 Breast Neoplasms Antibodies  >122 publications with LGALS3 and Breast Neoplasms
 Lung Diseases Antibodies  >107 publications with LGALS3 and Lung Diseases
 Necrosis Antibodies  >95 publications with LGALS3 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >711 publications with LGALS3 and Blood
 Thyroid Antibodies  >319 publications with LGALS3 and Thyroid
 Heart Antibodies  >295 publications with LGALS3 and Heart
 Vascular Antibodies  >211 publications with LGALS3 and Vascular
 Brain Antibodies  >185 publications with LGALS3 and Brain
 Lung Antibodies  >143 publications with LGALS3 and Lung
 Kidney Antibodies  >141 publications with LGALS3 and Kidney
 Liver Antibodies  >141 publications with LGALS3 and Liver
 Bone Antibodies  >123 publications with LGALS3 and Bone
 Muscle Antibodies  >119 publications with LGALS3 and Muscle
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