NP_058703.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Related Accession #
NCBI Official Full Name
glutamate decarboxylase 1
NCBI Official Synonym Full Names
glutamate decarboxylase 1
NCBI Official Synonym Symbols
NCBI Protein Information
glutamate decarboxylase 1; GAD-67; glutamic acid decarboxylase 1; Glutamate decarboxylase 1 (brain); 67 kDa glutamic acid decarboxylase; glutamate decarboxylase 67 kDa isoform; glutamate decarboxylase 1 variant GAD67NT
UniProt Protein Name
Glutamate decarboxylase 1
UniProt Synonym Protein Names
67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform
UniProt Synonym Gene Names
UniProt Entry Name
DCE1_RAT
NCBI Summary for GAD1
plays a role in the biosynthesis of gamma-aminobutyric acid [RGD, Feb 2006]
UniProt Comments for GAD1
GAD67: Catalyzes the production of GABA. Homodimer. Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. Belongs to the group II decarboxylase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Other Amino Acids Metabolism - beta-alanine; Mitochondrial; Lyase; Amino Acid Metabolism - alanine, aspartate and glutamate; Carbohydrate Metabolism - butanoate; Other Amino Acids Metabolism - taurine and hypotaurine; EC 4.1.1.15
Cellular Component: mitochondrion; axon; cytoplasm; presynaptic active zone; synapse; nerve terminal; intracellular; cell cortex
Molecular Function: glutamate binding; glutamate decarboxylase activity; protein heterodimerization activity; protein N-terminus binding; pyridoxal phosphate binding
Biological Process: response to drug; gamma-aminobutyric acid biosynthetic process; neurotransmitter biosynthetic process
Research Articles on GAD1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with GAD1 recombinant protein
Diseases associated with GAD1 recombinant protein
Organs/Tissues associated with GAD1 recombinant protein
|