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LGALS4 recombinant protein :: Galectin-4 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS203426
SDS-Page
Unit / Price
0.1 mg  /  $285 +1 FREE 8GB USB
0.5 mg  /  $640 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Galectin-4 (LGALS4), Recombinant Protein

 Also Known As   

Galectin-4, 1-323aa, Human, His tag, E Coli (Bioactivity Validated)

 Product Synonym Names    LGALS4; GAL4; L36LBP; Lactose-binding lectin 4; Antigen NY CO 27; Antigen NYCO27; GAL 4; Galectin 4; Galectin4; Lectin galactoside binding soluble 4; Homo sapiens galectin4 mRNA complete cds; L 36 lactose binding protein; L36 lactose binding protein; Lactose binding lectin 4
 Product Gene Name   

LGALS4 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI
 OMIM    AB006781 mRNA
 3D Structure    ModBase 3D Structure for P56470
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 Host    E Coli
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 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 1mM DTT.
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
 Endotoxin Level    < 1.0 EU per 1 microgram of protein (determined by LAL method)
 Biological Activity    The ED50 for this effect is is equal or less than 2 ug/ml. Measured by its ability to ability to agglutinate human red blood cells.
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of LGALS4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for LGALS4 recombinant protein

   Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic reactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. Recombinant Galectin-4 protein was expressed in E Coli and purified by using conventional chromatography techniques.
 Product Categories/Family for LGALS4 recombinant protein    Adhesion & Movement
 Applications Tested/Suitable for LGALS4 recombinant protein   

SDS-PAGE

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 SDS-Page of LGALS4 recombinant protein    LGALS4 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for LGALS4. It may not necessarily be applicable to this product.
 NCBI GI #    5453712
 NCBI GeneID    3960
 NCBI Accession #    NP_006140 [Other Products]
 NCBI GenBank Nucleotide #    NM_006149.3 [Other Products]
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 UniProt Primary Accession #    P56470 [Other Products]
 UniProt Related Accession #    P56470 [Other Products]
 Molecular Weight    38.1 kDa (343aa), confirmed by MALDI-TOF. [Similar Products]
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 NCBI Official Full Name    galectin-4
 NCBI Official Synonym Full Names    galectin 4
 NCBI Official Symbol    LGALS4 [Similar Products]
 NCBI Official Synonym Symbols   
GAL4; L36LBP
[Similar Products]
 NCBI Protein Information    galectin-4
 UniProt Protein Name    Galectin-4
 UniProt Synonym Protein Names   
Antigen NY-CO-27; L-36 lactose-binding protein; L36LBP; Lactose-binding lectin 4
 Protein Family    Galectin
 UniProt Gene Name    LGALS4 [Similar Products]
 UniProt Synonym Gene Names    Gal-4; L36LBP [Similar Products]
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 NCBI Summary for LGALS4    The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LGALS4    Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.
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Product References and Citations for LGALS4 recombinant protein

   Huflejt ME., et al. (1997) J Biol Chem. 272 (22):14294-303. ; Huflejt ME., et al. (2004) Glycoconj J. 20 (4):247-55.;
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 Research Articles on LGALS4    1. Haplotype formed from two promoter SNPs rs116896264 and rs73933062 is associated with galectin-4 overexpression in colorectal cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with LGALS4 recombinant proteinOrgans/Tissues associated with LGALS4 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >16 publications with LGALS4 and Inflammation
 Neoplasm Metastasis Antibodies  >15 publications with LGALS4 and Neoplasm Metastasis
 Liver Diseases Antibodies  >9 publications with LGALS4 and Liver Diseases
 Liver Neoplasms Antibodies  >8 publications with LGALS4 and Liver Neoplasms
 Lung Neoplasms Antibodies  >8 publications with LGALS4 and Lung Neoplasms
 Breast Neoplasms Antibodies  >7 publications with LGALS4 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >6 publications with LGALS4 and Neoplasms, Experimental
 Cell Transformation, Neoplastic Antibodies  >5 publications with LGALS4 and Cell Transformation, Neoplastic
 Brain Diseases Antibodies  >5 publications with LGALS4 and Brain Diseases
 Adenoma Antibodies  >4 publications with LGALS4 and Adenoma
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >47 publications with LGALS4 and Intestine
 Blood Antibodies  >41 publications with LGALS4 and Blood
 Liver Antibodies  >24 publications with LGALS4 and Liver
 Stomach Antibodies  >17 publications with LGALS4 and Stomach
 Brain Antibodies  >12 publications with LGALS4 and Brain
 Lung Antibodies  >12 publications with LGALS4 and Lung
 Kidney Antibodies  >11 publications with LGALS4 and Kidney
 Embryonic Tissue Antibodies  >6 publications with LGALS4 and Embryonic Tissue
 Bladder Antibodies  >5 publications with LGALS4 and Bladder
 Pancreas Antibodies  >4 publications with LGALS4 and Pancreas
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