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Klk7 recombinant protein :: Glandular kallikrein-7 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS949033
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $780 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $925 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,050 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,165 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,170 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,185 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,685 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,775 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,800 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,250 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glandular kallikrein-7 (Klk7), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Glandular kallikrein-7, submandibular/renal

 Product Synonym Names    Esterase B; Kallikrein-related protein K1; Proteinase ARSKG-7; Tissue kallikrein
 Product Gene Name   

Klk7 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    25-261aa; Full Length
 Sequence    VIGGYKCEKN SQPWQVALYS FTKYLCGGVL IDPSWVITAA HCSSNNYQVW LGRNNLLEDE PFAQHRLVSQ SFPHPDYKPF LMRNHTRKPG DDHSNDLMLL HLSQPADITD GVKVIDLPTE EPKVGSTCLA SGWGSTKPLI WEFPDDLQCV NIHLLSNEKC IKAYKEKVTD LMLCAGELEG GKDTCTGDSG GPLLCDGVLQ GITSWGSVPC AKTNMPAIYT KLIKFTSWIK EVMKENP
 3D Structure    ModBase 3D Structure for P36373
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Klk7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Klk7 recombinant protein

   Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Predominant kallikrein protein in the kidney.
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 SDS-PAGE of Klk7 recombinant protein    Klk7 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Klk7. It may not necessarily be applicable to this product.
 NCBI GI #    6981132
 NCBI GeneID    24523
 NCBI Accession #    NP_036725.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012593.1 [Other Products]
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 UniProt Primary Accession #    P36373 [Other Products]
 Molecular Weight    30.38kD
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 NCBI Official Full Name    kallikrein 1
 UniProt Protein Name    Glandular kallikrein-7, submandibular/renal
 UniProt Synonym Protein Names   
Esterase B; Kallikrein-related protein K1; Proteinase A; RSKG-7; Tissue kallikrein
 Protein Family    Glandular kallikrein
 UniProt Gene Name    Klk7 [Similar Products]
 UniProt Synonym Gene Names    Klk-7; rGK-7 [Similar Products]
 UniProt Entry Name    KLK7_RAT
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 NCBI Summary for Klk7    serine protease; involved in processing of bioactive peptides [RGD, Feb 2006]
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 UniProt Comments for Klk7    KLK7: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; EC 3.4.21.35; Secreted, signal peptide; Protease

Cellular Component: acrosome; apical part of cell; nucleus

Molecular Function: endopeptidase activity; serine-type endopeptidase activity

Biological Process: positive regulation of acute inflammatory response; positive regulation of apoptosis; positive regulation of cell proliferation; proteolysis; response to nutrient
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Product References and Citations for Klk7 recombinant protein

   Molecular cloning and characterization of two rat renal kallikrein genes.Chen Y.-P., Chao J., Chao L.Biochemistry 27:7189-7196(1988) Characterization of serine proteinases isolated from rat submaxillary gland with special reference to the degradation of rat kininogens by these enzymes.Kato H., Nakanishi E., Enjyoji K., Hayashi I., Oh-Ishi S., Iwanaga S.J. Biochem. 102:1389-1404(1987) Substrate specificity of two kallikrein family gene products isolated from the rat submaxillary gland.Elmoujahed A., Gutman N., Brillard M., Gauthier F.FEBS Lett. 265:137-140(1990) The expression of two kallikrein gene family members in the rat kidney.Brady J.M., MacDonald R.J.Arch. Biochem. Biophys. 278:342-349(1990)
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 Research Articles on Klk7    1. Tissue kallikrein 1 and TIMP1 expressed in a coexpression vector synergistically inhibited the proliferation of rat vascular smooth muscle cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Klk7 recombinant proteinPathways associated with Klk7 recombinant protein
 Reference Product  PubMed Publications
 Set recombinant protein  >4 publications with Klk7 and Set
 Products by Pathway  Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
Diseases associated with Klk7 recombinant proteinOrgans/Tissues associated with Klk7 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >21 publications with Klk7 and Inflammation
 Disease Models, Animal Antibodies  >5 publications with Klk7 and Disease Models, Animal
 Hyperplasia Antibodies  >5 publications with Klk7 and Hyperplasia
 Neoplasms, Experimental Antibodies  >4 publications with Klk7 and Neoplasms, Experimental
 Lung Diseases Antibodies  >4 publications with Klk7 and Lung Diseases
 Necrosis Antibodies  >3 publications with Klk7 and Necrosis
 Abnormalities, Drug-Induced Antibodies  >1 publications with Klk7 and Abnormalities, Drug-Induced
 Insulin Resistance Antibodies  >1 publications with Klk7 and Insulin Resistance
 Liver Neoplasms Antibodies  >1 publications with Klk7 and Liver Neoplasms
 Kidney Diseases Antibodies  >1 publications with Klk7 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Salivary Gland Antibodies  >5 publications with Klk7 and Salivary Gland
 Kidney Antibodies  >3 publications with Klk7 and Kidney
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