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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

GRP recombinant protein :: Gastrin-releasing peptide Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS950021
SDS-Page
Unit / Price
0.2 mg  /  $460 +1 FREE 8GB USB
0.5 mg  /  $750 +1 FREE 8GB USB
1 mg  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Gastrin-releasing peptide (GRP), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Gastrin-releasing peptide

 Product Synonym Names    GRP-10
 Product Gene Name   

GRP recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS950021 Technical Datasheet    Technical Datasheet PDF
 Sequence Positions    54-121
 Sequence    STGESSSVSE RGSLKQQLRE YIRWEEAARN LLGLIEAKEN RNHQPPQPKA LGNQQPSWDS EDSSNFKD
 OMIM    137260
 3D Structure    ModBase 3D Structure for P07492
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GRP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for GRP recombinant protein

   GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent mory for fear.
 Product Categories/Family for GRP recombinant protein    Signal Transduction
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 SDS-Page of GRP recombinant protein    GRP recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for GRP. It may not necessarily be applicable to this product.
 NCBI GI #    60498997
 NCBI GeneID    2922
 NCBI Accession #    NP_001012530.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001012512.2 [Other Products]
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 UniProt Primary Accession #    P07492 [Other Products]
 UniProt Secondary Accession #    P07491; P81553; Q14454; Q53YA0; Q9BSY7 [Other Products]
 UniProt Related Accession #    P07492 [Other Products]
 Molecular Weight    35.1kD
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 NCBI Official Full Name    gastrin-releasing peptide isoform 2
 NCBI Official Synonym Full Names    gastrin releasing peptide
 NCBI Official Symbol    GRP [Similar Products]
 NCBI Official Synonym Symbols   
BN; GRP-10; proGRP; preproGRP
[Similar Products]
 NCBI Protein Information    gastrin-releasing peptide
 UniProt Protein Name    Gastrin-releasing peptide
 UniProt Synonym Protein Names   
Neuromedin-CAlternative name(s):GRP-10
 Protein Family    Gastrin-releasing peptide
 UniProt Gene Name    GRP [Similar Products]
 UniProt Synonym Gene Names    GRP [Similar Products]
 UniProt Entry Name    GRP_HUMAN
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 NCBI Summary for GRP    This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
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 UniProt Comments for GRP    GRP: GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP- receptor gene expression, long-term potentiation, and amygdala- dependent memory for fear. Belongs to the bombesin/neuromedin-B/ranatensin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 18q21.1-q21.32

Cellular Component: extracellular region; extracellular space

Molecular Function: neuropeptide hormone activity; receptor binding

Biological Process: neuropeptide signaling pathway; signal transduction
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Product References and Citations for GRP recombinant protein

   Two prohormones for gastrin-releasing peptide are encoded by two mRNAs differing by 19 nucleotides.Spindel E.R., Zilberberg M.D., Habener J.F., Chin W.W.Proc. Natl. Acad. Sci. U.S.A. 83:19-23(1986)
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 Research Articles on GRP    1. Our results suggest that progastrin inhibits the acquisition of a M2-phenotype in human macrophages.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GRP recombinant proteinPathways associated with GRP recombinant protein
 Reference Product  PubMed Publications
 CCK recombinant protein  >111 publications with GRP and CCK
 NMBR recombinant protein  >24 publications with GRP and NMBR
 NTS recombinant protein  >4 publications with GRP and NTS
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Incretin Synthesis, Secretion, And Inactivation Pathway antibodies  Incretin Synthesis, Secretion, And Inactivation Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with GRP recombinant proteinOrgans/Tissues associated with GRP recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >454 publications with GRP and Carcinoma
 Lung Neoplasms Antibodies  >229 publications with GRP and Lung Neoplasms
 Lung Diseases Antibodies  >220 publications with GRP and Lung Diseases
 Adenocarcinoma Antibodies  >167 publications with GRP and Adenocarcinoma
 Inflammation Antibodies  >137 publications with GRP and Inflammation
 Prostatic Neoplasms Antibodies  >111 publications with GRP and Prostatic Neoplasms
 Breast Neoplasms Antibodies  >90 publications with GRP and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >69 publications with GRP and Neoplasms, Experimental
 Necrosis Antibodies  >62 publications with GRP and Necrosis
 Fibrosis Antibodies  >62 publications with GRP and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >431 publications with GRP and Brain
 Pancreas Antibodies  >239 publications with GRP and Pancreas
 Prostate Antibodies  >192 publications with GRP and Prostate
 Uterus Antibodies  >39 publications with GRP and Uterus
 Eye Antibodies  >38 publications with GRP and Eye
 Testis Antibodies  >11 publications with GRP and Testis
 Parathyroid Antibodies  >5 publications with GRP and Parathyroid
 Pineal Gland Antibodies  >1 publications with GRP and Pineal Gland
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