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GTF2F1 recombinant protein :: General transcription factor IIF subunit 1 (GTF2F1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS964826 GTF2F1 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,305 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,305 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,525 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,525 +1 FREE 8GB USB
1 mg (E-Coli)  /  $2,150 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,150 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,615 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,615 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

General transcription factor IIF subunit 1 (GTF2F1), Recombinant Protein

 Also Known As   

Recombinant Human General transcription factor IIF subunit 1 (GTF2F1)

 Product Synonym Names    General transcription factor IIF subunit 1; General transcription factor IIF 74 kDa subunit; Transcription initiation factor IIF subunit alpha; TFIIF-alpha; Transcription initiation factor RAP74
 Product Gene Name   

GTF2F1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    GTF2F1; RAP74 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-517
 Sequence    AALGPSSQN VTEYVVRVPK NTTKKYNIMA FNAADKVNFA TWNQARLERD LSNKKIYQEE EMPESGAGSE FNRKLREEAR RKKYGIVLKE FRPEDQPWLL RVNGKSGRKF KGIKKGGVTE NTSYYIFTQC PDGAFEAFPV HNWYNFTPLA RHRTLTAEEA EEEWERRNKV LNHFSIMQQR RLKDQDQDED EEEKEKRGRR KASELRIHDL EDDLEMSSDA SDASGEEGGR VPKAKKKAPL AKGGRKKKKK KGSDDEAFED SDDGDFEGQE VDYMSDGSSS SQEEPESKAK APQQEEGPKG VDEQSDSSEE SEEEKPPEED KEEEEEKKAP TPQEKKRRKD SSEESDSSEE SDIDSEASSA LFMAKKKTPP KRERKPSGGS SRGNSRPGTP SAEGGSTSST LRAAASKLEQ GKRVSEMPAA KRLRLDTGPQ SLSGKSTPQP PSGKTTPNSG DVQVTEDAVR RYLTRKPMTT KDLLKKFQTK KTGLSSEQTV NVLAQILKRL NPERKMINDK MHFSLKE
 OMIM    189968
 3D Structure    ModBase 3D Structure for P35269
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GTF2F1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for GTF2F1. It may not necessarily be applicable to this product.
 NCBI GI #    156104891
 NCBI GeneID    2962
 NCBI Accession #    NP_002087.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002096.2 [Other Products]
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 UniProt Primary Accession #    P35269 [Other Products]
 UniProt Secondary Accession #    Q9BWN0; B2RCS0 [Other Products]
 UniProt Related Accession #    P35269 [Other Products]
 Molecular Weight    58,240 Da
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 NCBI Official Full Name    general transcription factor IIF subunit 1
 NCBI Official Synonym Full Names    general transcription factor IIF, polypeptide 1, 74kDa
 NCBI Official Symbol    GTF2F1 [Similar Products]
 NCBI Official Synonym Symbols   
BTF4; RAP74; TF2F1; TFIIF
[Similar Products]
 NCBI Protein Information    general transcription factor IIF subunit 1; TFIIF-alpha; transcription initiation factor RAP74; general transcription factor IIF 74 kDa subunit; transcription initiation factor IIF subunit alpha
 UniProt Protein Name    General transcription factor IIF subunit 1
 UniProt Synonym Protein Names   
General transcription factor IIF 74 kDa subunit; Transcription initiation factor IIF subunit alpha; TFIIF-alpha; Transcription initiation factor RAP74
 Protein Family    General transcription factor
 UniProt Gene Name    GTF2F1 [Similar Products]
 UniProt Synonym Gene Names    RAP74; TFIIF-alpha [Similar Products]
 UniProt Entry Name    T2FA_HUMAN
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 UniProt Comments for GTF2F1    GTF2F1: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Heterodimer of an alpha and a beta subunit. Interacts with GTF2F2, CTDP1, TAF6/TAFII80 and URI1. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the TFIIF alpha subunit family.

Protein type: Kinase, protein; EC 2.7.11.1; Transcription initiation complex; ATYPICAL group; GTF2F1 family

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; transcription factor TFIIF complex; cell junction; nucleus

Molecular Function: protein binding; DNA binding; phosphatase activator activity; transcription coactivator activity; catalytic activity; transcription factor binding

Biological Process: positive regulation of catalytic activity; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; mRNA capping; viral reproduction; positive regulation of RNA elongation from RNA polymerase II promoter; positive regulation of viral transcription; response to virus; RNA splicing; RNA elongation from RNA polymerase II promoter; gene expression
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 Research Articles on GTF2F1    1. These results suggest that Mediator structural shifts induced by activator binding help stably orient pol II prior to transcription initiation within the human mediator-RNA polymerase II-TFIIF assembly.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GTF2F1 recombinant proteinPathways associated with GTF2F1 recombinant protein
 Reference Product  PubMed Publications
 GTF2F2 recombinant protein  >2 publications with GTF2F1 and GTF2F2
 TBP recombinant protein  >1 publications with GTF2F1 and TBP
 GTF2B recombinant protein  >1 publications with GTF2F1 and GTF2B
 Products by Pathway  Pathway Diagram
 Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway antibodies  Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway antibodies  Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway Diagram
 Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies  Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
 Formation Of RNA Pol II Elongation Complex Pathway antibodies  Formation Of RNA Pol II Elongation Complex Pathway Diagram
 Formation Of The Early Elongation Complex Pathway antibodies  Formation Of The Early Elongation Complex Pathway Diagram
 Formation Of The HIV-1 Early Elongation Complex Pathway antibodies  Formation Of The HIV-1 Early Elongation Complex Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
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